Dispensing and Adverse Drug Reactions
Aspirin with antacids will cause: A. Alteration of pH B. Complexation and adsorption C. Alteration of GIT flora D. Alteration of motility
A. Alteration of pH
The reaction is classified under Bizarre reactions (typeB): A. Anaphylactic shock B. Teratogenesis C. Adverse effect D. Drug dependence
A. Anaphylactic shock
The most serious drug-induced blood disorder: A. Aplastic anemia B. Leukemia C. Agranulocuytosis D. Thrombocytopenia
A. Aplastic anemia
Drug that should not be given to patients who have undergone surgery including dental surgery: A. Aspirin B. Acetaminophen C. Ibuprofen D. All of these answers
A. Aspirin
Theophylline is used for: A. Asthmatic B. Diabetic C. Hypertensive patients D. All of these answers
A. Asthmatic
The chemical substance used commonly in running a GI series is: A. Barium sulfate B. Fluorescein dye C. Radioactive iodine C. Sodium bicarbonate D. Sodium carbonate
A. Barium sulfate
A metal catalyzed oxidation reaction pathway can be prevented by: A. Chelating agents B. Antioxidant C. Surface active agents D. None of these answers
A. Chelating agents
Patron saints of medicine and pharmacy: A. Cosmas and Damian B. St. Peter C. George Ebers D. Don Leon Maria Guerrero
A. Cosmas and Damian
A formulation of FeSO4 suspension cannot use acacia as a suspending agent, because the final product may exhibit: A. Gelatinization B. precipitation C. cementation D. oxidation
A. Gelatinization
Which of the following factors influence drug metabolism and metabolic pathway? A. Genetic variation B. Drug dosage C. Physiologic or disease state D. All of these answers
A. Genetic variation
A fever response to antibiotic therapy caused by the sudden release of endotoxins from various killed microorganism is called: A. Herxheimer reaction B. Lyell's syndrome C. skin reactions D. anaphylactic reaction
A. Herxheimer reaction
What will result if the distribution of drugs is slower than the processes of biotransformation and elimination? A. High blood levels of drugs B. Low blood levels of drugs C. synergism e. failure to attain diffusion equilibrium D. potentiation
A. High blood levels of drugs
The degradation reaction for aspirin involves: A. Hydrolysis B. Racemization C. Oxidation D. Photolysis
A. Hydrolysis
Allergic reactions that are due to a persons's immune response: A. Hypersensitivity B. Idiosyncracy C. Synergy D. Potentiation
A. Hypersensitivity
Official name of drug products containing 2 or more active ingredients with single INN: A. INN of the combination products B. Generic names of 2 or more active ingredients C. Based on the nomenclature used by the PNDF D. Products with standards formulation included in the current PNDF
A. INN of the combination products
Adverse drug reaction characterize by exaggerated or inordinate response to normal doses of a drug: A. Idiosyncrasy B. Allergy C. Hypersensitivity D. Potentiation
A. Idiosyncrasy
Biological half-life of many drugs is often prolonged in new born infants because of: A. Incompletely developed enzyme system B. Microsomal enzyme inhibition C. Higher protein binding D. Well-developed renal function
A. Incompletely developed enzyme system
Denaturations of emulsions is characterized by: A. Irreversible precipitation B. Reversible precipitation C. Creaming D. Changing of external phase E. C and D
A. Irreversible precipitation
Which of the following properties would characterize a drug when it is bound to plasma albumin? A. It is biologically inactive B. it is promptly metabolized C. It can pass through the glomerulus D. a and b
A. It is biologically inactive
Regulated drugs, except: A. LSD B. amphetamine C. methaqualone D. Phenobarbital
A. LSD
The principal use of magnesium stearate in pharmaceutics is as/an: A. Lubricant B. antacid C. source of magnesium ion D. disintegrant E. binder
A. Lubricant
An example of subscription: A. M.ft.sol B. 1 tab q 6 hrs C. shake well before using D. 250 mg capsule
A. M.ft.sol
Allopurinol inhibits xanthine oxidase and thus increases the plasma levels of: A. Mercaptopurine B. chloral hydrate C. disulfiram D. aspirin
A. Mercaptopurine
Transdermal scopolomine is a drug used to prevent: A. Motion sickness B. Hypertension C. Diabetes D. Coronary insufficiency E. Rabies
A. Motion sickness
Which statement is not true regarding Lithium-NSAID combinations? A. NSAID impairs renal synthesis of broncho-dilator prostaglandin B. NSAID antagonize the renal excretion of lithium C. NSAID may cause sodium and water retention D. NSAID inhibit prostaglandin dependent renal excretion of lithium
A. NSAID impairs renal synthesis of broncho-dilator prostaglandin
The most clinically significant adverse drug reaction affecting the upper gastrointestinal tract results from the use of: A. NSAIDs B. Corticosteroids C. Enteric coated KCl tablets D. All of these answers
A. NSAIDs
This parchment scroll found in Egypt mentioned 700 drugs with formulas for more than 800 remedies: A. Papyrus Ebers B. De Materia Medica C. Remington D. USP NF
A. Papyrus Ebers
Which of the following is not used as a vehicle for injection? A. Peanut oil B. cottonseed oil C. theobroma oil D. sesame oil
A. Peanut oil
The purpose of sorbitol in formulations of soft gelatin capsules: A. Plasticizer B. Disintegrating agent C. Lubricant D. Thickener E. Emulsifier
A. Plasticizer
A primary disadvantage of ethylene glycol as a solvent in oral preparation is its: A. Potential toxicity B. Lack of solvent action C. Very limited miscibility D. High cost E. High viscosity
A. Potential toxicity
Occurs when one drug increases the action of another drug: A. Potentiation B. Antagonism C. Summation D. Summation/Potentiation
A. Potentiation
Petition for favor of healing and warning from great care and precaution: A. Rx B. Signa C. Magistral Pharmacy D. Mark thou
A. Rx
Syrup NF is: A. Self-preserving B. A supersaturated solution C. A dilute solution D. Highly unstable E. Flavored and preserved
A. Self-preserving
Benzalkonium chloride is incompatible with: A. Soap B. Cationic agent C. a&b D. NOTA
A. Soap
The use of titanium dioxide in pharmacy is in: A. Sunscreens B. antacid capsules C. capsules as diluent D. effervescent E. emulsions
A. Sunscreens
Certified dyes may not be used in the area of: A. The eye B. the scalp C. the lips D. the nose E. all of the above
A. The eye
Term for migration of the drug into the container: A. absorption B. leaching C. permeation D. vaporization
A. absorption
Violation on the part of the pharmacist in generic dispensing, except: A. adequately inform the buyer about available products that meet the prescription B. failure to record and file the prescription filed C. imposing a particular branded or product to the buyer D. failure to report to the nearest DOH office cases of incorrect prescriptions within 3 months after receipt of such prescriptions
A. adequately inform the buyer about available products that meet the prescription
Complimentary list is a list of _____ drugs when there is no response to the core essential list: A. alternative B. substitute C. Additional D. supplementary
A. alternative
UV light-sensitive substances are best protected using: A. amber bottle B. plastic container C. flint glass D. carbon box
A. amber bottle
Group of drugs commonly abused by athletes: A. anabolic steroids B. dexamethasone C. antibiotics D. vitamins
A. anabolic steroids
Simethicone is most likely to be included in what type of OTC product? A. antacids B. cough product C. decongestant D. laxative
A. antacids
The chief active constituent: A. base B. vehicle C. corrective D. adjuvant
A. base
Glass is a traditional packaging material which has been widely used for both liquid and solid dose forms. All of the following are types of glass containers, except: A. closures B. bottles C. ear and nasal dropper bottles D. containers for semi-solid preparation
A. closures
Identify the odd-man-out: A. complex formation B. insolubility C. liquefaction of solid ingredients D. polymorphism
A. complex formation
an auxillary label except: A. do not repeat B. for external use C. shake well before using D. optalmic use
A. do not repeat
A physiological or a psychological state resulting from drug administration: A. drug dependence B. drug habituation C. drug addiction D. drug tolerance
A. drug dependence
The following are guidelines for reducing drug interactions except: A. employ combination therapy B. identify patient risk factors C. educate the patient D. know properties of drugs
A. employ combination therapy
Phenobarbital and griseofulvine are ___________ of coumarin: A. enzyme inducers B. enzyme inhibitor C. antagonists D. agonists
A. enzyme inducers
Immediate remedy for anaphylaxis: A. epinephrine injection B. aspirin C. antihistamine D. antibiotic
A. epinephrine injection
When the generic name is preceded by the brand name, the prescription is: A. erroneous prescription B. violative prescription C. impossible prescription D. none
A. erroneous prescription
Which of the following does not cause a therapeutic incompatibility? A. errors in pricing B. dosage forms C. prescription writing errors D. errors of storage supply
A. errors in pricing
Camphor , menthol, acetophenetidine, phenol will form: A. eutectic combination B. liquefaction C. explosive combination D. both a&b
A. eutectic combination
All of the following untoward effects are commonly associated with cancer chemotherapy except: A. exfoliative dermatitis B. teratogenesis C. nausea D. alopecia and leukemia
A. exfoliative dermatitis
In metabolizing a standard dose of INH, Filipinos are considered: A. fast acetylators B. slow acetylators C. neither slow or fast D. same as the Caucasians
A. fast acetylators
Characterized the first exposure of the fraction of the drug metabolized in the liver: A. first pass effect B. drug-receptor interaction C. biotransformation D. pharmacokinetics
A. first pass effect
Combination of a salt substitute and potassium sparing drugs will result to: A. hyperkalemia B. tacycardia C. alkalosis D. calcemia
A. hyperkalemia
Low potassium level in blood produced by diuretics: A. hypokalemia B. hyponatria C. hypocalcemia D. hyperuricemia
A. hypokalemia
The following are manifestations of chemical incompatibilities, except: A. immiscibility B. photolysis C. gel formation D. evolution of gas
A. immiscibility
The unusual result of triturating camphor and menthol is: A. liquefaction B. synergistic effect C. solidification D. lowering of melting point
A. liquefaction
Principal site of drug metabolism: A. liver B. kidney C. stomach D. small intestine
A. liver
In acidic urine, basic drugs are: A. more ionized, hence not reabsorbed, decrease in half-life B. un-ionized, hence not reabsorbed, decrease in half-life C. more ionized hence not reabsorbed, increase in half-life D. more ionized, reabsorbed, increase half-life
A. more ionized, hence not reabsorbed, decrease in half-life
The following is/are true regarding absorption of salicylic acid: A. non-ionized form is more lipid-soluble and absorbable B. ionized form is more lipid-soluble and absorbable C. polar form is more readily absorbed D. absorption is increased when taken with an antacid
A. non-ionized form is more lipid-soluble and absorbable
Drug-drug interactions that occur when one drug alters the absorption, distribution, metabolism and excretion of the other drug: A. pharmacokinetic interactions B. pharmacologic interactions C. pharmacodynamic interactions D. all of the above
A. pharmacokinetic interactions
Many diuretics tend to cause depletion of: A. potassium B. sodium C. carbonate ion D. urea
A. potassium
The functions of suspending agents include the following, except: A. prevent oxidation-reduction reaction B. increase the viscosity of the vehicle C. slow down the rate of settling down D. cause the preparation to remain in suspension
A. prevent oxidation-reduction reaction
The objective of the Generic Law is to: A. provide the patient the choice of drugs at the lowest cost B. provide regulated drugs C. provide prohibited drugs D. use habit forming drugs
A. provide the patient the choice of drugs at the lowest cost
The following are aminoglycosides, except: A. quinidine B. Kanamycin C. Streptomycin D. Neomycin
A. quinidine
In acidic urine, acidic drugs are more un-ionized, hence: A. reabsorbed, increase in half-life B. not reabsorbed, increase ion half-life C. reabsorbed, decrease ion half-life D. not reabsorbed, decrease in half-life
A. reabsorbed, increase in half-life
The following are importance of recognizing potential incompatibilities except: A. rewarding for the pharmacist B. saving in time, money, effort C. safety for the patient D. quality medicines dispensed
A. rewarding for the pharmacist
Aspirin hydrolyzes in water giving acetic acid and: A. salicylic acid B. oxalic acid C. formic acid D. ticarboxylic acid
A. salicylic acid
For the guidance of the patient, the prescription needs: A. signa B. subscription C. superscription D. inscription
A. signa
The part of the prescription which directs the patient on what to do is: A. signa B. inscription C. subscription D. superscription
A. signa
Involves the degradation of the drug or excipients through reaction with the solvents present in the formulations: A. solvolysis B. oxidation C. photolysis D. polymerization
A. solvolysis
HLB is a system used to distinguished between: A. surfactants B. glidants C. suspending agents D. excipients E. disintegrators
A. surfactants
Well known side effects of salicylate therapy? A. tinnitus B. vomiting C. headache D. nausea
A. tinnitus
The purpose of the prescription # is: A. to identify the prescription for future reference B. as a substitute for the name of the drug C. to guide the pharmacist in costing D. to provide professional fee to medicine
A. to identify the prescription for future reference
Instruction for patient in taking the medication: A. transcription B. inscription C. superscription D. subscription
A. transcription
Route of administration where drugs are applied to the skin surface to be absorbed slowly into the systemic circulation: A. transdermal route B. inhalation route C. buccal route D. rectal route
A. transdermal route
True types of incompatibilities: A. unintentional or unexpected incompatibilities B. intentional or expected incompatibilities C. immediate incompatibilities D. delayed incompatibilities
A. unintentional or unexpected incompatibilities
A prescription where the generic name is not written: A. violative Rx B. erroneous Rx C. impossible Rx D. yellow DDB Rx
A. violative Rx
Salt of zinc that is valuable as an eyewash for the treatment of conjunctivitis: A. zinc sulfate B. zinc chloride C. zinc oxide D. all of these answers
A. zinc sulfate
A solution contains 3 gr of a drug per fluid ounce. What is the percentage w/v of the solution? A. 0.66% B. 0.59% C. 10.0% D. 1.0% E. 6.5%
B. 0.59%
A mathematical model for synergism: A. 1+1=2 B. 1+1=3 C. 0+1=2 D. 1+1=0
B. 1+1=3
How many mL will you dispense for a prescription calling for a 100g of a liquid substance with a sp.Gr. of 1.25? A. 75mL B. 80mL C. 85mL D. 90mL
B. 80mL
An ointment is prepared by incorporating 10g of a drug into 100g of white petrolatum. What is the percent w/w of active ingredient? A. 10.0% B. 9.1% C. 0.91% D. 0.95% E. none of the above
B. 9.1%
How many grains of a drug is needed to make 4 fluid ounces of a 5% (w/v) solution? A. 91 grains B. 96 grains C. 48 grains D. 100 grains E. 24 grains
B. 96 grains
Glucose is not subject to hydrolysis because it is: A. a disaccharide B. A monosaccharide C. A polysaccharide D. Insoluble E. Both b and c
B. A monosaccharide
A reaction that is noxious and unintended, which occurs in doses used in man for prophylaxis, diagnosis and therapy? A. Drug interaction B. Adverse drug reaction C. Adverse drug effects D. Pharmacodynamic effects
B. Adverse drug reaction
Reactions which are noxious, unintended and which occur at doses normally use in man for prophylaxis, diagnosis or therapy: A. Drug interactions B. Adverse drug reaction C. Pharmacodynamic interactions D. Therapeutic incompatibilities
B. Adverse drug reaction
Used in the treatment of alcoholism by inhibiting activity of aldehyde dehydrogenase: A. Probenecid B. Antabuse C. Phenobarbital D. Aspirin
B. Antabuse
Alcohol is a specific potentiating agent when used with: A. Penicillin B. Antihistamine C. Aspirin D. Sulfonamide
B. Antihistamine
Phenobarbital-antihistamine drug combinations will result to: A. Phenobarbital metabolism is accelerated by antihistamine B. Antihistamine metabolism is accelerated by Phenobarbital C. Phenobarbital peak level ,increases D. Decreased Phenobarbital overall elimination rate
B. Antihistamine metabolism is accelerated by Phenobarbital
Alcohol is a specific potentiating agent when used with: A. Sulfonamides B. Antihistamines C. Aspirin D. Penicillin
B. Antihistamines
Drug that should not be given to children with chicken pox or flu symptoms: A. Acetaminophen B. Aspirin C. Ibuprofen D. All of these answers
B. Aspirin
Exempt prohibited drugs, except: A. Lomotil B. Benzodiazepines C. Robitussin AC syrup D. Phenergon Expectorant with Codeine
B. Benzodiazepines
Isotonic solution of this substance will cause hemolysis of RBC: A. Benzoic acid B. Boric acid C. Sodium bicarbonate D. Sodium benzoate
B. Boric acid
Drugs requiring strict precautions in their use, except: A. Methotrexate B. Codeine C. Nitrofurantoin D. Phenytoin
B. Codeine
Which of the following may be used as plasma expander? A. Sodium salts B. Dextrans C. Starches D. Calcium salts E. Prostaglandins
B. Dextrans
Reaction rate is increased most readily by: A. humidity B. High temperature C. Freezing D. Photolysis E. Hydrolysis
B. High temperature
Ferritin is a/an: A. Vitamin B. Micelle C. Emulsion D. Amino acid E. Protein
B. Micelle
Solutions that contains bacteriostatic agents: A. Cannot be tested for sterility B. Must be cultured on agar plates for sterility test C. Must be diluted beyond the bacteriostatic level for sterility tests D. Do not require a sterility test E. None of the above
B. Must be cultured on agar plates for sterility test
Urinary alkalinizer administered with sulfonamides treatment to prevent crystalluria: A. Na2CO3 B. NaHCO3 C. NaOH or KOH D. Na2CO3-10H2O
B. NaHCO3
Which of the following types drugs undergoes marked hydrolysis in the GI tract? A. Aspirin B. Penicillin G C. Acetaminophen D. hydrocortisone E. chlortetracycline
B. Penicillin G
Drugs bound to plasma proteins are considered: A. Pharmacologically active B. Pharmacologically inactive C. Free drugs B. Bioavailable drugs
B. Pharmacologically inactive
The risk of aspirin in children with fever due to viral infection: A. Gray baby syndrome B. Reye's syndrome C. Bone fraction D. AOTA
B. Reye's syndrome
A drug-induced hypersensitivity reaction caused by sulfonamides: A. Parkinson's disease B. Steven-Johnson's syndrome C. hypertension D. contact dermatitis
B. Steven-Johnson's syndrome
Freeze drying is based on: A. Pressure filtration B. Sublimation C. Polymerization D. Pasteurization E. Densification
B. Sublimation
A type of synergism in which the combined effect is equal to the additive effect of the combined drugs is termed: A. Potentiation B. Summation C. Metabolism D. Hyperactivity
B. Summation
Lidocaine HCl is not administered orally because it is: A. Ineffective by this route B. Too acidic C. too toxic by this route D. a cause of arrhythmias E. unstable
B. Too acidic
Most drugs are: A. Strong electrolytes B. Weak electrolytes C. Non-electrolytes D. Highly ionic E. None of the above
B. Weak electrolytes
Type of drug strongly bound to albumin: A. basic drugs B. acidic drugs C. alkaline drugs D. all of the above
B. acidic drugs
Theophylline when taken with high fat breakfast will result to the following: A. combination reduces the amount of theophylline B. action of theophylline is enhanced by the fat present C. combination increases the metabolism of theophylline D. both have synergistic effects
B. action of theophylline is enhanced by the fat present
The meaning of the abbreviation p.c. in the signa of a prescription: A. as necessary B. after meal C. at bedtime D. sufficient quantity
B. after meal
The most important protein to which drugs can bind in the plasma: A. lipoprotein B. albumin C. glycoprotein D. none of the above
B. albumin
Generic equivalent drugs are finished pharmaceutical products having the same ingredients, same dosage form and the same strength. They differ only in: A. generic name B. brand name C. international and non-proprietary name D. active constituents
B. brand name
The following are remedies for oxidation except: A. acid pH B. change dosage form C. addition of antioxidant D. protect from light
B. change dosage form
If the pharmacist doubts the correctness of the prescription, he should: A. consult the patient B. consult the prescriber C. consult other pharmacist D. base decision on ailment of the patient
B. consult the prescriber
The label text outside the principal display panel on the immediate container of pharmaceutical products as specified by RA 3720 contains the following information, except: A. formulation B. contraindication C. batch and/or lot number D. mode of administration
B. contraindication
Drugs that can be dispensed only through a yellow prescription pad: A. essential drugs B. dangerous drugs C. OTC products D. prescription drugs
B. dangerous drugs
These are functions of a pharmacist,except: A. drug information B. diagnosis C. counseling on medications D. monitor drug response
B. diagnosis
The transport of a substance from one part of the body to another by means of blood: A. absorption B. distribution C. metabolism D. excretion
B. distribution
Refers to the schedule of dosing (e.g. QID,10days): A. divided doses B. dosage regimen C. single dose D. total dose
B. dosage regimen
When the word otic appears on the label of the drug, the patients should be informed that the drug is applied on the: A. mouth B. ear C. eyes D. nose
B. ear
The following are true regarding incompatibilities except: A. problems arising during compounding, dispensing and drug administration B. easier to correct than to prevent C. maybe intentional or unintentional D. must be recognized by pharmacist
B. easier to correct than to prevent
The incorrect prescription that can be filled is the: A. impossible prescription B. erroneous prescription C. violative prescription D. none of the above
B. erroneous prescription
The lowering of melting point is called: A. evolution B. eutexia C. hydrolysis D. none of these
B. eutexia
The reaction between sodium bicarbonate and aspirin would result to: A. formation of precipitate B. evolution of gas C. hydrolytic changes D. invisible changes
B. evolution of gas
The date after which the product is not intended to be used: A. beyond-use date B. expiry date C. stop date D. both a&b
B. expiry date
An ADR experienced as a consequence of receiving an inappropriately high dose of the drug due to patient characteristics: A. idiosyncracy B. extension effect C. side effect D. type B
B. extension effect
A filled prescription for ethical drugs must be: A. returned to the patient B. filed for future reference C. discarded after recording D. forwarded to BFAD
B. filed for future reference
The following are patient-related predisposing factors to ADRs except: A. age B. formulation C. genetic disposition D. history of allergy
B. formulation
A suspension with the following ingredients (FeCl3,FE(OH)3, acacia, FD&C#5(orange color) and methyl paraben will reveal this manifestation: A. polymerization B. gelatinization C. cementation D. precipitation
B. gelatinization
Substances which absorb moisture from the air are called: A. effervescent powders B. hygroscopic powders C. anhydrous powders D. efflorescent powders
B. hygroscopic powders
One of the violations committed by a dispensing pharmacist is: A. informing the patient of the current list of available drugs B. imposing a particular brand or product on the buyer C. recording of prescriptions filled D. dispensing of the product according to the prescription
B. imposing a particular brand or product on the buyer
The prescription should be read and check: A. in front of the patient/customer B. in the privacy of the pharmacy C. in the counter of the botica D. none of the above
B. in the privacy of the pharmacy
The following are true about dimercaprol except: A. British anti-Lewisite B. indicated for Fe poisoning C. indicated for As poisoning D. chemical antagonist
B. indicated for Fe poisoning
In basic urine, acidic drugs are: A. un-ionized, hence reabsorbed, decrease half life B. more ionized, not reabsorbed, decrease half life C. more un-ionized, not reabsorbed, increase half-life D. un-ionized, not reabsorbed, increases elimination rate
B. more ionized, not reabsorbed, decrease half life
Which of the following is most closely related to cefazolin? A. erythromycin B. moxalactam C. carbenicillin D. gentamycin
B. moxalactam
A drug whose action is affected in a drug interaction: A. precipitant B. object drug C. interactant D. none of the above
B. object drug
Type F ADRs can occur as a result of the following except: A. antimicrobial drug resistance B. patient compliance C. counterfeit drugs D. drug instability
B. patient compliance
When suppositories containing phenol causes the vehicle to soften the melting point may be raised by adding: A. lanolin B. petrolatum C. fixed oil D. vehicle
B. petrolatum
It occurs when drugs are mixed inappropriately in syringes or infusion fluids prior to administration: A. pharmacodynamic interaction B. pharmaceutical interaction C. phamacokinetic interaction D. all of the above
B. pharmaceutical interaction
Interactions that arise with drug acting on the same receptors, sites of action or physiological system: A. pharmaceutical interactions B. pharmacodynamic interactions C. pharmacokinetic interactions D. change in body fluid and electrolyte balances
B. pharmacodynamic interactions
Failure to mix or dissolve when two or more ingredients are combined may be termed as: A. adverse reactions B. physical incompatibility C. drug precipitation D. complexation
B. physical incompatibility
Instruction and special care to avoid undesired effects an to ensure the safe and effective use of the product: A. warnings B. precautions C. contraindications D. indications
B. precautions
A written order signed by a licensed medical practitioner for medicine to be compounded by a pharmacist to meet the needs of a certain person at a particular time: A. letter B. prescription C. recommendation D. receipt
B. prescription
Part of a label that is most likely to be presented, shown or examined under customary conditions for display for retail sale: A. outer label B. principal display panel C. inner label D. label
B. principal display panel
Enzyme inhibition of coumarin can lead to: A. hypoglycemia B. profuse bleeding C. blood clotting D. convulsion
B. profuse bleeding
The conversion of an optically active form to an optically inactive form is called: A. polymorphism B. racemization C. polymerization D. enantiomorphism
B. racemization
Providing the correct medicine at the correct time, in the correct dose and the correct route of administration is called: A. primary care B. rational drug therapy C. osteopathy D. homeopathy
B. rational drug therapy
Providing the correct medicines at the right time at the right dose and using the right route of administration to the right patient is: A. primary care B. rational drug therapy C. osteopathy D. homeopathy
B. rational drug therapy
The precipitation of organic substance from a saturated solution when highly soluble salts are added is known as: A. Polymorphism B. salting dash out C. racemization D. eutexia
B. salting dash out
An associated pharmacological effect of Cholphenamine maleate: A. hypotension B. sedation C. headache D. nausea
B. sedation
Delay in gastric emptying time for the drug to reach the duodenum will_____, thereby prolonging the onset of time for the drug: A. slow the rate and extent of drug distribution B. slow the rate and extent of drug absorption C. increase the rate and extent of drug absorption D. increase the rate and extent of drug metabolism
B. slow the rate and extent of drug absorption
Dispensing directions to the pharmacist is: A. inscription B. subscription C. superscription D. transcription
B. subscription
In a prescription, the dispensing directions to the pharmacist is the: A. superscription B. subscription C. inscription D. signa
B. subscription
It forms the beginning of a direct order from the prescriber to the compounder: A. inscription B. superscription C. subscription D. errors in the written order
B. superscription
Importance of a label: A. for the sake of art B. to establish identity C. to improve elegance D. to give prominence
B. to establish identity
Anaphylaxis is a: A. type A ADR B. type B ADR C. type E ADR D. type F ADR
B. type B ADR
Idiosyncratic reactions are considered: A. type A ADR B. type B ADR C. type C ADR D. type E ADR
B. type B ADR
Indicated the quantitative range or amounts of drug that may be prescribe within the guidelines of usual medical practice: A. divided dose B. usual dosage range C. loading dose D. total dose
B. usual dosage range
Prescriber of a prescription: A. pharmacist B. veterinarian C. nurse D. medical technologist
B. veterinarian
Emulsions made with tweens are usually: A. Unstable B. w/o C. o/w D. clear E. reversible
B. w/o
For dispensing thick viscous liquids, the container should be: A. standard prescription bottles B. wide-mouthed bottles C. collapsible tubes D. dropper bottles
B. wide-mouthed bottles
A mathematical model for potentiating drug effect: A. 1+1=2 B. 1+1=3 C. 0+1=2 D. 1+1=0
C. 0+1=2
The dose of a drug is 0.5 mg/kg. What dose should be given a 6-year old child who weighs 44 lbs? A. 0.003g B. 0.033g C. 0.010g D. 0.100g E. 0.05g
C. 0.010g
What is the proof strength of a 50% (v/v) solution of alcohol? A. 25 proof B. 50 proof C. 100 proof D. 75 proof E. 150 proof
C. 100 proof
How many doses of teaspoonful each are there in a 4-fl. oz. bottle of medication? A. 10 B. 20 C. 24 D. 30
C. 24
The dose of a drug is 5mg/kg of body weight. What dose should be given to a 100-lb female patient? A. 2500 mg B. 250 mg C. 250 mg D. 44 mg E. 440 mg
C. 250 mg
How many grains are there in 5.0 g of strychnine sulfate? A. 10.4 gr B. 20.4 gr C. 77.2 gr. D. 0.99 gr.
C. 77.2 gr.
Sodium Benzoate is effective as a preservative if the pH of the preparation is: A. Above 4 B. Above 7 C. Below 4 D. Below 7
C. Below 4
A common adverse effect related to the use of aluminum antacids: A. Nausea B. Vomiting C. Constipations D. AOTA
C. Constipations
Upon exposure to air, aminophylline solution may develop: A. A gas B. A precipitate of theophylline C. Crystals of theophylline D. A straw color
C. Crystals of theophylline
Cyanocobalamin is a/an: A. Steroid B. Choline estrerase inhibitor C. Hallucinogen D. vitamin E. enzyme
C. Hallucinogen
Because it is the language of medical science throughout the world, this language is used in Rx writing: A. English B. German C. Latin D. Spanish
C. Latin
Piroxicam is a/an: A. prohibited drug B. regulated drug C. OTC drug D. any of these answers
C. OTC drug
Purified water USP may not be used in: A. Syrups B. Topical preparations C. Parenteral preparations D. Elixirs E. Effervescent solutions
C. Parenteral preparations
Which one of the following antacid products is a chemical combination of aluminum and magnesium hydroxides? A. Maalox B. Mylanta C. Riopan D. Gelusil
C. Riopan
A humectant retards: A. Bacterial growth B. Degradation C. Surface evaporation D. Spreadability E. All of the above
C. Surface evaporation
The most prevalent commercial solid dosage forms are: A. Hard capsules B. Soft gelatin capsules C. Tablets D. Bulk powders E. Divided powders
C. Tablets
When the response of a patient to one or more drugs is different in nature then that intended by the prescriber is called: A. Antagonistic incompatibility B. Chemical incompatibility C. Therapeutic incompatibility D. Physical incompatibilty
C. Therapeutic incompatibility
Any drug reaction which does not necessarily have casual relationship with the treatment is called an: A. adverse drug reaction B. therapeutic incompatibility C. adverse drug event D. none of the above
C. adverse drug event
Water is most likely to cause instability on the following drugs, except: A. penicillins B. cephalosphorins C. alkaloids D. benzodiazepines
C. alkaloids
Which of the following correctly applies to this group of drug products? Paracetamol 325mg tab, Cortal 325mg tab, Alvedon 325mg tablet: A. all are generically equivalent B. all are in brand names C. all are non-prescription drug D. all are prescription drug
C. all are non-prescription drug
Zephiran is used in ophthalmic solution as: A. suspending agent B. surfactant C. anti-microbial agent D. anti-microbial agent and surfactant
C. anti-microbial agent
Are added to drug formulations to prevent or reduce oxidation: A. complexing agents B. surfactants C. antioxidants D. additives
C. antioxidants
When dispensing prepared dosage forms, the pharmacist may use which of the following dose equivalents? A. exact equivalent B. exact dose C. approximate dose D. a&b
C. approximate dose
A synonym for vitamin C is: A. Riboflavin B. tocopherol C. ascorbic acid D. cyanocobalamin E. thiamine
C. ascorbic acid
A remedy for tablet granulations containing vitamin C: A. prepare by dry granulation B. used pre-coated ascorbic acid granules C. both a&b D. none
C. both a&b
Chloramphenicol can lead to this untoward drug reaction: A. agranulocytosis B. Gray syndrome C. both a&b D. none of the above
C. both a&b
Oral antihistamines exhibit the following side effect: A. drowsiness B. sleepiness C. both a&b D. anemia
C. both a&b
The following condition/s will amplify the activity of cardiac glycosides: A. hypercalcemia B. hypokalemia C. both a&b D. none of the above
C. both a&b
Oxidizing agents are incompatible with reducing agents. This is a: A. physical incompatibility B. therapeutic incompatibility C. chemical incompatibility D. both a and b
C. chemical incompatibility
The two major properties of drug that are usually modified by complexation are: A. Odor and taste B. Taste and solubility C. chemical structure and solubility D. chemical structure and stability E. stability and solubility
C. chemical structure and solubility
A drug that increases the anticoagulant action of warfarin because of its metabolite competes with the anticoagulant for plasma protein blinding sites: A. Tolbutamide B. aspirin C. chloral hydrate D. diazepam
C. chloral hydrate
If there's doubt in legibility of prescription, the pharmacist should: A. decide based on patient's ailment B. make an educated guess C. consult the prescriber D. consult MIM
C. consult the prescriber
The supply of medicine to an individual patient in accordance to the prescription given by the physician: A. compounding B. formulation C. dispensing D. none of the above
C. dispensing
Generic dispensing means: A. dispensing drugs with generic names only B. dispensing with correct prescription C. dispensing customer's choice from generically equivalent drugs D. dispensing drugs in proper container
C. dispensing customer's choice from generically equivalent drugs
Citric acid, atropine sulfate and ferrous sulfate are classified as: A. eutectic mixtures B. deliquescent substances C. efflorescent substances D. polymorphs
C. efflorescent substances
A prescription should be refused when: A. patient is terribly sick B. there is no available delivery service C. essential information is missing D. it is not signed by the pharmacist
C. essential information is missing
The following responses belong to type B adverse reactions, except A. Allergy of Cefotaxime B. A plastic anemia in patients taking chloramphenicol C. facial abnormalities in babies born to alcoholic mothers D. peripheral neuritis in a British missionary III with tuberculosis
C. facial abnormalities in babies born to alcoholic mothers
Examples of co-solvents: A. water, buthanol B. alcohol, mineral oil C. glycols, sorbitol, glycerol D. acetone, water, alcohol
C. glycols, sorbitol, glycerol
The following drugs often precipitate an interaction when administered with a second drug, except: A. Sedation B. headache C. hemolytic anemia D. hypokalemia
C. hemolytic anemia
This container is impervious to air and other gases under ordinary conditions of handling storage and transport: A. airtight container B. security closed C. hermetically sealed D. child-resistant container
C. hermetically sealed
The abbreviations SOS on prescriptions means: A. At once B. freely C. if needed D. do not repeat E. on alternate days
C. if needed
Occurs immediately upon compounding like presence of precipitate; effervescence of color changes: A. minor incompatibility B. delayed incompatibility C. immediate incompatibility D. major incompatibility
C. immediate incompatibility
A STAT order means the drug has to be administered: A. as needed by the patient B. at the hour of sleep C. immediately D. before surgery
C. immediately
A prescription where the generic name does not correspond to the brand name: A. violative Rx B. erroneous Rx C. impossible Rx D. yellow DDB RX
C. impossible Rx
During drug interaction, the affected drug may become more active resulting to the following, except: A. increase drug activity B. longer therapeutic action C. less effective D. toxicity
C. less effective
Acidic group of amino acids responsible for binding basic drugs, except: A. glutamic B. aspartic C. lysine D. tyrosine
C. lysine
Used as pharmaceutical packaging materials include aluminum, tin and tin-coated lead: A. glass B. plastics C. metals D. paperboards
C. metals
Which of these drug products require a physician's prescription: A. aspirin 325 mg tab B. paracetamol 500 mg tab C. nubain 10mg/vial D. both b&c
C. nubain 10mg/vial
Side effect of streptomycin: A. headache B. dryness of the mouth C. ototoxicity D. none of the above
C. ototoxicity
NPO means: A. patient should be given drugs after meals B. patient should be given drugs before meals C. patient should not be given anything by mouth D. patient should be left undisturbed
C. patient should not be given anything by mouth
Degradation of drugs or excipient molecules can be brought about by light, either room light or sunlight: A. solvolysis B. oxidation C. photolysis D. polymerization
C. photolysis
Remedy when a solid substance fails to dissolve in a liquid: A. addition of an inert ingredients B. prepare an emulsion C. prepare a suspension D. dispensing the ingredients separately
C. prepare a suspension
which of the following types of tissues frequently store drugs? A. Fatty tissue B. muscle tissue C. protein tissue D. a&b E. a and c
C. protein tissue
Corticosteroids are frequently given with antacids to: A. enhance absorption B. slow absorption C. reduce ulceration and bleeding D. increase the rate of distribution
C. reduce ulceration and bleeding
Decreased urinary recycling, increases elimination rate constant hence: A. increases half life B. longer duration of pharmacologic response C. shortens duration of pharmacologic response D. increases therapeutic concentration in the body
C. shortens duration of pharmacologic response
Diuretics tend to enhance lithium salt toxicity due to: A. direct drug interaction B. potassium depletion C. sodium depletion D. increased solubility of the lithium salts
C. sodium depletion
Extacy exhibits this type of ADR: A. type A B. type B C. type C D. type D
C. type C
Enzyme induction of Phenobarbital with oral contraceptives can lead to: A. decreased Phenobarbital actions B. increased oral contraceptives action C. unreliable contraception D. none of the above
C. unreliable contraception
General corrections of incompatibilities include all of the following, except: A. separation of immiscible liquids B. change of vehicle C. use of a different brand D. substitution of ingredients
C. use of a different brand
The "NO SUBSTITUTION" instruction is seen on: A. erroneous prescription B. impossible prescription C. violative prescription D. any of the above
C. violative prescription
When an oxidizing agent is triturated in a mortar with a reducing agent, this would likely result to: A. formation of damp mass B. discoloration of powders C. violent explosion D. volatilization of some of the ingredients
C. violent explosion
This drug inhibits the vitamin K dependent synthesis of clotting factors II, VII, IX and X: A. tetracycline B. diphenhydramine C. warfarin D. aspirin
C. warfarin
Consequence of adverse drug reactions: A. Increased mortality B. Prolonged hospital stay C. Increased cost therapy D. AOTA
D. AOTA
Tetracycline tend to form complexes with: A. Iron salts B. Magnesium salts C. Calcium Salts D. AOTA
D. AOTA
Which of the following factors may make it necessary to give lower doses of drugs to geriatric patients? A. Reduced enzyme activity B. Reduced kidney function C. Enhanced absorption D. AOTA
D. AOTA
Sudden withdrawal of steroids can result in: A. anemia B. hypertension C. Parkinson's disease D. Addison's disease
D. Addison's disease
Gums are used in tableting primarily as: A. Disintegrant B. Glidants C. Lubricants D. Binding agents E. Both b and c
D. Binding agents
The ingestion of a alcoholic drinks while on analgesic or sedative therapy represents a commonly encountered drug interaction that may result in: A. Tolerance B. Antagonism C. Excessive CNS stimulation D. Excessive CNS Depression
D. Excessive CNS Depression
To prevent errors, the Pharmacist uses: A. His knowledge of Pharmacognosy B. His knowledge of Chemistry C. His broad knowledge of drugs D. His knowledge of diseases
D. His knowledge of diseases
Chemical incompatibility includes all of the ff except: A. Racemization B. Implosion C. Cementation D. Liquefaction
D. Liquefaction
Pharmacist should caution patients who are taking niacin that this drug: A. Stains the urine bright red B. Causes ringing in the ears C. Causes muscular weakness D. Should be taken with meals
D. Should be taken with meals
Substance used as a test for, liver function by measuring the amount of hippuric acid in urine: A. Sodium borate B. Aspirin C. Sodium salicylate D. Sodium benzoate
D. Sodium benzoate
The combined action of two or more drugs which results in an enhancement or intensifying effect is termed: A. Metabolism B. Antagonism C. Stimulation D. Synergism
D. Synergism
Valium and Tagamet combination will not result to one from the following: A. Tagamet delay elimination of anti-anxiety agent B. Increased sedation and dizziness C. Blood levels of anti-anxiety drug increased D. Valium increases the metabolism of theophylline
D. Valium increases the metabolism of theophylline
Which of the following is not a naturally occurring emulsifier? A. Acacia B. Cholesterol C. Gelatin D. Veegum E. Tragacanth
D. Veegum
Cold preparations when taken in large closes may interact with: A. Sedatives B. guaiafenisin C. MAOIs D. a and c
D. a and c
Precipitation can be: A. physical incompatibility B. chemical incompatibility C. adverse drug reaction D. a/b
D. a/b
Most common side effects of erythromycin therapy? A. Anaphylaxis B. ototoxcicity C. bleeding D. abdominal cramps
D. abdominal cramps
Displacement of plasma-protein bound drug such as in Warfarin phenylbutazone interactions results in: A. hemorrhage B. increased concentration of Warfarin C. decreased activity of Warfarin D. all
D. all
Tobacco and cigarettes are potent enzyme inducers. As a consequence: A. one needs to increase dose of drug B. this leads to drug tolerance C. this is an ADR D. all
D. all
Alkaline salts like Potassium penicillin when placed in an acidic solution can result in: A. conversion into free acid B. precipitation of penicillin C. insolubility D. all of the above
D. all of the above
In pricing prescription, the pharmacist must consider: A. cost of ingredients B. professional fee C. percentage mark-up D. all of the above
D. all of the above
In pricing the prescription, the pharmacist must consider: A.cost of ingredients B. professional fee C. percentage mark-up D. all of the above
D. all of the above
Monoamine oxidase inhibitors (MAOI) and foods rich in tyramine like cheese will lead to: A. accumulation of pressor amines B. increase in blood pressure C. non-metabolism of tyramine D. all of the above
D. all of the above
Oxidation is a: A. lost of electron B. dehydrogenation C. cause of drug instability D. all of the above
D. all of the above
Source/s of information regarding incompatibilities: A. Remington B. USP C. Product inserts D. all of the above
D. all of the above
The following is/are characteristic/s of side effects: A. dose dependent B. predictable C. associated pharmacological effect D. all of the above
D. all of the above
These reactions belong to Augmented type (type A): A. Extension effect B. allergy C. side effect D. all of the above
D. all of the above
To calculate a loading dose, one must first determine: A. body clearance B. fraction protein bound C. volume of distribution D. all of the above
D. all of the above
Traditional classification of adverse drug reactions: A. Side effect B. extension effect C. allergy D. all of the above
D. all of the above
Poor patient compliance with prescription instruction is usually due to the following except: A. patient understood pharmacist's instruction poorly B. pharmacist has poor communication skills C. inadequate time of pharmacist for patient counseling D. any of the above
D. any of the above
Combinations liable to produce therapeutic incompatibilities when administered at the same time, except: A. sedatives and stimulants B. tannins and aloins C. caffeine and chloral hydrate D. aspirin and warfarin
D. aspirin and warfarin
The following type/s of incompatibility may be dispensed: A. intentional incompatibility B. unintentional incompatibility C. delayed chemical incompatibility but within shelf-life of the product D. both a&c
D. both a&c
Acacia in the presence of Bismuth salts can form a "cake" at the bottom of the container. This manifestation is known as: A. gelatinization B. hydrolysis C. emulsification D. cementation
D. cementation
An anionic exchange resin intended to bind acids, cholesterol metabolites and co-administered drugs: A. chloramphenicol B. cholesterol precursor C. tetracycline D. colestyramine
D. colestyramine
Probenecid and Penicillin exhibits this type of interaction: A. enzyme induction B. enzyme inhibition C. alteration in gastric emptying D. competition for tubular secretion
D. competition for tubular secretion
Combination of NaHCO3 with an organic acid (citric or tartaric acid) will result in: A. precipitation B. color changes C. oxidation D. effervescence
D. effervescence
Mixtures of phenolic, aldehydes, ketonic compounds and alcohols are examples of: A. insoluble substances B. hydroscopic substances C. delinquent substances D. eutectic mixtures
D. eutectic mixtures
Major pathway of excretion are via the kidney into the urine and via the liver into the: A. bile B. urine C. alveolar air D. feces
D. feces
Factors that tend to reduce stomach contraction and gastric emptying rate, except: A. consumption of meals high in fat B. patient lying on left side C. depression D. hyperthyroidism
D. hyperthyroidism
The following are possible remedies for liquefication of solid substances, except: A. triturate separately and mix by tumbling B. add adsorbents to liquid combination C. dispense powder separately D. incorporate cotton in packaging
D. incorporate cotton in packaging
Increased urinary recycling increases half life hence, except: A. decreases elimination rate constant B. blood level rise and persist longer C. danger of toxicity in multiple dosing D. increases elimination rate constant
D. increases elimination rate constant
The approved clinical use of the product based on substantial evidence of the efficacy and safety of the drug: A. warning B. formulation C. pharmacologic category D. indication
D. indication
Which statement is incorrect regarding interaction involving tyramine containing substance and MAO inhibitor? A. inhibition of MAO result in the accumulation of large amounts of norepinephrine B. decrease ion the rate of intracellular metabolism C. large amount of norepinephrine can cause severe headache and hypertension D. large amount of stored norepinephrine can cause hypotensive crisis
D. large amount of stored norepinephrine can cause hypotensive crisis
Liquefaction of crystalline salt occurs on trituration is due to: A. addition of water B. addition of other liquid ingredient C. absorption of moisture from the air D. liberation of water of crystallization
D. liberation of water of crystallization
Clindamycin is closely related to which if the following in effective spectrum? A. Chloramphenicol B. Lincomycin C. prednisolone D. methylprednisone E. dexamethasone
D. methylprednisone
Aspirin combines with Phenylsalicylate resulting to: A. Melting B. non-homogenous mixture C. turbid solution D. moist mass
D. moist mass
When dispensing a compounded prescription, these information must be written on the label except: A. indications B. name and strength of actives C. name of the manufacturer D. name of physician
D. name of physician
Factors that reduced binding capacity to albumin, except: A. liver impairment B. smoking C. during pregnancy D. neonates patient
D. neonates patient
Chloramphenicol palmitate exist in 3 different polymorphs, each differ in the following properties except: A. solubility B. free energy C. melting point D. none of the above
D. none of the above
Important characteristics of idiosyncratic drug reactions, except: A. congenital hypersensitivities B. genetic or hereditary in origin C. metabolic abnormality D. none of the above
D. none of the above
The following are true regarding excretion of acidic drugs except: A. exist in the ionized state in alkaline urine B. exist in the non-ionized form in acidic urine C. acidic urine increases drug action D. none of the above
D. none of the above
Vanishing creams are classified as: A. Oleaginous B. Absorption bases C. Water-soluble bases D. o/w bases E. w/o bases
D. o/w bases
The antiseptic property of hydrogen peroxide is due to: A. ozone B. acetanilide C. peroxidase D. oxygen
D. oxygen
Pharmacokinetically, enzyme induction will result to the following except: A. peak level decreases B. accelerated metabolism C. increased overall elimination rate D. pharmacological responses are decreased
D. pharmacological responses are decreased
Compounding is concerned with: A. supply of a medicine B. preparation and distribution of drugs C. order of medicine D. preparation of medicine
D. preparation of medicine
The conversion of optically active drug with one chiral center into an optically inactive isomer: A. polymorphism B. enantiomers C. epimerization D. racemization
D. racemization
Drug products that are considered prohibited, except: A. Heroin and morphine B. coca leaf and its derivative cocaine C. mescaline and Indian hemp D. secobarbital
D. secobarbital
Optimum absorption takes place in the: A. gastrointestinal tract B. receptor C. stomach D. small intestine
D. small intestine
Activated charcoal is used in some antidotes because of which of its properties? A. Neutralizing B. emetic C. absorptive D. stabilizing
D. stabilizing
An impossible prescription is described by the following except: A. only the generic name is written but not legible B. both generic and brand names are not legible C. the generic name does not correspond to the brand name D. the generic name is not legible and the brand is written legibly
D. the generic name is not legible and the brand is written legibly
Teratogenicity is a/an: A. type A ADR B. type B ADR C. type C ADR D. type D ADR
D. type D ADR
The following are the physiologic effects of food on drug action except: A. reduces gastric emptying rate B. milk reduces absorption of tetracycline C. tea increases absorption of paracetamol D. vegetables potentiate anticoagulants
D. vegetables potentiate anticoagulants
Surface active agents tend to enhance absorption due to: A. Their effects on biological membrane B. Their effects on the dissolution rate of drugs C. Reduction of interfacial tension D. B and c only E. A, b and c
E. A, b and c
Tetracycline tend to form complexes with: A. Calcium ions B. Magnesium ions C. Aluminum ions D. Iron ions E. All of the above
E. All of the above
Salicylic acid is used primarily as : A. Analgesic B. Anti pyretic C. Cough supressant D. Uricosuric agent E. Keratolytic agent
E. Keratolytic agent
pH is: A. not temperature B. a measure of acidity C. the same as pOH D. high of acids E. none of the above
E. none of the above
In radiopharmacy, the term "rem" means: A. Radiations per millisecond B. Radiations per minute C. Roentgen-equivalent-man D. external roentgens per minute E. roentgen exposure per minute
E. roentgen exposure per minute