Drugs Chapter 10 opiates

CNS depressants and opiates can synergize in a way that can be lethal. TrueFalse

A

Chapter 10 of the textbook, often refers to prescription drugs as _________, when strictly speaking they should be referred to as ________, in keeping with current terminology for anything that is not found in _______. A. opiates; opioids; opium B. opioids; opium; opiates C. opiates; opium; papaver somniferum D. opiates; synthetic opiates; opium

A

Heroin was marketed by makers of aspirin. TrueFalse

A

Opiate withdrawal symptoms are best characterized as A. flu-like in nature B. nearly always fatal C. convulsions and seizures D. mild and unimportant

A

The region of _________ was historically the largest supplier of opium, prior to the emergence of _________ as the world's leading supplier late in the 20th century? A. Southeast Asia; Afghanistan B. Colombia; Southeast Asia C. Afghanistan; Mexico D. Central and South America; Afghanistan

A

Which of the following drugs is unlikely to produce analgesia? A. naloxone B. meperidine C. fentanyl D. codeine

A

Which of the following is NOT a response to opiate administration? A. yawning and pupil dilation B. constipation C. analgesia D. hypothermia

A

With regard to opiates, the Harrison Act went through a number of modifications that A. All of these are correct B. eventually stopped the prescribing of heroin for medical use C. stimulated the emergence of a black market that catered for addicts who would have been prescribed heroin by physicians D. led to heroin becoming an illicit drug controlled by organized crime and affecting low income groups in urban areas

A

"Chasing the dragon" refers to ___________ heroin. A. eating B. smoking C. snorting D. injecting

B

An early use for heroin was as a treatment for: A. cancer B. coughs C. addiction to marijuana D. dengue fever

B

Endorphin release is produced by _____. A. pain B. all of the options listed C. stress D. acupuncture

B

Heroin withdrawal produces A. cold-like symptoms (runny nose, teary eyes) B. all of these are true C. diarrhea D. piloerection (goose bumps)

B

If equivalent doses of morphine and heroin were administered, they would each cross the blood-brain barrier at an equal rate TrueFalse

B

Only about 50% of heroin is excreted from the body after a few days. TrueFalse

B

The "Opium Wars" of the 19th century were between Great Britain and: A. India B. China C. Afghanistan D. Hong Kong

B

The origins of the current opioid epidemic are generally attributed to the abuse of ________, which contained ________. A. Percodan; oxycodone B. Oxycontin; oxycodone C. Oxycodone; oxycontin D. Oxycontin; percodan

B

This drug is becoming popular as an alternative to methadone in the treatment of opiate addiction. A. Naloxone B. Buprenorphine C. Vicodin D. Sublimaze

B

Tolerance to opiates occurs in humans but not in rhesus monkeys. TrueFalse

B

Which of the following correctly provides the relative potency for the indicated drug, when compared to morphine? A. Codeine, less potent B. All of these are correct C. Heroin, about twice as potent D. Oxycodone, 1.5 times more potent E. Fentanyl, 100 times more potent

B

Which of the following is true of opiate withdrawal? A. appetite increases significantly B. symptoms peak in about 48 to 72 hrs. C. all of these are true D. symptoms can be treated with alcohol

B

Which of the following likely used opium before the Romans? A. The Greeks B. the Sumerians and Assyrians C. the Egyptians D. the Inca people of South America

B

Which of the following will bind in the brain the same receptor as morphine ? A. acetylcholine B. endorphins C. noradrenalin D. dopamine E. serotonin

B

Endorphins are thought to be involved with which of the following functions? A. sleep B. fear C. pain relief D. none of the options listed

C

Pain relief produced without a loss of consciousness is called A. akinesia B. anorexia C. analgesia D. anesthesia

C

The major active chemical in opium is ____________, and has an effect that is ______ more potent than crude opium. A. thebaine; ten times B. heroin; two times C. morphine; ten times D. morphine; two times

C

Use of heroin or morphine is known to A. reduce sexual drive B. all of these are correct C. impair learning and memory D. induce impotence E. impair social interactions

C

What is the main difference between morphine and heroin? A. Heroin takes much longer to metabolize. B. Morphine is more potent than heroin. C. Heroin more readily penetrates the blood-brain barrier. D. Morphine is more lipid-soluble E. all of the options listed

C

Which of the following contains a partial opiate agonist and opiate antagonist? A. buprenorphine B. all of these drugs contain a combination of agonist and antagonist effects C. suboxone D. tramadol E. tapentadol

C

Which of the following drugs is the most potent pain reliever and an increasing threat in the current opiate drug epidemic? A. heroin B. morphine C. fentanyl D. Oxycontin

C

Which of the following is a common opiate effect? A. pupil constriction B. lowered body temperature C. all of these are opiate effects D. respiratory depression

C

Which of the following is a major risk associated with the sharing of needles used to deliver heroin intravenously? A. overdose B. respiratory distress C. infection with AIDS, hepatitis or other needle-borne diseases D. bone marrow damage

C

Which of the following is a natural substance that will directly compete with naloxone for receptors in the brain? A. oxycodone B. fentanyl C. endorphin D. all of these

C

Opium is derived from the plant ______ and is typically used A. psilocybin mushrooms; by oral consumption B. Cannabis sativa; by smoking C. Papaver somniferum; by injection D. Papaver somniferum; orally or by smoking

D

Purdue Pharma was sued for A. misrepresenting the abuse potential of Percodan B. selling designer heroin C. marketing a low-dose formulation of Oxycontin, when a high-dose formulation should have been available to patients with chronic pain D. stating that Oxycontin had low abuse potential

D

The study by Hser et al (2001) A. found that in the USA, there were 33,000 deaths over the past 33 years that were due to heroin overdose B. reported that heroin addiction rates declined throughout the 1990s, but increased substantially from 2000 to the present C. all of these are true D. followed heroin addicts over several decades, and found that half of them died, a death rate substantially higher than the general population that were of a similar age

D

Which of the following is used as a treatment for excessive coughing? A. morphine B. methadone C. barbiturates D. dextromethorphan

D

____________ is a drug that was designed for treatment of severe pain and involves time-release of high doses of ________ that could reduce pain for 12 hours. A. Vicodin; oxycodone B. Dilaudid; Oxycontin C. Demerol; percodan D. Oxycontin; oxycodone

D