Isoniazid

during anti tb therapy with isoniazid a patient received another prescription for pyridoxine. which statement by the nurse best explains the rationale for this second med? A. this vitamins will help to improve your energy levels B. this vitamins helps to prevent neurologic adverse effects C. this vitamin works to protect her heart from toxic effects D. this vitamins helps to reduce gastrointestinal adverse effects

B this vitamin helps to prevent neurologic adverse effects

the nurse is monitoring for liver toxicity in a patient who has been receiving long term isoniazid therapy. Manifestations of liver toxicity include (select all that apply) A. orange discoloration of sweat and tears B. darken urine C. dizziness D. fatigue E. visual disturbances F. jaundice

B. darken urine D. fatigue F. jaundice

After diagnosing a client with pulmonary tuberculosis, the physician tells family members that they must receive isoniazid (INH [Laniazid]) as prophylaxis against tuberculosis. The client's teenage daughter asks the nurse how long the drug must be taken. What is the usual duration of prophylactic isoniazid therapy? a) 3 to 5 days b) 1 to 3 weeks c) 2 to 4 months d) 6 to 12 months

D

Before discharge, the nurse is reviewing a client's prescribed medication regimen for tuberculosis (TB). The client asks the nurse why pyridoxine (vitamin B6) has been prescribed while continuing to take isoniazid (Nydrazid) to treat TB. What is the nurse's best response? A. "Multidrug therapy is necessary to prevent the occurrence of resistant bacteria." B. "You really should not be on that drug. I will check with the health care provider." C. "Pyridoxine is another antitubercular drug that will work synergistically with the isoniazid." D. "Pyridoxine will help prevent numbness, and tingling that can occur secondary to the isoniazid."

D. "Pyridoxine will help prevent numbness, and tingling that can occur secondary to the isoniazid."

What instruction should the nurse include for a client prescribed rifampin (Rifadin) and isoniazid (Nydrazid) prophylactically secondary to TB exposure? A. Advise that these drugs will only need to be taken for 7 to 10 days. B. Remind that sunscreen is not needed during outdoor activities. C. Explain that isoniazid may decrease blood serum glucose in susceptible people. D. Emphasize that oral contraceptives become ineffective when given with rifampin.

D. Emphasize that oral contraceptives become ineffective when given with rifampin.

When assessing for adverse effects to Rifamate (combination isoniazid and rifampin), the nurse would monitor which laboratory values? (Select all that apply.) A. Cholesterol B. Uric acid levels C. Sputum cultures D. Liver function tests E. Complete blood cell count

D. Liver function tests E. Complete blood cell count

The nurse anticipates a prescription for vitamin supplementation for a client who is receiving isoniazid (Nydrazid) therapy. What vitamin supplement is usually prescribed with isoniazid? A. Folate B. Calcium C. Vitamin E D. Vitamin B6

D. Vitamin B6

The nurse cares for a patient with tuberculosis who is taking isoniazid and rifampin. About which data found in the patient's health history is the nurse most concerned? 1. Hepatitis B. 2Asthma attacks 3. Rheumatic fever 4. Allergy to penicillin

Hepatitis BIsoniazid (INH) and rifampin are tuberculosis medications that are metabolized in the liver and are extremely toxic. They are contraindicated in the patient with a history of liver disease, including any form of hepatitis. A history of asthma, rheumatic fever, or allergy to penicillin is not a contraindication to the administration of INH and rifampin.

When providing health education to a client prescribed isoniazid, the nurse should emphasize the need to avoid which of the following?

alcohol

The physician determines that a client has been exposed to someone with tuberculosis. The nurse expects the physician to order which of the following? a) Daily oral doses of isoniazid (Nydrazid) and rifampin (Rifadin) for 6 months to 2 years b) Isolation until 24 hours after antitubercular therapy begins c) Nothing, until signs of active disease arise d) Daily doses of isoniazid, 300 mg for 6 months to 1 year

d) Daily doses of isoniazid, 300 mg for 6 months to 1 year

A woman whose husband was recently diagnosed with active pulmonary tuberculosis (TB) is a tuberculin skin test converter. Management of her care would include: a) scheduling her for annual tuberculin skin testing. b) placing her in quarantine until sputum cultures are negative. c) gathering a list of persons with whom she has had recent contact. d) advising her to begin prophylactic therapy with isoniazid (INH).

d) advising her to begin prophylactic therapy with isoniazid (INH).

What is isoniazid's mechanism of action?

inhibits cell wall formation - take on empty stomach - hepatotoxicity and nephrotoxicity - tingling in hands and feet - NO ETOH

What adverse effect would most likely necessitate discontinuing treatment with isoniazid?

jaundice

During treatment with isoniazid, the nurse should plan to meet a specific need by providing the client with what supplement?

liver enzymes