Multiple endocrine neoplasia

Mucosal neuromas, medullary carcinoma of the thyroid, pheochromocytoma, and marfanoid body habitus are all associated with which multiple endocrine neoplasia type?

Mucosal neuromas, medullary carcinoma of the thyroid, pheochromocytoma, and marfanoid body habitus are all associated with multiple endocrine neoplasia 2B.

Parathyroid tumors, pituitary adenomas, and pancreatic endocrine tumors are all associated with?

Parathyroid tumors, pituitary adenomas, and pancreatic endocrine tumors are all associated with multiple endocrine neoplasia 1 syndrome. Remember 3 P's for MEN 1: Pituitary, Parathyroid, Pancreatic.

How should patients with pheochromocytoma be treated?

Patients with pheochromocytoma should be treated first with a(n) alpha-blocker and then a beta-blocker prior to surgery

What is the inheritance pattern for MEN syndromes?

Autosomal dominant

What is believed to explain the pathogenesis of multiple endocrine neoplasia type 2?

A point mutation in the RET oncogene is believed to explain the pathogenesis of multiple endocrine neoplasia type 2

What are the MEN syndromes?

Familial syndromes associated with multiple endocrine tumors

What biochemical testing may be recommended to monitor for recurrent or metastatic pheochromocytomas and paragangliomas?

Lifelong annual biochemical testing for plasma and urine levels of metanephrines may be recommended to monitor for recurrent or metastatic pheochromocytomas and paragangliomas.

What is MEN 2A associated with?

MEN 2A is associated with parathyroid hyperplasia, medullary thyroid carcinoma, and pheochromocytoma. Remember MEN 2A = 2 P's: Parathyroids and Pheochromocytoma.

What is associated with marfanoid habitus and mutation in RET gene?

MEN 2B is associated with marfanoid habitus and mutation in RET gene

What is MEN 2B associated with?

MEN 2B is associated with medullary thyroid carcinoma, pheochromocytoma, and mucosal neuromas. MEN 2B = 1 P: Pheochromocytoma

Which MEN is associated with multiple neuromas on the lips and mouth?

MEN 2B is associated with multiple neuromas on the lips and mouth

What do medullary carcinomas of the thyroid, which are seen in multiple endocrine neoplasia 2A and 2B, secrete?

Medullary carcinomas of the thyroid, which are seen in multiple endocrine neoplasia 2A and 2B, secrete calcitonin

How is the recurrence of medullary thyroid carcinoma monitored?

Recurrence of medullary thyroid carcinoma is monitored for with calcitonin, CEA, and provocative calcitonin testing