NUR 325: pharmacological concepts

the peak is the amount of time the drug

needs to reach its highest effective concentration

a patient taking SMZ/TMP asks the nurse what the name means. the nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

sulfamethoxazole has a synergistic effect with trimethoprim against gram-positive and gram-negative organisms.

the following terms either describe a Generic or a Brand/Trade name, place the descriptor into the appropriate category

Generic: safest way to refer to a drug not capitalized name given by the company that developed the drug Brand/Trade: commercial name capitalized

when two drugs given together have an effect equal to the sum of their respective effects, the interaction is known as:

additive

an unintended effect of the drug is known as a(n)

adverse effect

when a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):

agonist

when performing an assessment to determine which medications can be used, which of the following elements is most important?

allergies

which of the following circumstances will increase the rate of drug absorption for a subcutaneous injection?

large muscle mass

which organ does drug metabolism usually occur in?

liver

a patient requires a high dose of a new antihypertensive medication because the new medication has a significant first-pass effect. What does this mean?

the medication is extensively metabolized in the patient's liver.