*Pharm Chapter 12 Quiz

Cromolyn sodium is effective in preventing bronchospasm by enhancing mast cell degranulation. blocking cholinergic receptor sites. stimulating R2-adrenergic sites. inhibiting mast cell degranulation.

inhibiting mast cell degranulation

Singulair can be administered to which of the following patient populations? 1. Adults and adolescents 15 years or older 2. Pediatric patients 6 to 14 years 3. Pediatric patients 2 to 5 years 4. Pediatric patients 12 to 23 months 5. Pediatric patients 6 to 23 months

1. Adults and adolescents 15 years or older 2. Pediatric patients 6 to 14 years 3. Pediatric patients 2 to 5 years 4. Pediatric patients 12 to 23 months 5. Pediatric patients 6 to 23 months

What is the mechanism of action for Singulair? Leukotriene receptor antagonist Monoclonal antibodies Leukotriene receptor agonist 5-LO inhibitor

Leukotriene receptor antagonist

Cromolyn sodium is available in what form? Nebulizer solution MDI Tablet Nasal spray

Nebulizer solution

Which of the following is a monoclonal antibody used to treat asthma? Zileuton Zafirlukast Montelukast Omalizumab

Omalizumab

Zach is a 14 year old with complaints of shortness of breath and wheezing when working out. He currently takes albuterol and theophylline. What medication may help with his symptoms? Accolate Xolair Singulair Cromolyn

Singulair

The only antileukotriene agent currently approved for use in patients younger than 5 years of age is? Accolate. Singulair. zafirlukast. Xolair.

Singulair.

Allergic inflammation of the airway is the product of an immune response, and the ________________ plays a central role in attracting mast cells and eosinophils. T lymphocyte B lymphocyte A and B Neither A nor B

T lymphocyte

Zileuton is administered by nebulizer. DPI. MDI. tablet.

tablet.

Leukotrienes exhibit which of the following effects? 1. Increased mucus secretion 2. Inhibition of normal ciliary action 3. Increased airway edema 4. Bronchoconstriction 5. Recruitment of other inflammatory cells into airways

1. Increased mucus secretion 2. Inhibition of normal ciliary action 3. Increased airway edema 4. Bronchoconstriction 5. Recruitment of other inflammatory cells into airways

Zileuton interacts with which of the following respiratory care drugs? 1. Theophylline 2. Albuterol 3. Warfarin 4. Ipratropium bromide 5. Beclomethasone

1. Theophylline 3. Warfarin

Which of the following are antileukotriene agents? 1. Zafirlukast 2. Zileuton 3. Cromolyn sodium 4. Montelukast

1. Zafirlukast 2. Zileuton 4. Montelukast

After a patient begins using cromolyn sodium, how long may it take before clinical improvement in the patient's symptoms is seen? 24 hours 2 to 4 weeks 4 to 6 days 1 to 3 months

2 to 4 weeks

The usual dose of nebulized cromolyn sodium is 20 mg four times per day. 30 mg three times per day. 80 mg three times per day. 10 mg four times per day.

20 mg four times per day.

A 22-year-old patient is experiencing an acute exacerbation of her asthma and is complaining of wheezing and shortness of breath. Which is the most appropriate medication to help relieve her symptoms? Cromolyn sodium Omalizumab Zileuton Albuterol

Albuterol

What is the clinical indication for use of antileukotriene drug therapy, such as montelukast, in asthma? As an alternative to inhaled steroids As a mast cell stabilizer As a rescue bronchodilator in step 1 asthma As a long-acting bronchodilator in step 3 asthma

As an alternative to inhaled steroids

Bobby is in a sickle cell crisis. Along with his pain medications, he received a medication via inhalation. His mother asks you if you know what the medication was. What is one possibility? Relenza Albuterol Combivent Cromolyn

Cromolyn

Which of the following agents is considered a mast cell stabilizer? Cromolyn sodium Zafirlukast Zileuton Montelukast

Cromolyn sodium

Which of the following is an advantage to the use of antileukotriene agents? Multiple ways of administration Effective in more than 90% of patients All formulations are available for pediatric use No interaction with inhaled steroids

Effective in more than 90% of patients

Which type of asthma is associated with allergic reactions? Extrinsic Intrinsic Chronic Acute

Extrinsic

Which of the following nonsteroidal antiasthma agents is formulated as a subcutaneous injection? Xolair Zafirlukast Montelukast Zileuton

Xolair

Accolate is the brand name for which medication? Omalizumab Zafirlukast Montelukast Zileuton

Zafirlukast

Mast cells are? agents that block the inflammatory response in asthma. agents used prophylactically to treat the inflammatory response in asthma. connective tissue cells that contain heparin and histamine. chemical mediators that cause inflammation.

connective tissue cells that contain heparin and histamine.

Nonsteroidal antiasthma drugs are relievers. controllers. R2 antagonists. antiinfectives.

controllers.

Zafirlukast is a ? leukotriene receptor stimulator. leukotriene receptor antagonist. B adrenergic. corticosteroid.

leukotriene receptor antagonist.

The most commonly reported side effect of cromolyn sodium is headache. diarrhea. nasal congestion. pneumonia.

nasal congestion.

The general indication for clinical use of nonsteroidal antiasthma agents is short-term control of bronchospasm. control of severe asthma attack. long-term control of bronchospasm. prophylactic management of mild persistent asthma.

prophylactic management of mild persistent asthma.