Quiz 14

Staphylococcus

Alexander Fleming first observed a mold (now known as Penicillium notatum) that was able to inhibit which organism

helminth

Benzimidazoles and avermectins are used to treat which type of infection

the plasma membrane

Congratulations! You have discovered a new antibiotic. It is lipophilic and detergent-like. On the basis of this information, its target is most likely which of the following

Bacitracin blocks the movement of peptidoglycan subunits from the cytoplasm to the exterior of the cell

How does bacitracin work

Penicillin binds to penicillin-binding proteins, thus inhibiting the transpeptidation reaction during cell wall synthesis.

How does penicillin work

bactericidal agents only

Life-threatening diseases caused by bacterial pathogens should be treated with which of the following

protozoan

Metronidazole and pentamidine are used to treat which type of infection

HIV

Reverse transcriptase inhibitors, such as AZT, can be used to target which virus

dihydrofolic acid synthesis pathway

Sulfa drugs (sulfonamides) inhibit which metabolic pathway

30S ribosomal subunit

The aminoglycosides directly target which structure of the bacterial cell

mostly gram-positive bacteria and some gram-negative bacteria

The penicillins act on which type of bacteria

. target modification

What mechanism of resistance is used by both MRSA and VRSA

A superinfection is a type of secondary infection that can develop when antibiotics kill much of the patient's normal flora

Which describes the difference between a secondary infection and a superinfection

RNA polymerase

Which is the target of the antimicrobial drug known as rifampin

DNA gyrase

Which is the target of the class of antimicrobial drugs known as fluoroquinolones

etravirine

Which of the following antiviral drugs is not a nucleoside analog

Peptide bond formation is inhibited.

Which of the following commonly results from most antibiotic classes that bind to the 50S ribosomal subunit

target modification

Which of the following contributes to the development of antibiotic resistance

ampicillin

Which of the following is a semisynthetic antimicrobial agent

tetracyclin

Which of the following is not a β-lactam antibiotic

chloramphenicol

Which of the following was the first broad-spectrum antibiotic to be approved by the FDA

compound 606

Which was the first antimicrobial agent discovered to treat syphilis

Alexander Fleming

Who is credited for first finding a naturally occurring antimicrobial agent

Paul Ehrlich

Who is credited for first finding an antimicrobial agent?