RPA 4: Immunity and Epidemiology

injection with a toxoid will result in the production of memory T-cells

True

injection with a viral vaccine will result in the production of memory T-cells

True

which of the following vaccine types will initiate infection in a person getting vaccinated?

attenuated

you inject a baby with a virus that has been passaged through tissue culture for multiple generations until it is no longer pathogenic. This is an example of a ____ vaccine

attenuated

Small microbes are more readily neutralized than larger microbes

true

neutralization is the inhibition of toxin binding to cellular receptors due to antibody binding

true

antibody bindings kill microbes

false

both microbes and toxins can be neutralized by antibody

false

only toxins can be neutralized by antibodies

false

During a secondary immune response you will find activated CTL cells in

hours

which cells produce cytokines that stimulate naïve B cells to become active? 1. mature T-helper cells 2. phagocytic cells 3. B-cells 4. CTLs 5. 1 and 2 6. 1, 2 and 3 7. 1, 2, 3 and 4

mature T-helper cells

your neighbor's child has been diagnosed with IgG deficiency. What can they do at normal levels? 1. fix complement 2. phagocytosis 3. neutralize infections and toxins 4. activate CTLs 5. 1 and 2 6. 1, 2 and 3 7. 1, 2, 3, and 4

not 2 only

Your neighbors child has been diagnosed with a IgM deficiency. What can't they do at normal levels?

produce antibodies at the very early stages of an infection, activate B-cells to become plasma cells, respond to infections in the gut, respond to parasite infections

what can people with HIV do at normal levels?

respond to microbes they have had a primary immune response to

Why is PCR superior to ELISA for diagnosis of infection in babies?

ELISAs are not reliable in babies because they have their mom's antibodies

Injection with a gamma globulin shot will result in the production of memory T-cells

False

Injection with an antiserum will result in the production of memory B-cells

False

a toxoid shot induces artificially acquired passive immunity

False

a toxoid shot induces naturally acquired active immunity

False

a viral vaccine induces artificially acquired passive immunity

False

injection with an antitoxin will result in the production of memory B-cells

False

injection with an antitoxin will result in the production of memory T-cells

False

which of the following cells require presentation of antigen by a cell expressing MHCII?

T-helper cells

which of the following provides artificially acquired passive immunity? 1. receiving a toxoid shot 2. receiving an antitoxin shot 3. getting an infection with a virus 4. babies getting antibodies from their mothers through the placenta 5. 1 and 2

2 only

during primary immune response you will find activated CTL cells in

7-10days

without the cells that HIV kills, what other parts of the immune system can't function at normal levels? antibody production CTL killing complement phagocytosis neutralization

ALL

which antibody is found in breast milk?

IgA

which antibody is responsible for the immune response in the intestines?

IgA

which antibody causes allergies when it is made inappropriately?

IgE

You want to know if a baby still has a vaccine neutralizing antibody that it received from its mom in utero. Which of the following types of ELISAs would you run? One that tests for

IgG

You want to know if your mom is having a systemic immune response to a gastroenteritis virus, which causes vomiting. Which of the following types of ELISAs would you run?

IgG

You want to know if your mom is having a systemic immune response to a gastroenteritis virus 2 days after what you think is her first infection. Which of the following types of ELISAs would you run?

IgM

which cells produce cytokines that stimulate naive T-helper cells to become active?

Phagocytic cells