Start Exam 2 WBC Malignancies- Quiz 6

The most common form of leukemia in children is _____. CML AML CLL ALL

ALL

Fatal within weeks if not treated. Cancer cells are of an immature form and unfunctional Acute Leukemia Chronic Leukemia

Acute Leukemia

Which type of leukocyte is created in the bone marrow (myeloid)? Eosinophil Basophil Neutrophil All the above

All the above

In almost all cases of chronic lymphocytic leukemia CLL a fairly mature _____ precursor is at fault. neutrophils B cells NK cell monocytes

B cells

Most cases of _____ are associated with a reciprocal between chromosomes 9 and 22 and resultant formation of a fusion gene. CML AML CLL ALL

CML

Lives much longer without treatment. Cancer cells are in a more mature form and functional. Acute Leukemia Chronic Leukemia

Chronic Leukemia

Acute leukemias have an insidious onset. T/F

F

Reed-Sternberg cells are used to diagnose Non-Hodgkin Lymphoma. T/F

False

Viruses that have been associated with lymphoma include all of the following EXEPT: HIV HPV Epstein-Barr HTLV-1

HPV

Is a type of cancer found in your blood and bone marrow and is caused by the rapid production of abnormal white blood cells. These abnormal white blood cells are not able to fight infection and impair the ability of the bone marrow to produce red blood cells and platelets Leukemia Lymphoma Myeloma Acute Leukemia Chronic Leukemia

Leukemia

Is cancer that often develops within one or more lymph nodes in the lymphatic system. It starts when white blood cells called lymphocytes grow and divide uncontrollably. Leukemia Lymphoma Myeloma Acute Leukemia Chronic Leukemia

Lymphoma

Is a cancer that forms in a type of white blood cell called a plasma cell. Its malignant transformation, forms localized tumors in bony structures. Leukemia Lymphoma Myeloma Acute Leukemia Chronic Leukemia

Myeloma

A myeloid tumor could be derived from a precursor cell in the lineage of any of the following cells types EXCEPT: neutrophils a megakaryocyte NK cell a monocyte

NK cell

Chemotherapy can interfere with the synthesis of DNA causing apoptosis. T/F

True

Myeloma is a tumor originating in _____. any cell type of the myeloid stem cell line a plasma cell an immature T cell an immature B cell

a plasma cell

The difference between leukemia and lymphoma is that leukemia begins in _____ while Lymphoma begins in _____. lymph node, bone marrow spleen, bone marrow bone marrow, spleen bone marrow, lymph node

bone marrow, lymph node

The progression from CML to AML diagnostically complete when a bone marrow aspirate contains more _____ cells. neutrophils blast monocytes B cells T cells

maybe blast

Definitive diagnosis of a white blood cell cancer requires bone marrow or lymph node biopsy. T/F

maybe false, go back to true

Non-Hodgkin lymphoma may effect any of these cell types EXCEPT: neutrophils B cells NK cell T cells

neutrophils

All blood cells originate from: red marrow white marrow

red marrow

Which of the following is NOT known to increase the risk if developing a neoplasm? radiation exposure Klinefelter syndrome sickle cell disease smoking Epstein -Bar virus infection

sickle cell disease

Hodgkin lymphoma spreads in a more predictable manner than Non- Hodgkin lymphoma. T/F

true