5 functions of antibodies

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Antibody mediated cytotoxicity

The Fc region of the antibody interacts with eosinophils which release enzymes and reactive oxygen species to attack parasites

Opsonization

They bind to the surface of immunogens and the Fc region interacts with the phagocytes ("calls" them to the site of infection)

Agglutination

They clump particles together so phagocytosis can occur more efficiently

Neutralization

They stick to antigens and block their attachment sites Stops pathogens from entering the host cells

Complement activation

When antibodies activate a protein that assists in membrane perforation (membrane attack complex)


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