AP Bio 1st Semester Final
A student formulated a hypothesis that water-soluble pollutants damage living organisms by increasing the permeability of cellular membranes. To test the hypothesis, the student investigated the effect of isopropanol and acetone on beet root cells. The vacuoles of beet root cells contain large amounts of betacyanin, a water-soluble pigment that is released into the extracellular environment as a result of increased membrane permeability. The student prepared identical samples of beet root tissue and incubated each sample for 15 minutes in the specific solution for that group. At the end of the incubation period, the student measured the absorbance of 460 nm light for each sample. A greater concentration of betacyanin in the solution surrounding the beet root cells results in a greater absorbance of 460 nm light. The results of the experiment are shown in the table above. Which of the following graphs is the most appropriate representation of the experimental data?
a
In an experiment, the efficiency of oxygen exchange across the plasma membrane is being assessed in four artificial red blood cells. The table above lists some properties of those artificial cells. Other conditions being equal, which artificial cell is predicted to be the most efficient in exchanging oxygen with the environment by diffusion? A The cuboidal cell B The tetrahedral cell C The cylindrical cell D The spherical cell
A
A common laboratory investigation involves putting a solution of starch and glucose into a dialysis bag and suspending the bag in a beaker of water, as shown in the figure below. The investigation is aimed at understanding how molecular size affects movement through a membrane. Which of the following best represents the amount of starch, water, and glucose in the dialysis bag over the course of the investigation?
A
A common test for liver function involves sprinkling sulfur powder onto a sample of urine (mostly water with dissolved bodily waste). Sulfur powder sprinkled on a sample from an individual with impaired liver function will sink because the urine contains a high level of bile salts, while the sulfur powder sprinkled on normal urine samples will float. Which of the following best explains why bile salts cause the sulfur powder to sink? A Bile salts decrease the surface tension of the urine sample. B Bile salts increase the water potential of the urine. C Bile salts increase the density of the urine sample. D Bile salts decrease the strength of the covalent bonds within a water molecule.
A
A small protein is composed of 110 amino acids linked together in a chain. As shown in Figure 1, the first and last five amino acids in the chain are hydrophobic (have nonpolar and uncharged RR-groups), whereas the remaining 100 amino acids are hydrophilic (have charged or polar RR-groups). The nature of the RR-group determines if the amino acid is hydrophobic or hydrophilic. A mutation results in the production of a version of the small protein that is only 105 amino acids long, as shown in Figure 2. Five of the hydrophobic amino acids are missing from one end of the chain. Which of the following best depicts the tertiary structures of the two proteins in water? The diagrams in the options are not drawn to the same scale as those in Figure 1 and Figure 2.
A
A typical bag of fertilizer contains high levels of nitrogen, phosphorus, and potassium but trace amounts of magnesium and calcium. Which of the following best matches the fertilizer component with the molecule in which it will be incorporated by organisms in the area? A Nitrogen will be incorporated into nucleic acids. B Phosphorus will be incorporated into amino acids. C Potassium will be incorporated into lipids. D Magnesium will be incorporated into carbohydrates.
A
If 30% of the nucleotides in a single-stranded RNA molecule are adenine, then what percent are expected to be thymine? A 0% B 20% C 30% D 70%
A
The following questions refer to the following diagram. For each phrase or sentence, select the labeled part to which it is most closely related. Each option may be used once, more than once, or not at all for each group. Site of conversion of chemical energy of glucose to ATP
A
Which of the following best explains why a cell's plasma membrane is composed of two layers of phospholipids rather than just a single layer? A Having two oppositely oriented layers of phospholipids allows only the hydrophilic heads to interact with water inside and outside of the cell. B Having two oppositely oriented layers of phospholipids allows the hydrophilic heads to repel water both inside and outside of the cells. C Having two identically oriented layers of phospholipids gives cells more protection from the exterior environment than just a single layer would. D Having two identically oriented layers of phospholipids allows for the production of vacuoles while still maintaining a protective barrier.
A
Which of the following correctly illustrates a dipeptide and an amino acid in the optimal position to form a tripeptide?
A
Which of the following statements is true regarding the movement of substances across cell membranes? A Ions are unable to move through the phospholipid bilayer because the nonpolar tail regions of the phospholipids are hydrophobic. B Ions are able to move through the phospholipid bilayer because the polar head regions of the phospholipids are charged. C Water is able to move through the phospholipid bilayer because the nonpolar tail regions of the phospholipids are charged. D Water is unable to move through the phospholipid bilayer because the polar head regions of the phospholipids are charged.
A
A culture of Spirogyra (an autotrophic alga) is maintained in a water solution containing dissolved carbon dioxide and a source of phosphates but lacking nitrogen compounds. A researcher determines the rates of synthesis of several organic compounds found in the Spirogyra before and after several weeks in the water solution. Which of the following graphs best illustrates a likely result of the experiment?
B
A mutation in the gene coding for a single-polypeptide enzyme results in the substitution of the amino acid serine, which has a polar R group, by the amino acid phenylalanine, which has a nonpolar R group. When researchers test the catalysis of the normal enzyme and the mutated enzyme, they find that the mutated enzyme has much lower activity than the normal enzyme does. Which of the following most likely explains how the amino acid substitution has resulted in decreased catalytic activity by the mutated enzyme? A The substitution decreased the mass of the enzyme so that the mutated enzyme binds more weakly to the substrate than the normal enzyme does. B The substitution altered the secondary and tertiary structure of the enzyme so that the mutated enzyme folds into a different shape than the normal enzyme does. C The substitution caused many copies of the mutated enzyme to cluster together and compete for substrate to bind. D The substitution caused the directionality of the enzyme to change such that the amino terminus of the normal enzyme has become the carboxy terminus of the mutated enzyme.
B
A researcher measured the temperature at which two different samples of double-stranded DNADNA denature (separate into single strands). Sample 11 denatured at a significantly lower temperature than sample 22 did. Based on the data, the researcher claims that the DNADNA in sample 22 is composed of a higher percentage of guanine and cytosine than the DNADNA in sample 11 is. Which of the following best supports the researcher's claim? A The bonds between guanine and cytosine are covalent bonds, which require more energy to disrupt than those between adenine and thymine. B Guanine-cytosine pairs denature at a higher temperature because they have more hydrogen bonds between them than adenine-thymine pairs do. C Adenine-thymine pairs require less energy to separate because adenine and thymine are both single-ring bases. D Guanine-cytosine pairs require more energy to separate because one is a purine and one is a pyrimidine.
B
A student formulated a hypothesis that water-soluble pollutants damage living organisms by increasing the permeability of cellular membranes. To test the hypothesis, the student investigated the effect of isopropanol and acetone on beet root cells. The vacuoles of beet root cells contain large amounts of betacyanin, a water-soluble pigment that is released into the extracellular environment as a result of increased membrane permeability. The student prepared identical samples of beet root tissue and incubated each sample for 15 minutes in the specific solution for that group. At the end of the incubation period, the student measured the absorbance of 460 nm light for each sample. A greater concentration of betacyanin in the solution surrounding the beet root cells results in a greater absorbance of 460 nm light. The results of the experiment are shown in the table above. Based on the data from the investigation, which of the following is the best scientific question about organisms living in water that is polluted with organic solvents? A Do organisms without pigments have a selective advantage in polluted environments? B Will organisms living in polluted environments exhibit detrimental effects from an increased permeability of their cellular membranes? C Will organic solvents from the environment become incorporated into the cell membranes of organisms living in polluted environments? D Should governments place more stringent restrictions on the release of organic solvents into aquatic ecosystems?
B
Amylase is an enzyme that converts carbohydrate polymers into monomers. Glycogen synthase is one of the enzymes involved in converting carbohydrate monomers into polymers. Which of the following best explains the reactions of these enzymes? A Amylase aids in the removal of a water molecule to break covalent bonds whereas glycogen synthase aids in the addition of a water molecule to form covalent bonds. B Amylase aids in the addition of a water molecule to break covalent bonds whereas glycogen synthase aids in the removal of a water molecule to form covalent bonds. C Amylase aids in the addition of a water molecule to form covalent bonds whereas glycogen synthase aids in the removal of a water molecule to break covalent bonds. D Amylase aids in the removal of a water molecule to form covalent bonds whereas glycogen synthase aids in the addition of a water molecule to break covalent bonds.
B
DNA and RNA are nucleic acids that can store biological information based on the sequence of their nucleotide monomers. Figure 1 shows a short segment of each of the two types of nucleic acids (NA #1 is single strand and NA#2 is double stranded) Which of the following best describes a structural difference between DNA and RNA? A DNA contains four types of nitrogenous bases, whereas RNA contains only two types of nitrogenous bases. B The backbone of DNA contains deoxyribose, whereas the backbone of RNA contains ribose. C A DNA molecule is composed of two parallel strands with the same 5′5′ to 3′3′ directionality, whereas an RNA molecule is composed of only one 5′5′ to 3′3′ strand. D Phosphate groups provide rigidity to DNA, but RNA is flexible and contains no phosphate groups.
B
Figure 1 represents a nucleic acid fragment that is made up of four nucleotides linked together in a chain. Figure 1. Nucleic acid fragment Which of the following characteristics of Figure 1 best shows that the fragment is RNARNA and not DNADNA? A The 5′5′ to 3′3′ orientation of the nucleotide chain B The identity of each nitrogenous base C The charges on the phosphate groups D The type of bond linking the nucleotides together
B
Humans produce sweat as a cooling mechanism to maintain a stable internal temperature. Which of the following best explains how the properties of water contribute to this physiological process? A The high specific heat capacity of water allows the body to absorb a large amount of excess heat energy. B The high heat of vaporization of water allows the body to remove excess heat through a phase change of water from liquid to gas. C The high surface tension of water contributes to the physical process by which water leaves the body. D The high melting temperature of water allows the body to remove excess heat through a phase change of water from solid to liquid.
B
Liver cells manufacture glycoproteins, while adipose cells store fat. Which of the following subcellular structures is likely to be more prominent in liver cells than in adipose cells? A Nucleus B Golgi apparatus C Cytoskeleton D Plasma membrane
B
Paramecia are unicellular protists that have contractile vacuoles to remove excess intracellular water. In an experimental investigation, paramecia were placed in salt solutions of increasing osmolarity. The rate at which the contractile vacuole contracted to pump out excess water was determined and plotted against osmolarity of the solutions, as shown in the graph. Which of the following is the correct explanation for the data? A At higher osmolarity, lower rates of contraction are required because more salt diffuses into the paramecia. B The contraction rate increases as the osmolarity decreases because the amount of water entering the paramecia by osmosis increases. C The contractile vacuole is less efficient in solutions of high osmolarity because of the reduced amount of ATP produced from cellular respiration. D In an isosmotic salt solution, there is no diffusion of water into or out of the paramecia, so the contraction rate is zero.
B
Researchers compared similar proteins from related organisms in different habitats. They found that the proteins from organisms living in harsh environments had a greater number of cysteine amino acids than did proteins from organisms not living in harsh environments. The structure of cysteine is shown. Bonds can form between the sulfur atom of different cysteine amino acids (S-SS-S bonds). Figure 1. Chemical structure of cysteine Which of the following best describes the effect of a greater number of cysteine amino acids on the stability of the proteins? A The change has no effect on the stability of the protein because only one type of amino acid is involved. B The change leads to increased protein stability because of an increased number of S-SS-S bonds in the tertiary structure of the proteins. C The change leads to decreased protein stability because of an increased number of S-SS-S bonds in the tertiary structure of the proteins. D The change leads to increased protein stability only when the added cysteine amino acids are next to other cysteine amino acids in the primary structure.
B
Ultraviolet (UVUV) radiation can damage DNADNA by breaking weak bonds. Which of the following best explains how this occurs? A UVUV radiation disrupts the double helix structure by breaking the covalent bonds between the nitrogenous base pairs. B UVUV radiation disrupts the double helix structure by breaking the hydrogen bonds between the nitrogenous base pairs. C UVUV radiation is able to break DNADNA strands in two by breaking covalent bonds between the sugar-phosphate backbone molecules. D UVUV radiation is able to break DNADNA strands in two by breaking hydrogen bonds between the sugar-phosphate backbone molecules.
B
Water and ammonia interact to form hydrogen bonds, as represented in the figure. Which statement best helps explain the formation of the hydrogen bond represented in the figure? A The oxygen has a partial positive charge, and the nitrogen has a partial negative charge. B The nitrogen has a partial negative charge, and the hydrogen attached to the oxygen has a partial positive charge. C The hydrogen attached to the oxygen has a partial negative charge, and the nitrogen also has a partial negative charge. D The nitrogen has a partial positive charge, and the hydrogen attached to the oxygen also has a partial positive charge.
B
Which of the following best describes how amino acids affect the tertiary structure of a protein? A The number of amino acids determines the tertiary structure of the protein. B The interactions of the different RR-groups with other RR-groups and with their environment determine the tertiary structure of the protein. C The RR-group of the last amino acid that is added to a growing polypeptide chain determines the next amino acid that is added to the chain. D The sequence of the amino acids in the polypeptide chain determines the protein's primary structure but has no effect on its tertiary structure.
B
Which of the following best describes the structures of carbohydrates? A They only occur as disaccharides. B They occur as monomers, chains of monomers, and branched structures. C They only occur as long and branched structures. D They occur as chains of monomers that hydrogen bond with complementary chains of monomers.
B
Which of the following statements best describes how organisms such as rabbits obtain the carbon necessary for building biological molecules? A Rabbits eat plants and use energy absorbed from the plants to make carbon atoms from electrons, protons, and neutrons in the air. B Rabbits eat plants and break down plant molecules to obtain carbon and other atoms that they rearrange into new carbon-containing molecules. C Rabbits eat plants and use water absorbed from the plants to hydrolyze CO2CO2, which the rabbits breathe in from the air and use as a carbon source. D Rabbits eat plants and make carbon-containing molecules by using carbon atoms that the plants absorbed from the soil and stored in the cells of their leaves.
B
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B
Intravenous (IV) solutions administered to patients are normally isotonic. Which of the following is most likely if an IV of distilled water is administered to a patient? A The cells that are exposed to hypotonic solutions will shrink as a result of salt moving into the blood. B The liver will secrete additional bile salts into the blood to raise the tonicity of the administered fluid. C The cells that are exposed to hypotonic solutions will expand as water moves osmotically into the cells from the blood. D The patient's respiration rate will slow to compensate for the higher levels of circulating blood.
C
Students conducted a controlled experiment to investigate whether sawdust provides enough nutrients to support plant growth. The students separated ten nearly identical sunflower seedlings into two groups. They grew the seedlings in the first group in potting soil and the seedlings in the second group in sawdust composed mostly of cellulose. After twenty days, the students recorded observations about the seedlings in each group. The students' observations are presented in the table. Treatment GroupMean Seedling HeightObservationsSeedlings in potting soil18.5 cm18.5 cmThe leaves have a dark green color and are normal in size.Seedlings in sawdust4.8 cm4.8 cmThe leaves have a grayish color and are small in size. The observed differences between the groups most likely resulted from differences in the ability of the seedlings to produce which of the following monomers? A - carbohydates B- amino acid C- amino acid and nucleic acid D- nucleic acid and lipids
C
The amino acid in Figure 1 is found in a region of a polypeptide that folds away from water. Which part of the amino acid most likely contributes to the hydrophobic behavior of this region of the polypeptide? A Amine (NH2NH2) group B Carboxyl (COOHCOOH) group C Methyl (CH3CH3) group D Hydrogen (HH) atom
C
The carbohydrates glucose, galactose, and fructose have the same chemical formula (C6H12O6)(C6H12O6) but different structural formulas, as represented in the figure. Which of the following statements about glucose, galactose, and fructose is most likely true? A The carbohydrates have the same properties because they have the same number of carbon, hydrogen, and oxygen atoms. B The carbohydrates have the same properties because they each have a single carbon-oxygen double bond. C The carbohydrates have different properties because they have different arrangements of carbon, hydrogen, and oxygen atoms. D The carbohydrates have different properties because they have different numbers of carbon-carbon bonds.
C
The figure above shows a series of microscope images taken over time of ovalbumin production in chick oviduct cells in response to stimulation with estrogen. The ovalbumin protein was detected using a fluorescent dye as shown by the white areas in the time-lapse sequence. The microscope images indicate that ovalbumin A is synthesized on soluble ribosomes and packaged into lysosomes, from which it is secreted into the oviduct B is synthesized on ribosomes bound to the rough endoplasmic reticulum, and then secreted directly into the oviduct C crosses the endoplasmic reticulum membrane as it is translated, then moves to the Golgi apparatus, then to vesicles from which it is secreted D crosses the Golgi apparatus membrane post-translationally, is taken up by the Golgi apparatus and endoplasmic reticulum, then is packaged into secretory vesicles
C
The molecular structures of linoleic acid and palmitic acid, two naturally occurring substances, are shown in the figure. Based on the molecular structures shown in the figure, which molecule is likely to be solid at room temperature? A Linoleic acid, because the absence of carbon-carbon double bonds allows the molecules to pack closely together. B Linoleic acid, because the presence of carbon-carbon double bonds prevents the molecules from packing closely together. C Palmitic acid, because the absence of carbon-carbon double bonds allows the molecules to pack closely together. D Palmitic acid, because the presence of carbon-carbon double bonds prevents the molecules from packing closely together.
C
The sequences for two short fragments of DNA are shown above. Which of the following is one way in which these two segments would differ? A Segment 1 would not code for mRNA because both strands have T, a base not found in RNA. B Segment 1 would be more soluble in water than segment 2 because it has more phosphate groups. C Segment 1 would become denatured at a lower temperature than would segment 2 because A-T base pairs have two hydrogen bonds whereas G-C base pairs have three. D Segment 1 must be from a prokaryote because it has predominantly A-T base pairs.
C
Which of the following best describes the hydrolysis of carbohydrates? A The removal of a water molecule breaks a covalent bond between sugar monomers. B The removal of a water molecule forms a covalent bond between sugar monomers. C The addition of a water molecule breaks a covalent bond between sugar monomers. D The addition of a water molecule forms a covalent bond between sugar monomers.
C
Which of the following best describes the process by which gas from the atmosphere is obtained by plants and used to build lipids? A Gas is fixed by plants as part of the sulfur cycle. B Gas is fixed by plants as part of the nitrogen cycle. C Gas is directly obtained by plants as part of the carbon cycle. D Gas is directly obtained by plants as part of the magnesium cycle.
C
A cell is treated with a drug that prevents the formation of new lysosomes. The cell continues to transcribe the genes that code for the hydrolytic enzymes that are normally found in lysosomes and continues to translate the mRNAs for those proteins on membrane-bound ribosomes. The hydrolytic enzymes are most likely to accumulate in which of the following cellular structures? A Nucleus B Mitochondrion C Smooth endoplasmic reticulum D Golgi complex
D
Figure 1 is a diagram of water molecules at the air-water interface at the surface of a pond. Figure 1. Alignment of water molecules at air-water interface Based on Figure 1, which of the following best describes how the properties of water at an air-water interface enable an insect to walk on the water's surface? A Covalent bonds between water molecules and the air above provide cohesion, which causes tiny bubbles to form under the feet of the insect. B Ionic bonds between molecules at the surface of the water provide an electric charge, which attracts the feet of the insect, keeping it on the surface. C Polar covalent bonds between molecules at the surface of the water provide adhesion, which supports the weight of the insect. D Hydrogen bonds between molecules at the surface of the water provide surface tension, which allows the water surface to deform but not break under the insect.
D
Figure 1 represents a common process that occurs in organisms. Figure 1. Structural formula for a common biological reaction (Two molecules being added together that both contain CHON to form one molecule and a water molecule) Which of the following is an accurate description of the process shown in Figure 1 ? A The linking of amino acids with an ionic bond as an initial step in the protein synthesis process B The formation of a more complex carbohydrate with the covalent bonding of two simple sugars C The hydrolysis of amino acids with the breaking of covalent bonds with the release of water D The formation of a covalent peptide bond in a dehydration synthesis reaction
D
Polypeptides are continuously being formed and degraded. One of these processes is shown. (Figure shows the adding of a water to a molecule and the molecules breaking into two.) Figure 1. Polypeptide reaction Which statement is the most accurate description of the reaction shown in Figure 1? A It represents monomers linked by dehydration synthesis. B It represents a polypeptide chain that folds to form the tertiary structure. C It represents a polypeptide chain that is denatured into the primary structure. D It represents a polypeptide chain that is broken down through a hydrolysis reaction.
D
The CFTRCFTR protein is made up of 1,4801,480 amino acids linked together in a chain. Some humans produce a version of the CFTRCFTR protein in which phenylalanine (an amino acid) has been deleted from position 508 of the amino acid chain. Which of the following best predicts how the amino acid deletion will affect the structure of the CFTRCFTR protein? A It will have no observable effect on the structure of the CFTR protein. B It will affect the primary structure of the CFTR protein, but the other levels of protein structure will not be affected. C It will affect the secondary and tertiary structures of the CFTR protein, but the primary structure will not be affected. D It will affect the primary, secondary, and tertiary structures of the CFTR protein.
D
The manner in which several different ions and molecules move through a cell membrane is shown in the diagram above. For each ion or molecule, the relative concentration on each side of the membrane is indicated. Which of the following accurately describes one of the movements taking place? A Glucose is transported into the cell by active transport. B Na+ is transported into the cell by active transport. C The movement of glucose through the membrane requires ATP hydrolysis. D
D
Which of the following conclusions is most clearly supported by the representations of nucleic acid #1#1 and nucleic acid #2#2 ? A Nucleic acid #1#1 contains only purines, whereas nucleic acid #2#2 contains only pyrimidines. B Nucleic acid #1#1 contains the sugar ribose, whereas nucleic acid #2#2 contains the sugar deoxyribose. C Nucleic acid #1#1 contains positively charged phosphate groups, whereas nucleic acid #2#2 does not. D Nucleic acid #1#1 contains adenine-thymine base pairs, whereas nucleic acid #2#2 does not.
D
Contains hydrolytic enzymes associated with the intracellular digestion of macromolecules A Centriole B Lysosome C Nucleolus D Peroxisome
b
The following questions refer to the following diagram. For each phrase or sentence, select the labeled part to which it is most closely related. Each option may be used once, more than once, or not at all for each group. Evolved from a photoautotrophic prokaryote A A B B C C D D E E
b
A sample of human blood was placed in a test tube containing a physiological saline solution (0.9% sodium chloride). This type of solution is often used intravenously to quickly rehydrate patients. A drop of the blood from the test tube was placed on a slide and red blood cells (RBCs) were observed under a microscope. Three possible outcomes are diagrammed below. Which of the following best predicts which diagrammed microscope view the laboratory worker would see and best explains why? A View 1 because RBC membranes are freely permeable to water B View 2 because the RBCs use energy to allow sodium entry and to pump water out C View 2 because the rate of water movement into the RBCs equals the rate of water movement out of the cells D View 3 because the sodium-potassium pumps in the RBC membranes use energy to keep the sodium out but allow water to freely flow into the cells
c
Bacteriophages are viruses that infect bacteria. In an experiment, bacteriophages were labeled with either radioactive phosphorus or radioactive sulfur. The labeled bacteriophages were incubated with bacteria for a brief amount of time and then removed. The infected bacteria cells were found to contain significant amounts of radioactive phosphorus but not radioactive sulfur. Based on the results of the experiment, which of the following types of molecules did the bacteriophages most likely inject into the bacteria cells? A Simple carbohydrate B Amino acid C DNA D Polypeptide
c
Membrane-bound organelles have been an important component in the evolution of complex, multicellular organisms. Which of the following best summarizes an advantage of eukaryotic cells having internal membranes? A Eukaryotic cells are able to reproduce faster because of the presence of organelles. B Some organelles, such as mitochondria and chloroplasts, are similar to prokaryotic cells in structure. C Organelles isolate specific reactions, increasing metabolic efficiency. D Compartmentalization leads to a higher mutation rate in DNA, which leads to more new species.
c
The figure above represents a rough endoplasmic reticulum. Which of the following best describes the role of the structure labeled Y? A Structure Y contributes the raw materials required for the synthesis of proteins. B Structure Y packages proteins for export from the cell. C Structure Y is the location where proteins are synthesized. D Structure Y contains enzymes that cut and activate proteins.
c
Which of the following best describes the formation of the bond shown in Figure 1 ? A An ionic bond is formed between a carbon atom of one amino acid and the nitrogen atom of the other amino acid. B An ionic bond is formed when the negative charge of an OHOH group is balanced by the positive charge of a hydrogen ion. C A covalent bond is formed between a carbon atom and a nitrogen atom along with the formation of H2OH2O . D A covalent bond is formed that replaces the hydrogen bond between the OHOH group and the HH atom.
c
