Basic Tissues 2

Which of the following statements about elastic fibers is correct? A. They can stretch 150% of their length B. They are composed of fibrillin and elastin. C. Abnormal fibrillin genes cause Marfan syndrome. D. Only B and C. E. A, B, and C.

E. A, B, and C.

Your patient has overcome a gingival infection. Which statement is CORRECT? A. During inflammation, monocytes migrated into the area to become phagocytic cells. B. Tissue fluid decreased during the inflammatory stage of recovery. C. Pericytes migrated into the gingiva to become neutrophils. D. Only A and B. E. A, B, and C.

A. During inflammation, monocytes migrated into the area to become phagocytic cells

Select the INCORRECT statement concerning the macrophage? A. Macrophage phagocytosis is decreased after opsonization. B. Kupffer cells are specialized macrophages located in the liver. C. A macrophage can be a fixed or a wandering connective tissue cell. D. Multinuclear giant cells are one type of macrophage. E. One of the functions of the macrophage is antigen presentation.

A. Macrophage phagocytosis is decreased after opsonization.

Select the INCORRECT statement concerning mast cells. A. Mast cells release Thromboxane A2 to dilate blood vessels. B. Mast cells release Eosinophil Chemotactic Factor to attract eosinophils to the site of inflammation to destroy parasites. C. Mast cells in areolar connective tissue have IgE on their surface. D. Mast cells release Neutrophil Chemotactic Factor to kill microorganisms. E. Mast cells are filled with metachromatic secretory granules.

A. Mast cells release Thromboxane A2 to dilate blood vessels.

The diseases listed below are all inherited disorders of connective tissue EXCEPT: A. Scleroderma B. Ehlers-Danlos syndrome (EDS) C. Epidermolysis bullosa D. Osteogenesis imperfecta E. Marfan syndrome

A. Scleroderma

All of the following statements correctly describe plasma cells EXCEPT: A. They are "wandering" connective tissue cells. B. They are ovoid, eosinophilic with juxtanuclear Golgi, and a small amount of endoplasmic reticulum. C. They secrete antibodies. D. The classic hallmark of the plasma cell is a "clock face" pattern of nuclear chromatin with the prominent nucleolus in the center surrounded by clumps of heterochromatin. E. They arise from B-lymphocytes.

B. They are ovoid, eosinophilic with juxtanuclear Golgi, and a small amount of endoplasmic reticulum.

All of the following are cells with functions that are required in wound healing EXCEPT: A. Pericytes which are multipotential and give rise to connective tissue and blood vessels. B. Fibroblasts which synthesize new extracellular matrices. C. Adipocytes which serve as an energy supply. D. Mast cells which recruit phagocytes to kill microorganisms, if present. E. A and B (Neither pericytes nor fibroblasts are necessary for wound healing.)

C. Adipocytes which serve as an energy supply.

Which description of mesenchymal connective tissue is FALSE? A. It contains mesenchymal cells which give rise to most of the cells of loose connective tissue. B. It has a gel-like, amorphous ground substance. C. It is mainly present in the adult. D. Only A and B. E. A, B, and C.

C. It is mainly present in the adult.

Which cell type is pluripotent and lacks cellular organelles? A. fibroblast B. mast cell C. mesenchymal cell D. plasma cell E. multilocular adipose cell

C. mesenchymal cell

Which of the following statements regarding dense irregular collagenous connective tissue is FALSE? A. The tissue has limited ground substance. B. This tissue constitutes the deeper dermis of skin. C. The sheaths of nerves and the capsules of joints are mainly dense irregular collagenous connective tissue. D. Abundant reticular fibers are present. E. The tissue has tightly packed collagen fibers interwoven into a meshwork resistant to stress from all directions.

D. Abundant reticular fibers are present.

Which of the following description of connective tissue fibers is correct? A. Each collagen fiber bundle is composed of smaller fibrils, which in turn consist of aggregates of tropocollagen molecules. B. Reticular fibers are produced by reticular cells, which are a type of fibroblast that synthesizes type III collagen. They form a mesh-like network that stains with silver. C. Reticular fibers are composed of type III collagen which is thicker and contains less carbohydrate than type I collagen fibers. D. Only A and B. E. A, B, and C.

D. Only A and B.

You can find connective tissues that have little or no matrix and few fibers in each of the following sites EXCEPT the: A. white fat B. brown fat C. dental pulp D. aorta

D. aorta

You would expect to find dense regular elastic connective tissue in: A. the tendon of a shoulder joint. B. connective tissue under the mucosa of the esophagus. C. the dermis of skin. D. large blood vessels. E. the periodontal ligament.

D. large blood vessels.

Find the CORRECT description of ground substance. A. Ground substance has three classes of compounds: glycosaminoglycans, proteoglycans, and multiadhesive glycoproteins. B. Ground substance is a complex of macromolecules that fills the space between fibers and cells. C. Hyaluronic acid is the most ubiquitous glycosaminoglycan. D. Multiadhesive glycoproteins have attached carbohydrates. They adhere cells to the surrounding substrate. E. All of above are correct.

E. All of above are correct.

Select the INCORRECT statement concerning connective tissue. A. Mesenchymal cells from mesoderm give rise to connective tissues and their cells. B. The functions of connective tissue include space filling, cushioning, protecting, and participating in immune responses. C. Some connective tissues can function as an endocrine organ to regulate body metabolism. D. Glycosaminoglycans (GAGs), proteoglycans, and adhesive proteins are found in the extracellular matrix of connective tissue. E. The main components (composition) of connective tissue are fibroblasts and ground substance.

E. The main components (composition) of connective tissue are fibroblasts and ground substance.

During tissue repair, which cell functions in producing collagen and ground substances? A. plasma cell B. macrophage C. fibrocyte D. mast cell E. fibroblast

E. fibroblast