Bio 133

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Mendelian Traits

determined by a single gene in which sometimes some genes are multifunctional (not controlled by a single gene

DNA

Deoxyribonucleic acid is a molecule that carries most of the genetic instructions used in the development, functioning and reproduction of all known living organisms and many viruses.

William Bateson

English biologist ,and first person to use the term genetic to describe the study of heredity

rRNA

In molecular biology, ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.

RNA

Ribonucleic acid (RNA) is a polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes.

Gene pool

The gene pool is the set of all genes, or genetic information, in any population, usually of a particular species.

tRNA

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation, which is a process that synthesizes a protein from an mRNA molecule.

Alleles

Variants of genes form by mutation

Mutation

a mutation is a permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

Genomic Medicine

an emerging medical discipline that involves using genomic information about an individual as part of their clinical care (e.g., for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use."

Transfer RNA

is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length, that serves as the physical link between the mRNA and the amino acid sequence of proteins.

Evolution

s change in the heritable traits of biological populations over successive generations.[1]

Karyotype

s the number and appearance of chromosomes in the nucleus of an eukaryotic cell. The term is also used for the complete set of chromosomes in a species, or an individual organism.

Nucleotides

structural components or building blocks of Dna

Phenotypes

the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, phenology, behavior, and products of behavior (such as a bird's nest).

Chromosomes .....

there are 46 Chromosomes /cell in which each chromosome included hundreds of different genes

Gene

A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity.

Genome

A genome is an organism's complete set of DNA, including all of its genes. Each genome contains all of the information needed to build and maintain that organism.

Germline mutations

A germline mutation is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring, while, on the other hand, those in somatic cells are not.

Sequences of Nucleotides

A(Adenine) ,T(Thymine),G(Guanine ),C(Cytosine)

Autosomes

An autosome is a chromosome that is not an allosome (a sex chromosome).[1] Autosomes appear in pairs whose members have the same form but differ from other pairs in a diploid cell, whereas members of an allosome pair may differ from one another and thereby determine sex. The DNA in autosomes is collectively known as atDNA or auDNA.[2]

Gregor John Mendel

Austrian Monk who discovered the basic principles of heredity through experiments in his garden

Chromosome

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from parents to offspring, DNA contains the specific instructions that make each type of living creature unique.

genetic determinism

Genetic determinism is the mechanism by which genes, along with environmental conditions, determine morphological and behavioral phenotypes.

Hemoglobin gene

Hemoglobin is the protein molecule in red blood cells that carries oxygen from the lungs to the body's tissues and returns carbon dioxide from the tissues back to the lungs. Hemoglobin is made up of four protein molecules (globulin chains) that are connected together.

Genotypes

Homozygous ,heterozygous ,and hemizygous

Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

mRNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

Somatic Mutations

Somatic mutation, genetic alteration acquired by a cell that can be passed to the progeny of the mutated cell in the course of cell division. Somatic mutations differ from germ line mutations, which are inherited genetic alterations that occur in the germ cells (i.e., sperm and eggs).

Exome

The exome is the part of the genome formed by exons, the sequences which when transcribed remain within the mature RNA after introns are removed by RNA splicing.

Genotype

he genotype is that part (DNA sequence) of the genetic makeup of a cell, and therefore of an organism or individual, which determines a specific characteristic (phenotype) of that cell/organism/individual.


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