Ch 19-3 Blood: Red Blood Cells

How many Hemoglobin molecules do Red Blood Cell contain?

280 million Hb molecules

Damaged RBCs are continuously replaced at a rate of approximately?

3 million new RBCs entering the bloodstream per second. They are replaced before they Hemolyze (rupture).

Molecules of Hemoglobin account for more than ___% of the proteins in RBCs.

95% of the proteins in RBCs.

Hemoglobin

A protein composed of four globular subunits, each bound to a heme molecule; gives red blood cells the ability to transport oxygen in the blood.

What is Anemia?

Anemia interferes with oxygen delivery to peripheral tissues.

What makes up 95% of the proteins in Red Blood Cells?

Hemoglobin accounts for more than 95% of its intracellular proteins.

Hemoglobin consists of four globular proteins subunit. Each subunit contains a single molecule of heme, What is Heme?

The deep red, non-protein, iron-containing component of hemoglobin that carries oxygen.

Sickle Cell Anemia results from?

a mutation affecting the amino acid sequence of the beta chains of the Hemoglobin molecule.

Where are Red Blood Cells produced?

in the Red Bone Marrow

Define Erythropoiesis

the formation of red blood cells, occurs only in red bone marrow (myeloid tissue).