CH. 33 - Eukaryotic Pathogens: Fungi & Protozoa

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Azole medications inhibit the production of ergosterols. Against which infection would they be most effective?

a ringworm infection of the scalp

Leishmania is a protozoal parasite are transmitted by the bite of infected female sandflies. They are then phagocytized and live within host leukocytes. Which type of cell is most likely to harbor them?

macrophages

Eukaryotic human parasites are all respiratory aerobes.

False

A group of college students went backpacking in the mountains. They boiled water from wilderness streams for 15 minutes for all of their cooking and drinking. A few days after returning, they all came down with explosive, foul-smelling, watery diarrhea along with intestinal cramps, nausea, and malaise. Which parasite would you suspect?

Giardia intestinalis (G. lamblia)

Amphotericin B is an antifungal medication. What might its mechanism of action be?

It binds to ergosterol.

Entamoeba histolytica, transmitted by contaminated food, grows on and in the cells lining the intestine and later within the intestinal wall. This results in dysentery. What best describes the relationship between E. histolytica and its host?

It is a parasitic relationship.


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