Chapter 11

Cell suicide

Apoptosis

Lysis of the cell

Apoptosis involves all but the following

Ligand gates ion channel

Binding of a signaling molecule to which type of receptor leads directly to a change in the distribution of ions on opposite sides of the membrane

cAMP

Consider this pathway: epinephrine to G protein coupled receptor to G protein to adenylyl Cyclase to cAMP. Identify the second messenger

Intercellular receptors are present only in target cells

Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because

They amplify the original signal manyfold

Phosphorylation cascades involving a series of protein synthesis kinases are useful for cellular signal transduction because

Activation of G-protein-coupled receptors

Protein phosphorylation is commonly involved with all of the following except

Dimerization and phosphorylation

The activation of receptor tyrosine kinases is characterized by

Amplifies a signal

What does a phosphorylation cascade do

Glycogen breakdown was observed only when epinephrine was administered to intact cells

Which observation suggested to Sutherland the involvement of a second messenger in epinephrines effect on liver cells