Chapter 17-Blood
11) An individual who is blood type AB negative ________. A) can receive any blood type in moderate amounts except that with the Rh antigen B) can donate to all blood types in moderate amounts C) can receive types A, B, and AB, but not type O D) can donate to types A, B, and AB, but not to type O
A
13) Contains a U- or an S-shaped nucleus; granules stain very dark; releases histamine and heparin. A) Basophil B) Eosinophil C) Monocyte D) Erythrocyte E) Neutrophil
A
16) Thrombin catalyzes the activation of these molecules present in plasma. A) Fibrinogen B) Albumin
A
17) Forms the structural framework of a blood clot. A) Fibrinogen B) Albumin
A
19) No visible cytoplasmic granules are present in ________. A) monocytes B) basophils C) eosinophils D) neutrophils
A
19) Transport proteins that bind to lipids and fat-soluble vitamins. A) Beta globulins B) Embolus C) Anemia D) Clotting
A
21) Which of the following are not currently known red blood cell antigens? A) Carson B) Lewis C) Kell D) Duffy
A
24) The slowest step in the clotting process is ________. A) formation of prothrombin activator B) production of fibrin strands C) binding fibrin strands D) release of PF3
A
25) Protein capable of changing shape and color in the presence of O2. A) Hemoglobin B) Agglutination C) Monocyte D) Factor VIII E) Neutrophil
A
27) Which of the following is characteristic of all leukocytes? A) They are nucleated. B) They have cytoplasmic granules. C) They are phagocytic. D) They are the most numerous of the formed elements in blood
A
29) Platelets ________. A) stick to the damaged area of a blood vessel and help seal the break B) have a life span of about 120 days C) are the precursors of leukocytes D) have multiple nuclei
A
30) Select the correct statement regarding age-related blood disorders. A) They include anemias and thromboembolic disorders. B) They are usually the result of the red blood cells wearing out. C) Increased incidence of leukemia is not usually associated with aging. D) They are caused by abnormal forms of hemoglobin F.
A
31) A fibrous protein that gives shape to an RBC plasma membrane. A) Spectrin B) Plasma C) Thrombus D) Whole blood E) Water
A
31) Which sequence is correct for the following events? 1. fibrinogen → fibrin 2. clot retraction 3. formation of thromboplastin 4. prothrombin → thrombin A) 3, 4, 1, 2 B) 1, 2, 3, 4 C) 4, 3, 1, 2 D) 3, 2, 1, 4
A
32) Fredʹs blood was determined to be AB positive. What does this mean? A) There are no antibodies to A, to B, or to Rh antigens in the plasma. B) Antibodies to A and B are present in the red cells. C) His blood lacks Rh factor. D) He can only receive blood from a donor who is AB positive.
A
35) A hormone-stimulating erythropoiesis. A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
A
35) All of the following conditions impair coagulation except ________. A) vascular spasm B) vitamin K deficiency C) severe hypocalcemia D) liver disease
A
37) Complications of aplastic anemia generally do not include ________. A) increase of leukocytes as a result of erythrocyte loss B) suppressed immunity C) impaired formation of all formed elements D) bleeding disorders
A
39) What organ in the body regulates erythrocyte production? A) Kidney B) Brain C) Liver D) Pancreas
A
4) Together, leukocytes and platelets comprise approximately ________ percent of total blood volume. A) 1 B) 75 C) 45 D) 10
A
7) Which of the following is a protective function of blood? A) prevention of blood loss B) maintenance of adequate fluid volume C) maintenance of normal pH in body tissue D) maintenance of body temperature
A
9) Which of the following might trigger erythropoiesis? A) hypoxia of EPO-producing cells B) decreased tissue demand for oxygen C) an increased number of RBCs D) moving to a lower altitude
A
Using Figure 17.1, match the following: 4) Neutrophil.
A
Using Figure 17.1, match the following: 5) Most common white blood cell found in whole blood.
A
Using Figure 17.1, match the following: 9) Main bacteria killer during acute infections.
A
1) ________ is a pivotal molecule associated with the external surfaces of aggregated platelets and is involved in the intrinsic and extrinsic mechanisms of blood clotting. A) PGI2 B) PF3 C) Thrombin D) Thromboplastin (prothrombin activator)
B
10) As red blood cells age ________. A) ATP production increases B) membranes ʺwear outʺ and the cells become damaged C) they will eventually be excreted by the digestive system D) iron will be excreted by the kidneys
B
10) Nucleus has two lobes; contains granules of lysosomal enzymes; functions in attacking parasitic worms. A) Basophil B) Eosinophil C) Monocyte D) Erythrocyte E) Neutrophil
B
15) The major contributor to plasma osmotic pressure. A) Fibrinogen B) Albumin
B
18) All of the following can be expected with polycythemia except ________. A) high hematocrit B) low blood viscosity C) increased blood volume D) high blood pressure
B
18) Makes up most of plasma protein. A) Fibrinogen B) Albumin
B
20) Floating intravascular clot. A) Beta globulins B) Embolus C) Anemia D) Clotting
B
20) Which of the following is not a phase of hemostasis? A) vascular spasm B) fibrinolysis C) platelet plug formation D) coagulation
B
26) Adverse reaction of donor blood cells with recipient plasma. A) Hemoglobin B) Agglutination C) Monocyte D) Factor VIII E) Neutrophil
B
26) Which of the following is not a cause of bleeding disorders? A) thrombocytopenia, a condition of decreased circulating platelets B) excess secretion of platelet-derived growth factor (PDGF) C) a defect in the clotting cascade D) vitamin K deficiency
B
30) Liquid portion of the blood. A) Spectrin B) Plasma C) Thrombus D) Whole blood E) Water
B
33) Which of the following is a precursor of a basophil? A) megakaryoblast B) myeloblast C) lymphoblast D) monoblast
B
38) Released from platelets. A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
B
Using Figure 17.1, match the following: 1) Monocyte.
B
Using Figure 17.1, match the following: 8) Becomes a macrophage.
B
12) The most abundant plasma protein is ________. A) globulin B) clotting protein C) albumin D) bile
C
14) Largest of the WBCs; crucial in defense against viruses; associated with chronic infections. A) Basophil B) Eosinophil C) Monocyte D) Erythrocyte E) Neutrophil
C
14) Select the correct statement regarding blood cell formation. A) The main sites of blood cell production in adults are the spleen and the liver. B) Before the seventh month of fetal development, yellow marrow is the main site of blood cell formation. C) Red marrow is the main site of blood cell formation throughout adult life. D) Yellow marrow is the main site of leukocyte formation.
C
15) Blood volume restorers include all of the following except ________. A) dextran B) albumin C) packed cells D) saline solutions
C
17) Which of these is not a normal plasma protein? A) fibrinogen B) gamma globulin C) thromboplastin D) albumin
C
2) What is the average normal pH of blood? A) 8.4 B) 7.8 C) 7.4 D) 4.7
C
21) Any decrease in oxygen-carrying ability of the blood. A) Beta globulins B) Embolus C) Anemia D) Clotting
C
23) A lack of intrinsic factor, leading to a deficiency of vitamin B12 and large pale cells called macrocytes, is characteristic of ________. A) aplastic anemia B) polycythemia C) pernicious anemia D) sickle-cell anemia
C
24) White blood cell with dark-staining nucleus. A) Hemoglobin B) Agglutination C) Monocyte D) Factor VIII E) Neutrophil
C
28) Which of the following is true about blood plasma? A) It is the same as serum but without the clotting proteins. B) The main protein component is hemoglobin. C) It is about 90% water. D) It contains about 20 dissolved components.
C
3) The special type of hemoglobin present in fetal red blood cells is ________. A) hemoglobin A B) hemoglobin B C) hemoglobin F D) hemoglobin S
C
32) A clot that develops in an unbroken blood vessel. A) Spectrin B) Plasma C) Thrombus D) Whole blood E) Water
C
33) Stem cell from which all formed elements arise. A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
C
34) Sickling of red blood cells can be produced in those with sickle-cell anemia by ________. A) travel at high altitude B) vigorous exercise C) malaria and travel at high altitude D) travel at high altitude and vigorous exercise
C
Answer: A 25) Thromboembolic disorders ________. A) result in uncontrolled bleeding B) include thrombus formation, a clot in a broken blood vessel C) include embolus formation, a clot moving within the circulatory system D) are caused by vitamin K deficiency
C
Using Figure 17.1, match the following: 3) Eosinophil.
C
Using Figure 17.1, match the following: 7) Kills parasitic worms.
C
12) Transports CO2 and oxygen. A) Basophil B) Eosinophil C) Monocyte D) Erythrocyte E) Neutrophil
D
13) When neither anti-A nor anti-B clots on a blood plate, the blood is type ________. A) A B) B C) AB D) O
D
16) James has a hemoglobin measurement of 16 g/100 ml blood. This is ________. A) above normal B) normal only if James is an infant C) abnormally low D) within the normal range
D
22) Coagulation. A) Beta globulins B) Embolus C) Anemia D) Clotting
D
22) Place the following in correct developmental sequence: 1. reticulocyte 2. proerythroblast 3. normoblast 4. late erythroblast A) 1, 2, 3, 4 B) 1, 3, 2, 4 C) 2, 1, 3, 4 D) 2, 4, 3, 1
D
27) Lacking in hemophilia type A. A) Hemoglobin B) Agglutination C) Monocyte D) Factor VIII E) Neutrophil
D
29) Plasma and formed elements. A) Spectrin B) Plasma C) Thrombus D) Whole blood E) Water
D
34) Interferes with blood-clotting ability. A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
D
36) Found in basophils A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
D
36) When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother? A) if the child is type O positive B) if the child is Rh+ C) if the father is Rh+ D) if the father is Rh-
D
38) Blood is a ________. A) colloid B) homogeneous compound C) heterogenous compound D) suspension
D
40) The shelf life of whole collected blood at 4° C is about ________ days. A) 206 B) 120 C) 55 D) 35
D
5) Which blood type is called the universal donor? A) A B) B C) AB D) O
D
6) Which of the following is a regulatory function of blood? A) delivery of oxygen to body cells B) transport of metabolic wastes from cells C) prevention of blood loss D) maintenance of normal pH in body tissues
D
8) Which of the following is not a phase of erythropoiesis? A) production of ribosomes B) synthesis of hemoglobin C) ejection of the erythrocyte nucleus D) production of vacuoles
D
Using Figure 17.1, match the following: 2) Lymphocyte.
D
Using Figure 17.1, match the following: 6) Mounts an immune response by direct cell attack or via antibodies.
D
11) Nucleus is multilobed; functions as a phagocyte; contains fine indistinct granules. A) Basophil B) Eosinophil C) Monocyte D) Erythrocyte E) Neutrophil
E
23) Polymorphonuclear leukocyte. A) Hemoglobin B) Agglutination C) Monocyte D) Factor VIII E) Neutrophil
E
28) Constitutes 90% of plasma volume. A) Spectrin B) Plasma C) Thrombus D) Whole blood E) Water
E
37) Deficient erythrocyte production due to lack of intrinsic factor and failure to absorb vitamin B12. A) Erythropoietin B) Prostaglandin derivatives C) Hematopoietic stem cell D) Heparin E) Pernicious anemia
E
1) The primary source of RBCs in the adult human being is the bone marrow in the shafts of the long bones.
False
10) Each hemoglobin molecule can transport two molecules of oxygen.
False
11) Diapedesis is the process by which red blood cells move into tissue spaces from the interior of blood capillaries
False
14) Basophils increase in number when parasitic invasion occurs.
False
17) Leukocytes move through the circulatory system by amoeboid motion.
False
20) Myelocytic leukemia involves a cancerous condition of lymphocytes.
False
3) The immediate response to blood vessel injury is clotting.
False
4) The process of fibrinolysis disposes of bacteria when healing has occurred.
False
5) The RBC ʺgraveyardʺ is the liver.
False
8) Hemoglobin is made up of the protein heme and the red pigment globin.
False
12) Positive chemotaxis is a feedback system that signals leukocyte migration into damaged areas.
True
13) A condition of leukocytosis indicates over 11,000 white blood cells per cubic millimeter in the blood.
True
15) Leukopenia is an abnormally low number of leukocytes.
True
16) A person with type B blood could receive blood from a person with either type B or O blood.
True
18) Granulocytes called neutrophils are phagocytic and the most numerous of all white blood cell types.
True
19) All lymphocytes are leukocytes, but not all leukocytes are lymphocytes.
True
2) Leukemia refers to cancerous conditions of white blood cells.
True
6) Hemorrhagic anemias result from blood loss.
True
7) White blood cells are produced through the action of colony-stimulating factors.
True
9) Each heme contains an atom of iron and can transport one molecule of oxygen.
True
1) The formed element ________ can kill parasitic worms
eosinophil
2) A ________ is a committed granular leukocyte stem cell which produces neutrophils.
myeloblast
