Chapter 8- 214 Exam 3

The promoters for Eukaryotic mRNA synthesis:

-Are the stretches of DNA to which RNA polymerase binds to initiate transcription - Have specific DNA sequences such as the "TATA" box that are recognized by proteins. -Can require binding of multiple transcription factors and gene regulatory proteins to form a transcription complex. - Are more complex than prokaryotic promoters

How are most eukaryotic gene regulatory proteins able to affect transcription when their binding sites are far from the promoter?

By looping out the intervening DNA between their binding site and the promoter

In bacteria, the genes encoding ribosomal RNA, tRNA, and mRNA are transcribed by different RNA polymerases. TRUE or FALSE

FALSE

Most gene regulatory proteins work as monomers. TRUE or FALSE

FALSE

Riboswitches are made of ribosomal RNA. TRUE or FALSE

FALSE

Transcription is activated at the trp operon in the presence of the amino acid tryptophan. TRUE or FALSE?

FALSE

Which of the following is not involved in post-transcriptional control?

Mediator

Which one of the following is the main reason that a typical eukaryotic gene is able to respond to a far greater variety of regulatory signals than a typical prokaryotic gene or operon?

The transcription of a eukaryotic gene can be influenced by proteins that bind far from the promoter.

In principle, how many different cell types can an organism having four different types of gene regulatory proteins and thousands of genes create?

Up to 16

Specific interactions between DNA binding proteins and DNA

take place in the major groove where bases are exposed.

The distinct characteristics of different cell types in a multicellular organism are produced mainly by the differential regulation of the.....

transcription of genes transcribed by RNA polymerase II.

In bacteria, but not in eukaryotes, most mRNAs encode more than one protein. TRUE or FALSE

TRUE

Methylation of DNA attracts protein that block gene expression. TRUE or FALSE

TRUE

Of the major control points in gene expression (transcription, RNA processing, RNA transport, translation, and control of a protein's activity), transcription initiation is used for the vast majority of gene regulation events. TRUE or FALSE

TRUE