COVID-19 (SARS-CoV-2)

Treatments for COVID

Outside of hospital •Ibuprofen or acetaminophen for treating fever •Fluids to combat dehydration •Plenty of rest In hospital •Supplemental oxygen •Remdesivir - Slows viral replication •Dexamethasone - Steroid that will help control an overactive immune response •Blood thinners •Convalescent plasma/monoclonal antibodies - Can help reduce viral load although the evidence to support this treatment isn't strong.

Preventing the spread of COVID

The best way to protect yourself is to avoid getting or spreading COVID-19. •Stay 6 feet from others who don't live in your household •Wear a mask over your nose and mouth. •Avoid crowds and poorly ventilated places. •Wash your hands often. •Cover your coughs and sneezes. •Clean and disinfect frequently touched surfaces. •Monitor your health daily. Vaccinate •Pfizer •Moderna •Johnson and Johnson

Brief history of COVID 1

US deaths: 532,000 Global deaths: 2,630,000

Biology of SARs-CoV-2

•Enveloped virus •(+) ssRNA virus •Attached to cells via S protein •Utilizes human ACE2 receptor to gain entry into the host cell.

Brief history of COVID

•First index case of a novel corona virus identified in Wuhan (Dec, 2019) •Chinese scientist isolate the novel corona virus (Jan 7, 2020) •First cases found outside of China (Jan 13, 2020) •First cases of Covid-19 discovered in the US (Jan 21, 2020) •First Covid-19 death recorded in California (Feb 2, 2020) •Covid-19 declared a pandemic by the WHO (March 11, 2020)