Emesis

What is emesis?

Reverse peristalsis

Why was Victorias skin pale and damp?

Sympathetics Pale bc vasoconstriction Damp bc stimulates sweating

How do the sensory signals that elicit vomiting reach the emetic center in the brain?

The NTS receives afferent signals Sends signals to emetic center Emetic center coordinates somatic and autonomic components of vomiting reflex

What area in the brainstem detects bloodbourne toxins?

The area postrema, it is devoid of the blood brain barrier

Why was Victoria dizzy and weak?

CO2 is a metabolic dilator Victoria was hyperventilating, decrease CO2, therefore vasoconstrict to brain -> lightheadedness

What else can trigger vomiting center?

Higher centers resulting from fear or repulsion

What kind of acid base disturbance does vomiting cause?

Loss of acid, you become basic! Alkalosis

Prolonged vomiting leads to...

Loss of chloride ion Extracellular volume depletion Increased renin Increased aldosterone Potassium depletion Retention of bicarbonate

Which brainstem centers receive signals from the stomach?

NTS or vomiting center

Which brainstem center coordinates vomiting?

Requires cooperation of both the somatic and visceral musculature Coordinated by the emetic (vomiting) center, a loosely associated group of neurons located in the lateral RETICULAR FORMATION of the brain stem

What causes mouth to water and tearing?

Parasympathetics