Formation of Synapses

interactions between synapse and end plate

At the end of the formation of the neuromuscular junction, the numerous motor axons the try and terminate on a site all disappear except for one, leaving one last step for the junction to be complete which is:

schwann, astrocytes

At the neuromuscular function, ____________ cells promote synapse formation wheres as the glial cells that promote formation in the CNS are ___________

adhesion

__________ molecules in the pre and post synaptic terminals interact in a matchmaking exercise to form specific synapses in the CNS as they do not have the basal lamina of a muscle fibre

agrin, ACh

__________, which is synthesised by motor neurons binds MuSK receptors which produces signals to cluster ______ receptors at the neuromuscular junction.

motor axon

Differentiation of the post synaptic muscle membrane is dependent on signal from the ______________

axon, filopodium

During the formation axodedritic synapses, contact is made between an ________ and _____________ on a developing dendrite

acetylcholine, cytoplasmic

In the development of neuromuscular junctions, the only neurotransmitter present is ______________. In the CNS, _________________ proteins cluster receptors in a way that means the synapse can form according to a specific neurotransmitter, not all the ones bombarding it.

growth cone, myotubule

In the formation of the neuromuscular junction, a _______________ is guided towards developing skeletal muscle to approach a newly formed _____________

post-synaptic

Specific recognition molecules guide an axon to its ______________ target

acetylcholine

Synapses mature even postnatally where __________ receptors will change (in the case of neuromuscular junctions)

basal lamina

Whilst motor axons have intrinsic properties that imitate neurotransmission, the __________________ of the muscle gives signals to the nerve terminal to guide reinnervation