Gen Bio 1 Homework 11

You are an endocrinologist studying new treatments for prostate cancer. You have a patient with an unusually large level of dihydrotestosterone. Which of the following is true? While your patient may not be cured, he is in remission. Your patient is responding to treatment. Your patient is cured. Your patient's cancer has become resistant to the standard treatment.

Your patient's cancer has become resistant to the standard treatment.

Your uncle has prostate cancer. Which of the following indicates improvement in his condition? A PSA that varies throughout the day. An increasing PSA. A decreasing PSA. A PSA that remains elevated, but unchanged.

A decreasing PSA.

Researchers began a study of a cultured cell line. Their preliminary observations showed them that the cell line did not exhibit either density-dependent inhibition or anchorage dependence. What could they conclude right away? The cells have altered series of cell cycle phases. The cells are unable to form spindle microtubules. The cells show characteristics of tumors. The cells originated in the nervous system. The cells were originally derived from an elderly organism.

The cells show characteristics of tumors.

You are an oncologist. A patient presents with advanced prostate cancer and you follow standard protocol. What do you do? The patient undergoes radical surgery. The patient is treated with a high dose of radiation. Nothing - the patient cannot be helped. The patient is treated with chemical castration.

The patient is treated with chemical castration.

Prior to this new technique, how were mice given cancerous tumors? The tumors were implanted under the skin. The tumors were spliced into the organs of interest. The tumors were injected into the bone marrow. They were fed a tumor-causing substance.

The tumors were implanted under the skin.

Genetic tests determine if you do or don't have the BRCA gene. True False

False

The normal version of the BRCA gene causes breast cancer. True False

False

Women with the BRCA gene are at high risk for having aggressive types of breast and ovarian cancer. True False

False

For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable? It only attacks cells that are density dependent. It interferes with cells entering G0. It is safe enough to limit all apoptosis. It does not alter metabolically active cells. It interferes with rapidly dividing cells.

It interferes with rapidly dividing cells.

Which of the following is true regarding prostate cancer cells? They cannot activate or inactivate genes. They can inactivate genes, but cannot activate them. They can activate and inactivate certain genes. They can activate genes, but cannot inactivate them.

They can activate and inactivate certain genes.

Why do neurons and some other specialized cells divide infrequently? They no longer have active nuclei. They have been shunted into G0. They can no longer bind Cdk to cyclin. They show a drop in MPF concentration. They no longer carry receptors for signal molecules.

They have been shunted into G0.

What is true of all cancers? They are inherited. They are caused by chemical carcinogens. They have escaped normal cell cycle controls.

They have escaped normal cell cycle controls.

Everyone has the BRCA gene, even men. True False

True

Genetic tests determine what version of the BRCA gene you have. True False

True

Women with certain mutated versions of the BRCA genes are at high risk for having aggressive types of breast and ovarian cancer. True False

True

Which of these is NOT a carcinogen? fat UV light cigarette smoke testosterone all of the above are carcinogens

all of the above are carcinogens

One difference between cancer cells and normal cells is that cancer cells ________. are unable to synthesize DNA are arrested at the S phase of the cell cycle continue to divide even when they are tightly packed together cannot function properly because they are affected by density-dependent inhibition are always in the M phase of the cell cycle

continue to divide even when they are tightly packed together

_____ is a carcinogen that promotes colon cancer. fat UV light estrogen a virus testosterone

fat