HDFN

Today, amniocentesis is preferred to Doppler sonography for monitoring the severity of hemolytic disease of the fetus and newborn (HDFN). True/False

False

Which of the following is generally considered equivalent to CMV seronegative RBC for use in an exchange transfusion to a newborn?

Leukoreduced RBC

Which of the following must be true in order for a fetus to be at risk for hemolytic disease of the fetus and newborn (HDFN)?

The fetus must inherit a paternal red blood cell (RBC) antigen that is not present on maternal RBCs.

Which of the following blood group antibodies is generally NOT associated with HDFN?

Anti-Lea

At 28 weeks gestation, a group A Rh-negative female had a negative antibody screen and was injected with Rh immune globulin (RhIG). Anti-D is detected in the mother's serum at delivery. A panel is performed that excludes the presence of other antibodies. The most likely conclusion would be passive anti-D due to RhIG administration. True/False

True

The ability to produce anti-D varies significantly among Rh negative individuals. True/False

True

Tiny volumes of D+ red cells (eg, as little as 0.1 mL) can stimulate production of anti-D in some individuals. True/False

True

A 300 µg dose of RhIG will be protective for up to what volume of fetomaternal hemorrhage of WHOLE BLOOD?

30 mL

Which of the following consequences of severe hemolytic disease of the fetus and newborn (HDFN) is most associated with neonatal death before or shortly after birth?

Hydrops fetalis

A mother's serologic results are shown above. Her newborn types as group A Rh positive with a (1+) positive direct antiglobulin test (DAT). Which of the following investigative tests would be most useful to resolve the cause of the positive DAT and should be done FIRST?

Test newborn's plasma against group A1 red cells and group O antibody screen cells by IAT.