Histology of the Small and Large Intestine

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Goblet cells is the correct answer.

Question 10 1 / 1 pts A section of the jejunum (shown in the image) is stained for carbohydrate using periodic acid-Schiff (PAS). Parallel arrays of intestinal villi are examined at high magnification (shown in the image). Identify the PAS-positive cells revealed in this tissue. image007.jpg Goblet cells Parietal cells Histiocytes Paneth cells Chief cells

Paneth cells is the correct answer.

Question 11 1 / 1 pts A 55-year-old man undergoes abdominal surgery to remove a neuroendocrine tumor (carcinoid) of the small intestine. Normal intestinal mucosa at the margin of the tumor is embedded in plastic, sectioned at 1.5 um, and examined at high magnification. Identify the secretory cells within the box (shown in the image). image008.jpg Paneth cells Goblet cells Enterocytes Macrophages Plasma cells

Ileum is the correct answer.

Question 12 1 / 1 pts The internal organs of a 78-year-old woman who died of metastatic cancer are examined at low magnification. Identify the segment of the GI tract that is shown in the image. image009.jpg Jejunum Cecum Duodenum Ileum Rectum

Antigen uptake is the correct answer.

Question 13 1 / 1 pts During your examination of the specimen described in previous question, you are asked to discuss microfold (M) cells and mucosa-associated lymphoid tissue. What is the principal function of M cells in the distal ileum? Fluid transport Histamine release Gastrin secretion Antigen uptake Chemoreception

Crypts of Lieberkühn is the correct answer.

Question 14 1 / 1 pts The autopsy specimen in the first image below is examined at higher magnification. Identify the glandular structures located between the lines (shown in the second image). image009.jpg Below is a magnification of the above image. image010.jpg Fundic glands Cardiac glands Pyloric glands Crypts of Lieberkühn Brunner glands

Submucosa is the correct answer.

Question 15 1 / 1 pts Further examination of the first image below reveals arterioles and venules (arrows, shown in the second image). These blood vessels are located within which of the following layers of the GI tract? image009.jpg Below is a magnification of the above image. image011.jpg Muscularis externa Lamina propria Submucosa Adventitia Mucosa

Lamina propria is the correct answer.

Question 16 1 / 1 pts An intestinal villus is examined at high magnification. Goblet cells appear to be secreting mucus into the lumen of the gut (arrows, shown in the image). Macrophages and lymphocytes visible in this slide specimen are located primarily within which of the following layers of the GI tract? image012.jpg Muscularis externa Epithelium of mucosa Lamina propria Muscularis mucosae Submucosa

Enterocytes is the correct answer.

Question 17 1 / 1 pts During the seminar, you are asked to discuss the cellular mechanisms that mediate antibody transport across the epithelial barrier of the GI tract. Which of the following cells transports IgA from the lamina propria of the mucosa to the lumen of the gut? Plasma cells Goblet cells Paneth cells Microfold cells Enterocytes

Teniae coli is the correct answer.

Question 18 1 / 1 pts Various organs of the GI tract are examined at low magnification in the histology laboratory. Identify the structure indicated by the arrow (shown in the image). image013.jpg Adventitia Omental appendices Haustra coli Teniae coli Plicae circulares

Muscularis externa is the correct answer.

Question 19 1 / 1 pts Digital slides of the GI tract are examined in the histology laboratory. The double arrow (shown in the image) indicates which of the following layers of the large intestine? image014.jpg Muscularis mucosae Mucosa Muscularis externa Lamina propria Submucosa

Small intestine is the correct answer.

Question 2 1 / 1 pts A 70-year-old man undergoes chemotherapy for liver cancer, develops sepsis, and dies of multiorgan system failure. The patient's visceral organs are examined at autopsy. The plastic-embedded section shown in the image was obtained from what segment of the GI tract? image001.jpg Large intestine Stomach Appendix Esophagus Small intestine

Appendix is the correct answer.

Question 20 1 / 1 pts Your classmate opens a new digital slide and you study it together on the computer monitor. Identify the segment of the GI tract that is shown in the image. image015.jpg lleum Duodenum Jejunum Rectum Appendix

Enterocytes is the correct answer.

Question 21 1 / 1 pts A 69-year-old woman undergoes a routine colonoscopy. During the procedure, a 2-cm mass is identified and resected. Microscopic examination shows irregular crypts lined by a pseudostratified epithelium. Normal tissue is evident at the tumor margin (shown in the image). In addition to mucin-producing goblet cells, these normal colonic glands are composed of which of the following epithelial cells? image016.jpg Parietal cells Enterocytes Enteroendocrine cells Chief cells Paneth cells

Rectoanal junction is the correct answer.

Question 22 1 / 1 pts You are invited to shadow a GI pathologist. A surgical specimen is examined using a double-headed microscope. This normal tissue was obtained from which of the following locations in the GI tract? image017.jpg Rectoanal junction Esophagogastric junction Gastroduodenal junction lleocecal junction Colorectal junction

Lacteals is the correct answer.

Question 3 1 / 1 pts Examination of the lamina propria of the organ in the image show below reveals which of the following key histologic features of the GI tract? image001.jpg Meissner plexuses Brunner glands Pyloric glands Lacteals Myenteric plexuses

Chemoreception is the correct answer.

Question 4 1 / 1 pts A silver stain is used to identify enteroendocrine cells in the pyloric region of the stomach (small dark-stained cells, shown in the image). These argentaffin cells are classified as "open" or "closed" depending on whether or not their apical membranes reach the lumen of the gut. What is the primary function of "open" enteroendocrine cells in the GI tract? image002.jpg Histamine release Antigen uptake at is the primary function of "open" enteroendocrine cells in the GI tract? Chemoreception Gastrin secretion Antibody secretion

Duodenum is the correct answer. (but textbook says its stomach)

Question 5 1 / 1 pts Various GI organs are examined at a multiheaded microscope in the pathology department. The pathology resident asks you to comment on the glandular tissue located within the lines (shown in the image). These mucosal glands empty into which of the following segments of the GI tract? image003.jpg Colon Jejunum Duodenum Ileum Stomach

Brunner glands is the correct answer.

Question 6 1 / 1 pts Various organs of the GI tract are examined in the histology laboratory. Identify the glandular structures located between the double arrows (shown in the image). image004.jpg Pyloric glands Cardiac glands Brunner glands Fundic glands Intestinal glands

Bicarbonate ions is the correct answer.

Question 7 1 / 1 pts Which of the following is an essential secretory product of the submucosal glands identified in the image below? image004.jpg Lipase Hydrochloric acid Pepsinogen Amylase Bicarbonate ions

Plicae circulares is the correct answer.

Question 8 1 / 1 pts A 68-year-old man with a history of intestinal malabsorption suffers a stroke and expires. Portions of the patient's small intestine are collected at autopsy, stained with H&E, and examined at low magnification. Identify the distinctive submucosal folds indicated by the arrows (shown in the image). image005.jpg Villi Rugae Haustra Plicae circulares Teniae coli

Glycocalyx is the correct answer. (but textbook says it striated brush border)

Question 9 1 / 1 pts The autopsy specimen described in the previous question is examined at high magnification. Identify the delicate apical membrane feature indicated by the arrows (shown in the image). image006.jpg Glycocalyx Lamina densa Lamina propria Striated brush border Basal lamina

Epithelium of mucosa is the correct answer.

The gastrointestinal (Gl) tract is compartmentalized into organs that are specialized for digestion of food and absorption of nutrients. Most variation and specialization along the length of the GI tract occur in which of the following tissue layers? Epithelium of mucosa Muscularis mucosae Submucosa Lamina propria Muscularis externa


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