Lab Animal Final Study Guide

The Animal Welfare Act (AWA): A. only protects dogs and cats from being stolen and sold to research facilities. B. is the principle federal statute governing the sale, handling, and use of animals. C. was first passed in 1960. D. is under the jurisdiction of the IACUC.

.s the principle federal statue governing the sale, handling and use of animal

The recommended number of complete air changes for an animal room are: A. 4-8 per hour. B. 10-15 per hour. C. 20-25 per hour. D. 25-30 per hour.

10-15 per hour

The gestation period for a mouse is: A. 12-15 days. B. 19-21 days. C. 22-25 days. D. 26-28 days.

19-21 days

The gestation period for a rat is: A. approximately 15 days. B. approximately 19 days. C. approximately 22 days. D. approximately 24 days.

22 days

What is the minimum number of individuals that can be on the IACUC? A. 2 B. 3 C. 4 D. 5

3

Most animal rooms can be maintained with what range of relative humidity? A. 25% to 30% B. 30% to 50% C. 45% to 55% D. 50% to 70%

45-55%

The IACUC must have at least one of which of the following on the committee? A. A veterinarian with training and experience in laboratory animal medicine B. A researcher from the facility C. A layperson to speak for the community D. A lawyer

A veterinarian with train and experience in laboratory animalmedicine

What is the first level of certification for members of the research team? A. ALAT B. LAT C. LATG D. PI

ALAT

Which agency inspects research facilities on an annual basis? A. APHIS B. USDA C. REAC D. IACUC

APHIS

A veterinarian with an interest in laboratory animal medicine would benefit from being a member of: A. AALAS. B. the American College of Laboratory Animal Medicine. C. ASLAP. D. AVMA.

ASLAP

The organization that certifies laboratory animal veterinarians is the: A. American Association for Laboratory Animal Science (AALAS). B. American College of Laboratory Animal Medicine. C. American Society of Laboratory Animal Practitioners (ASLAP). D. American Veterinary Medical Association (AVMA)

American College of Laboratory Animal Medicine

Federal organizations that write and enforce laws regarding animals would be members of which group? A. Animal use group B. Animal exploitation group C. Animal control group D. Animal welfare group

Animal control group

An individual who believes that animals are strictly to be used by humans, who believes animals don't feel pain, or who has no concern for the animal if it was in pain would be likely to be a member of an: A. animal use group B. animal exploitation group C. animal control group D. animal welfare group

Animal exploitation group

An individual that advocates that animals should not be forced to work or produce for human benefit in any way and believe that animals should not be owned by a person are members of which group? A. Animal liberation group B. Animal exploitation group C. Animal control group D. Animal welfare group

Animal liberation group

An individual who firmly believes that animal research should never be done no matter what the purpose or value would be a member of which group? A. Animal use group B. Animal exploitation group C. Animal control group D. Animal rights group

Animal rights group

Individuals that like to hunt and fish, raise livestock, or go to zoos would fall into which group? A. Animal use group B. Animal exploitation group C. Animal control group D. Animal welfare group

Animal use group

A volunteer at a humane society or a rescue group would be considered a member of which group? A. Animal use group B. Animal exploitation group C. Animal control group D. Animal welfare group

Animal welfare group

The term laboratory animal refers to: A. any animal used in research or teaching. B. only mice and rats. C. only guinea pigs. D. any animal other than farm animals.

Any animal used in research

The legal definition of an exotic pet refers to: A. any companion animal other than a dog or a cat. B. any animal that is not a native to the area where it is housed. C. any pocket pet. D. only large cats and reptiles.

Any companion animal other than a dog

Which organization promotes the humane treatment of animals in science through a voluntary accreditation program? A. Office of Laboratory Animal Welfare (OLAW) B. American Association of Laboratory Animal Science (AALAS) C. National Institutes of Health (NIH) D. Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC)

Associaton for Assessment and Accreditation of Laboratory Animal Care (AAALAC)

How often should the facility be inspected and the programof veterinary care program be reviewed by the IACUC? A. At least every 3 months B. At least every 6 months C. At least every 9 months D. At least every 12 months

At least ever 6 months

Animals that are germ-free are generally housed in which type of facility? A. Containment facility B. Double-corridor facility C. Conventional facility D. Barrier facility

Barrier facility

Which type of facility contains an airlock in the entrance and may have ultraviolet lights within the airlock to sterilize equipment and supplies? A. Containment facility B. Double-corridor facility C. Conventional facility D. Barrier facility

Barrier facility

When considering the primary enclosures used for a specific species, which of the following is not a consideration? A. Be capable of containing the animal without unnecessary restraint B. Be able to hold as many animals as possible C. Be free from hazards and environmental stressors D. Allow for observation without disturbing the normal physiology and behavior of the animal

Be able to hold as many animals as possible

A researcher is proposing a study using Mycobacterium tuberculosis. What level of biosafety would this study require? A. Biosafety level I B. Biosafety level II C. Biosafety level III D. Biosafety level IV

Bio safety III

Animals that have highly zoonotic or infectious diseases should be housed in which type of facility? A. Containment facility B. Double-corridor facility C. Conventional facility D. Barrier facility

Contaminent facility

A new animal facility is being planned. What is the most important aspect of the design process? A. Designed for ease of entering and exiting the building B. Designed to minimize the spread of disease from one part of the facility to another C. Designed to hold as many animals as possible D. Designed for ease of work flow for employees

Designed to minimize the spread of disease from one part of the facility to another

What are the adverse effects if the air exchange requirements are too highin an animal room? A. A buildup of noxious odors B. Drafts may occur in the animal cages C. Air may be recirculated D. The HEPA filters may not be effective

Drafts may occur in the animal cages

Which agency can request that specific animal safety testing be conducted and remove products from the market or restrict use if the safety of the product cannot be adequately determined? A. The Food and Drug Administration (FDA) B. The Environmental Protection Agency (EPA) C. The Food, Drug, and Cosmetic Act D. The USDA

FDA

Dietary factorscan have an effect on an animal and predispose it to diseases. Which of the following are dietary factors? A. Temperature, humidity, lighting, and noise B. Species, age, gender, and heredity C. Food and water quality and food and water containersanitation D. Surgery, restraint, and drug effects

Food, water quality, food and water sanitation

The primary reference on animal care and use is the: A. AWA B. Guide for the Care and Use of Laboratory Animals C. Animal Use Protocol D. Public Health Services (PHS) policy

Guide for the care and use of laboratory animals

Which entity is responsible for all aspects of animal use, education, health, and compliance with the laws and regulations within a facility? A. APHIS B. USDA C. REAC D. IACUC

IACUC

What isthe highest level of certification for members of the research team? A. ALAT B. LAT C. LATG D. PI

LATG

The AWA: A. has no requirements for exercise for dogs. B. has no requirements for enrichment for nonhuman primates (NHPs). C. mandates that any procedure that may have the potential for pain requires the use of analgesics, anesthetics,and tranquilizers. D. does not require the investigation for alternatives to animal use.

Mandates that any procedure that may have the potential for pain requires the use of analgesic, anesthetics, and tranquilizers

A research protocol requires the collection of urine and feces to access the total volume produced per animal per day. What is the best type of cage to use for this study? A. Gang cages B. Metabolism cages C. Suspended cages D. Shoebox cages

Metabolism cages

An animal room used to quarantine infectious animals should be maintained with: A. positive air pressure. B. ultraviolet lights. C. negative air pressure. D. at least 20 air exchanges an hour.

Negative air pressure

The organization responsible for enforcing laws that protect workers from workplace hazards is: A. Centers for Disease Control (CDC). B. Occupational Safety and Health Administration (OSHA). C. National Institutes of Health (NIH). D. Public Health Service (PHS).

OSHA

The CDC and NIH publication that defines specific procedures for working with hazardous materials is the: A. Biosafety in Microbiological and Biomedical Laboratories. B. Occupational Health and Safety in the Care and Use of Research Animals. C. Animal use protocol. D. Guide for the Care and Use of Laboratory Animals.

Occupational Health and Safety in the Care and Use of Research Animals

A facility needs new caging for rats. They are interested only in the strongest, most transparent cages. What material should they purchase? A. Polystyrene B. Polypropylene C. Stainless steel D. Polycarbonate

Polycarbonate

When designing a research facility, it is important to consider which feature in the design of the surgical suite? A. Positive air pressure B. Ultraviolet lights C. Negative air pressure D. At least20 air exchanges an hour

Positive air pressure

The research team leader is the: A. Assistant Laboratory Animal Technician (ALAT). B. Laboratory Animal Technician (LAT). C. Laboratory Animal Technologist (LATG). D. Principal Investigator (PI)

Principal investigator (PI)

If a research facility is found in violation of the AWA, which organization has the authority to enforce penalties for the violations? A. APHIS B. USDA C. REAC D. IACUC

REAC

Which species is covered under the AWA? A. Snakes B. Fish C. Rats D. Rabbits

Rabbits

A postsurgical patient may be placed in which type of cage to provide strict control of the temperature, humidity, oxygen pressure, and the availability of IV lines incorporated into the design? A. Metabolism cage B. Inhalation cage C. Transport cage D. Recovery cage

Recovery cage

The use of the absolute least number of animals that will achieve the research goals is referred to as: A. refinement. B. recycle. C. reduction. D. replacement.

Reduction

The term that refers to ensuring the experimental procedure causes the least amount of stress, pain, anxiety, and disturbance to the normal life of the animal and still reaches the goal is: A. refinement. B. recycle. C. reduction. D. replacement.

Refinement

When a scientist has deduced that an experimental model could be conducted on tissue cultures instead of rats it would be an example of: A. refinement. B. recycle. C. reduction. D. replacement.

Replacement

When an experiment can be conducted using a lower life form, a computer model, or other artificial means it is referred to as: A. refinement. B. recycle. C. reduction. D. replacement.

Replacement

A baby wild animal is found in a nest. Which of the following is the correct advice to give the client that calls about the animal? A. Don't touch it-the mother will reject a baby if touched by a human. B. If he or she hasn't seen a mother in 3-4 hours the baby has been abandoned. C. Return the animal to the nest unless it appears weak or is obviously injured. D. It is okay to keep the baby and try to hand raise it.

Return the animal to the nest unless it appears weak and is obviously injred

Which agency is focused on promoting integrity in biomedical and behavioral research and oversees institutional investigations into research misconduct? A. The USDA B. The IACUC C. The ILAR of the NAS D. The Office of Research Integrity

The Office of Research Integrity

Which area of the animal facility should have a clean and a dirty side and be as far away from the animal rooms as possible? A. The surgical suite B. The cage-washing rooms C. The employee access room D. The laboratory

The cage-washing rooms

Ensuring that all of the staff are trained correctly and appropriate records are kept within a laboratory animal facility is the responsibility of: A. the PI. B. the LATG. C. the laboratory veterinarian. D. the facility administrator.

The facility administrator

Which area for the facility must have temperature and humidity control and contain shelves or pallets? A. The surgical suite B. The cage-washing rooms C. The feed storage room D. The changing and shower rooms

The feed storage room

Which of the following applies to the use of farm animals used in nonbiomedical research protocols? A. AWA B. The Guide for the Care and Use of Laboratory Animals C. The Animal Use Protocol D. The Guide for the Care and Use of Agricultural Animals in Research and Teaching

The guide for the care and use of agricultural animals in research and teaching

An animal technician enters a room housing gerbils with a rack of cages. The room is brightly lit and warmer than normal with a low humidity. The technician notices that several of the animals appear to be having seizures. What may have caused the seizures? A. The bright lights in the room B. High temperature of the room C. Low humidity of the room D. The noise of the cage rack

The noise of the cage rack

A wild animal is brought into a clinic for emergency treatment. Once the animal is stabilized the veterinarian should: A. release the animal to the person who brought it into the practice. B. transfer the animal to a licensed rehabilitator as soon as possible. C. return the animal to nature and let nature take its course. D. keep the animal until it fully recovers.

Transfer the animal to a license rehabilitate as soon as possible

Which of the following is authorized by law to enforce animal welfare regulations? A. Animal and Plant Health Inspection Service (APHIS) B. United States Department of Agriculture (USDA) C. Regulatory Enforcement and Animal Care (REAC) D. Institutional Animal Care and Use Committee (IACUC)

USDA

Developing a new surgical procedure would be defined as: A. basic research. B. applied research. C. clinical research. D. research design

applied research

In which type of research is the choice of a specific research model based on the ability of the model to mimic or predict the response(s) in other species? A. Basic research B. Applied research C. Clinical research D. Research design

applied research

One of the disadvantages of which type of watering system is the inability to measure the water consumption of an individual animal? A. Bottle B. Bowl C. Automatic D. Tanks

automatic

An animal that is delivered naturally but has lived its entire life in a sterile, controlled environment would be classified as: A. axenic. B. gnotobiotic. C. specific pathogen-free. D. barrier-sustained.

axenic

An animal that was cesarean derived and lived its entire live in a sterile, controlled environment would be classified as: A. axenic. B. gnotobiotic. C. specific pathogen-free. D. barrier-sustained.

barrier-sustained

Research that is concerned with advancing the fundamental knowledge ofphysical, chemical, and functional mechanisms of life processes and disease is: A. basic research. B. applied research. C. clinical research. D. research design.

basic research

Because rats have a unique ability to adapt to new environments they are a good animal model for: A. oncology research. B. teratology research. C. behavioral research. D. immunology research

behavioral research

A research study involving a vaccine for canine infectious hepatitis virus would be considered a: A. biosafety level I. B. biosafety level II. C. biosafety level III. D. biosafety level IV.

bio safety I

A research protocol that involves Salmonella organisms would be considered a: A. biosafety level I. B. biosafety level II. C. biosafety level III. D. biosafety level IV.

bio safety II

The individuals assigned to the IACUC are appointed by: A. the researchers within the facility. B. chief executive officer (CEO) of the facility. C. the staff veterinarian. D. the USDA

chief executive officer CEO of the facility

Secretion of porphyrin is also called: A. hypsodontic. B. chromodacyorrhea. C. fecundity. D. Whitten effect.

chromodayorrhea

The Food and Drug Administration mandates that all new medications undergo which type of research? A. Basic research B. Applied research C. Clinical research D. Research design

clinical research

Which type of research must be conducted on a live animal? A. Basic research B. Applied research C. Clinical research D. Research design

clinical research

Because of the similarityof the rat molar to humans, the rat is often used in which type of research studies? A. Oncology B. Dental C. Teratology D. Gerontology

dental

What is the recommended type of light system for animal rooms? A. Daylight through windows B. Diurnal illumination C. Daylight blue fluorescent lights D. Soft white fluorescent light

diurnal illumination

In every animal room in this type of facility there are two doors, one for entering and one for exiting the room. What type of facility would this be? A. Containment facility B. Double-corridor facility C. Conventional facility D. Barrier facility

double corridor facility

Adding a resting ledge to a cage for a cat would be an example of: A. adding space requirements. B. environmental enrichment. C. an exercise program. D. an activity cage.

environmental enrichment

Due to the fact that rats do not have which organ does bile continuously enter the duodenum? A. Epiglottis B. Pancreas C. Gallbladder D. Cecum

gallbladder

A researcher needs animals that have a well-defined microflora with specific organisms and only those microorganisms present. How are these animals classified? A. Axenic B. Gnotobiotic C. Specific pathogen-free D. Cesarean derived

gnotobiotic

The secretions of which gland are often referred to as red tears? A. Retroorbital gland B. Cranial gland C. Venous plexus gland D. Harderian gland

harderian gland

Rats have a large store of brown fat around the neck and scapulae that provides 10 times the energy of other types of fat. What is this tissue called? A. Adipose tissue B. Hibernation tissue C. Porphyrin D. Fecundity

hibernation tissue

Which term means that rats' and mice's teeth will continuously grow throughout their life? A. Hypsodontic B. Chromodacyorrhea C. Fecundity D. Whitten effect

hypdodontic

A theory based on current knowledge that could answer a specific question or provide a solution is called a(n): A. idea. B. hypothesis. C. standard operating procedure (SOP). D. study design.

hypothesis

Which unique feature of rats makes them a good animal model for toxicology research? A. The liver has four lobes B. A monogastric stomach C. A highly diffuse pancreas D. The inability to vomit

inability to vomit

Temperature, humidity, lighting, and ventilation within a facility comprise the: A. microenvironment. B. conventional facility. C. macroenvironment. D. thermoneutral zone.

macroenvironment

The temperature, humidity, lighting, and ventilation of the cages at the bottom of a rack of cages may be different from those at the top of the rack. These factors are referred to as the: A. microenvironment. B. conventional facility. C. macroenvironment. D. thermoneutral zone.

microenvironment

The taxonomic name for the laboratory mouse is: A. Peromyscus sp. B. Mus musculus. C. Apodemus sylvaticus. D. Micromys minutus.

mus musculus

The red-pigmented substance that is discharged near the eyes in ill or animals under stress is: A. porphyrin. B. tears. C. adipose. D. bile.

porphyrin

An animal that is acquired from a USDA Class A dealer would also be known as: A. random source. B. hybrid. C. purpose-bred. D. purebred.

purpose-bred

Which of the following is a result of the epiphyses of the bones that do not close in most rats? A. Marrow is replaced with fat in older rats. B. Rats grow continuously throughout their life. C. The bones are extremely fragile and fracture easily. D. The marrow of the long bones remain active throughout life.

rats grow continuously throughout life

The taxonomic name for the most common rat used in biomedical research is: A. Rattus sp. B. Neotoma sp. C. Oryzomys sp. D. Sigmondon sp.

rattus sp.

A method of quality assurance in an animal facility is to periodically collect serologic, fecal, and blood for testing to identify the presence of microorganisms. What type of animal is used for this testing? A. Axenic B. Gnotobiotic C. Sentinel D. Barrier-sustained

sentinel

Predisposing factors referred to as intrinsic factors that can affect animal health are: A. temperature, humidity, lighting, and noise. B. species, age, gender, and heredity. C. food and water quality. D. surgery, restraint, and drug effects.

species, age, gender and heredity

A researcher is interested in acquiring animals that are free of certain pathogens but is not too concerned if the animal has additional pathogens other than those specified. What classification of animal is this? A. Axenic B. Gnotobiotic C. Specific pathogen-free D. Barrier-sustained

specific pathogen free

Rats and mice are: A. induced ovulators. B. spontaneous ovulators. C. seasonal ovulators. D. monestrous.

spontaneous ovulators

A facility needs new caging for dogs. They want the strongest material available that will be resistant to rust and cleaning chemicals. What type of caging material should they purchase? A. Aluminum B. Stainless steel C. Galvanized metal D. Polystyrene

stainless steel

Examples of experimental factors that predispose an animal to disease are: A. temperature, humidity, lighting, and noise. B. species, age, gender, and heredity. C. food and water quality. D. surgery, restraint, and drug effects.

surgery, restraint and drug effects

Extrinsic predisposing factors are: A. temperature, humidity, lighting, and noise. B. species, age, gender, and heredity. C. food and water quality and food and water container sanitation. D. surgery, restraint, and drug effects.

temperature, humidity, lighting, and noise

When a female is exposed to a new male within four days of breeding, the existing pregnancy may be aborted and the female returns to estrus. This is referred to as: A. the Bruce effect. B. intensive breeding. C. the Whitteneffect. D. nonintensive breeding.

the Bruce effect

When exposed to a male or the scent of a male, the females will begin estrus within three days. This is referred to as: A. the Bruce effect. B. intensive breeding. C. the Whitten effect. D. nonintensive breeding.

the Whitten effect

The Guide for the Care and Use of Laboratory Animals is written under the direction of: A. the USDA B. the IACUC C. the Institutefor Laboratory Animal Research (ILAR) of the National Academy of Sciences (NAS) D. the PHS

the institute for laboratory animal research (ILAR) of the National Academy of Sciences (NAS)

The range of temperature when an animal does not need mechanisms to produce or lose heat is the: A. microenvironment. B. conventional facility. C. macroenvironment. D. thermoneutral zone.

thermoneutral zone

A shoebox rodent cage usually contains a specific lid designed for feeding. What type of feeder is this? A. V-shaped B. J-shaped C. Slotted D. Bowl

v-shaped feeder