LAT EXAM PREP

How many Institutional Animal Care and Use Committee (IACUC) members are required by the Animal Welfare Regulations (enforced by the United States Agricultural Department)?

3

What is a grant application?

A document used to request research money

How often do the Animal Welfare Regulations require the IACUC to monitor the animal care and use program through reviews of the program and routine inspections of the animal facilities?

At least every 6 months

How often must an APHIS inspector conduct an unannounced site visit of the laboratory animal facility?

At least once a year

IACUCs are mandated by which of the following a. Federal mandate b. City ordinance c. State law d. Institutional policy

Federal mandate

The PHS Policy on Humane Care and Use of Laboratory Animals applies specifically to which type of research?

Federally funded research

Which of the following is NOT a role of the Principal Investigator?

Coordinating animal care activities

Before a new drug is tested on human subjects, the drug is tested on animals in a phase that is called ___________ testing.

Preclinical

The Animal Welfare Regulations require that protocols for United States Department of Agriculture (USDA)-covered species may only be approved for how long?

1 Year

Depending on the species and the institutional policies, for how long are protocols approved?

1-3 Years

Who is NOT required by the Animal Welfare Regulations (AWR) to be on the Institutional Animal Care and Use Committee (IACUC)?

A practicing Scientist

What is research?

A systematic investigation into the practices of the facility

Through the AALAS Certification Program, technicians become nationally certified. Name the three levels of technician certification.

ALAT, LAT, LATG

Which document outlines the appropriate methods for the humane killing of research animals?

AVMA Guidelines for the Euthanasia of Animals

What does the Institutional Animal Care and Use Committee (IACUC) have the authority to do? a. Approve animal care and use protocols b. Deny an investigator permission to begin a research project c. Stop a previously approved protocol d. All of the above

All of the above

In 1967, the Animal Care Panel changed its name to what?

American Association for Laboratory Animal Science

What step must occur before a research study using animals begins?

An animal use protocol must be approved by the Institutional Animal Care and Use Committee (IACUC)

Which of the following requires that protocols for United States Department of Agriculture (USDA)-covered species may only be approved for 1 year?

Animal Welfare Regulations (AWR)

Who administers the Animal Welfare Regulations?

Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA)

Which of group was established in 19050 to ensure welfare of laboratory animal and to provide for their needs?

Animal Care Panel

What regulation specifically protects employees who report significant deficits in a research program?

Animal Welfare Act

Which would NOT be an appropriate method to deal with interpersonal conflict in the workplace?

Avoid talking to the other person and request a transfer to another work area.

What is the best way for a research facility to avoid disruption of research by animal rights groups?

Compliance with all state, federal, and institutional regulations.

What is the first step in scientific research?

Define the question to be investigated

Which of the following is NOT a role for vendors and suppliers in the conduct of research?

Generating data to present to the scientific community

Due to anatomical similarity with humans, pigs are used to investigate diseases of which organs?

Heart

AT most institutions, who must review and monitor the animal use protocols at an institution?

Institutional Animal Care and Use Committee

What is the correct name for the acronym IACUC?

Institutional Animal Care and Use Committee

Which of the following reviews the animal use protocols of research projects to ensure compliance with all relevant federal, state, and local laws, regulations, and institutional policies on animal welfare?

Institutional Animal Care and Use Committee (IACUC)

Which member of the research team coordinates animal care activities and advises on the selection of appropriate animal models?

Laboratory animal veterinarian

Which of the following is NOT a career opportunity offered by a qualification in laboratory animal care?

Pharmaceutical sales

What is the name of the program that helps to ensure that IACUC-approved procedures are being followed?

Post-approval monitoring program

Which member of the research team plans and coordinates all phases of the research work?

Principal investigator

Which mandate requires five Institutional Animal are and Use Committee (IACUC) members?

Public Health Service (PHS) Policy

Which statement about the Registry is False?

Registry status is assessed every year

Using cell or tissue culture or mathematical models in the experiment is an example of which of the 3Rs principles?

Replacement

Which of the following is NOT a critical animal care function performed by lab animal technicians?

Setting the ventilation rate for the vivarium

Which of the following is NOT a benefit of stringently following SOPs?

Speed

What does the acronym "SOP" stand for?

Standard Operating Procedure

Which of the following duties would NOT be routinely performed by an ALAT?

Surgical Procedures

What mandate or document must be studied in addition to the ALAT Training Manual to prepare for the ALAT technician certification examination?

The Guide for the Care and Use of Laboratory Animals

If an allegation of misuse or mistreatment of animals cannot be resolved by facility management, to whom should the ALAT report their concerns?

The IACUC chair

Overall maintenance of the animal colony's health and regulatory compliance are the responsibility of which member of the research team?

The Laboratory Animal Veterinarian

Why are animals used to study human disease?

The physiological processes in animal models can be very similar to humans

Which of the following is the task of the post-approval monitoring program (PAM)?

To ensure that Institutional Animal Care and Use Committee (IACUC)-approved procedures are being followed.

What is the purpose of Good Laboratory Practices regulations?

To validate and document the process by which safety tests are conducted so that the processes can be reconstructed if needed.

What is NOT a method used by researchers to reduce the number of animals used?

Using invertebrates rather than mammals

Specific legal protections for employees who discover and report issues on noncompliance are also known as what?

Whistleblower laws