LS7B MTI exam review extra practice
a) 1/8 You use the "and" rule and multiply the probability of each event. There is a 1/2 probability that the off spring will be wrinkled so you cube it for three events
Among the progeny of a heterozygous round (Aa) x homozygous wrinkled (aa) test cross, three seeds are chosen at random. What is the probability that all three seeds are wrinkled? a) 1/8 b) 1/6 c) 1/4 d) 1/3 e) 1/2
D. 1/2
Blood type is characterized by the combination of alleles that an individual has at two different loci. Three alleles (I^A, I^B, and i) encode ABO blood group antigens. There are two co-dominant alleles (L^M and L^N) encode another set of antigens, the MN blood group (homozygous L^M individuals have type M, homozygous L^N individuals have type N, and heterozygous L^M L^N individuals have type MN). For the crosses below, what is the probability that a child will have a unique blood genotype (at BOTH loci) that is not the same as the blood group genotypes of either parent? I^A I^B L^M L^N x i i L^M L^N A. 0 B. 1/8 C. 1/4 D. 1/2 E. 1
A. 0
Blood type is characterized by the combination of alleles that an individual has at two different loci. Three alleles (I^A, I^B, and i) encode ABO blood group antigens. There are two co-dominant alleles (L^M and L^N) encode another set of antigens, the MN blood group (homozygous L^M individuals have type M, homozygous L^N individuals have type N, and heterozygous L^M L^N individuals have type MN). For the crosses below, what is the probability that a child will have a unique blood genotype (at BOTH loci) that is not the same as the blood group genotypes of either parent? I^A i L^M L^N x i i L^M L^N A. 0 B. 1/8 C. 1/4 D. 1/2 E. 1
False: The mother would need to have at least one i in her genotype
If this couple had a third child, one possible phenotype for that child is blood type O.
True: This would be with the assumption that there is crossover
In a diploid individual, one chromosome carries A and B alley, and the homologous chromosome carries a and b allele of the same genes. True or False: Meiosis in this individual could produce the four gametes AB, Ab, aB, ab.
True: based on the premise of linked genes
In a diploid individual, one chromosome carries A and B alley, and the homologous chromosome carries a and b allele of the same genes. True or False: Meiosis in this individual could produce the four gametes AB, AB, ab, ab.
False: Even in the event of a cross over, only 50% of the alleles would be able to cross over.
In a diploid individual, one chromosome carries A and B alley, and the homologous chromosome carries a and b allele of the same genes. True or False: Meiosis in this individual could produce the four gametes Ab, Ab, aB, aB.
C. Both situations are equally likely
In the pedigree shown here, males I-1 and III-2 have hemophilia (darkly shaded squares) and males II-1, II4, and III-1 are red-green color blind (lightly shaded squares). There are no males in the pedigree who have both conditions. Both of these traits are X-linked recessive. If these two genetic loci are so far apart that they always recombine, which of the two situations described below is more likely? Situation 1: II-1 and II-2 have a. third son with color blindness but not hemophilia Situation 2: II-1 and II-2 have a third son with hemophilia but not color blindness A. Situation 1 is more likely B. Situation 2 is more likely C. Both situations are equally likely
C. She is a carrier of both mutations, carrying one mutation on each of her two homologous chromosomes
In the pedigree shown here, males I-1 and III-2 have hemophilia (darkly shaded squares) and males II-1, II4, and III-1 are red-green color blind (lightly shaded squares). There are no males in the pedigree who have both conditions. Both of these traits are X-linked recessive. Which of the following statements must be true about individual II-2? A. She is a carrier of the hemophilia mutation but not the color-blindness mutation. B. She is a carrier of the color-blindness mutation but not the hemophilia mutation. C. She is a carrier of both mutations, carrying one mutation on each of her two homologous chromosomes D. She is a carrier of both mutations, carrying both mutations on the same chromosome
False
Porphyria is an autosomal dominant disease that disrupts how oxygen-binding molecules in red blood cells are produced. To help with genetic diagnosis, a VNTR near the porphyria locus is used to detect three possible VNTR alleles. Below is a pedigree from a family affected by porphyria, where shaded symbols (individuals Fa, 2 and 4) indicate an affected individual and their associated VNTR analysis. True or False: Of the three VNTR alleles, A3 has the greatest number of tandem repeats.
True
Porphyria is an autosomal dominant disease that disrupts how oxygen-binding molecules in red blood cells are produced. To help with genetic diagnosis, a VNTR near the porphyria locus is used to detect three possible VNTR alleles. Below is a pedigree from a family affected by porphyria, where shaded symbols (individuals Fa, 2 and 4) indicate an affected individual and their associated VNTR analysis. For each statement below mark A for True or B for False. True or False: The A1 allele is linked with the mutant allele in the father.
False
Porphyria is an autosomal dominant disease that disrupts how oxygen-binding molecules in red blood cells are produced. To help with genetic diagnosis, a VNTR near the porphyria locus is used to detect three possible VNTR alleles. Below is a pedigree from a family affected by porphyria, where shaded symbols (individuals Fa, 2 and 4) indicate an affected individual and their associated VNTR analysis. For each statement below mark A for True or B for False. True or False: The A2 allele is linked with the mutant allele in the mother.
False
Porphyria is an autosomal dominant disease that disrupts how oxygen-binding molecules in red blood cells are produced. To help with genetic diagnosis, a VNTR near the porphyria locus is used to detect three possible VNTR alleles. Below is a pedigree from a family affected by porphyria, where shaded symbols (individuals Fa, 2 and 4) indicate an affected individual and their associated VNTR analysis. For each statement below mark A for True or B for False. True or False: The A3 allele is linked with the mutant allele in the father.
False: If this were the case, the children would either be blood type AB or AA
Recall that ABO blood groups exhibit a co-dominant pattern of inheritance: I^A and I^B. A family has recently come in for a blood type test. The mother is blood type AB and her two children are both blood type B. True or False: The father's genotype could be I^A I^A.
True
Recall that ABO blood groups exhibit a co-dominant pattern of inheritance: I^A and I^B. A family has recently come in for a blood type test. The mother is blood type AB and her two children are both blood type B. True or False: The father's genotype could be I^A I^B.
True
Recall that ABO blood groups exhibit a co-dominant pattern of inheritance: I^A and I^B. A family has recently come in for a blood type test. The mother is blood type AB and her two children are both blood type B. True or False: The father's genotype could be I^B I^B.
True
Recall that ABO blood groups exhibit a co-dominant pattern of inheritance: I^A and I^B. A family has recently come in for a blood type test. The mother is blood type AB and her two children are both blood type B. True or False: The father's genotype could be i i.
True
The affected female in the pedigree below has Turner syndrome, a genetic condition that results when a child is born with a single X chromosome and no Y chromosome. A and B refer to co-dominant alleles of the X-linked G6PD gene. The phenotypes of each individual (A, B, or AB) are shown in the pedigree. Use the pedigree to answer each of the following questions. True or False: Nondisjunction could have occurred in meiosis 1 of the father.
True
The affected female in the pedigree below has Turner syndrome, a genetic condition that results when a child is born with a single X chromosome and no Y chromosome. A and B refer to co-dominant alleles of the X-linked G6PD gene. The phenotypes of each individual (A, B, or AB) are shown in the pedigree. Use the pedigree to answer each of the following questions. True or False: Nondisjunction could have occurred in meiosis 1 of the mother.
True
The affected female in the pedigree below has Turner syndrome, a genetic condition that results when a child is born with a single X chromosome and no Y chromosome. A and B refer to co-dominant alleles of the X-linked G6PD gene. The phenotypes of each individual (A, B, or AB) are shown in the pedigree. Use the pedigree to answer each of the following questions. True or False: Nondisjunction could have occurred in meiosis 2 of the father.
True
The affected female in the pedigree below has Turner syndrome, a genetic condition that results when a child is born with a single X chromosome and no Y chromosome. A and B refer to co-dominant alleles of the X-linked G6PD gene. The phenotypes of each individual (A, B, or AB) are shown in the pedigree. Use the pedigree to answer each of the following questions. True or False: Nondisjunction could have occurred in meiosis 2 of the mother.
True or False: The trait shown in this pedigree could be autosomal dominant.
True
True
True or False: A single human cell in metaphase I should contain 4 physical copies of the BRCA1 locus.
False: Box 3 only has one chromatid
True or False: Box 3 contains sister chromatids
False: All four would be affected. Two would have double the normal genes and two wouldn't have any.
True or False: Nondisjunction in meiosis I would lead to chromosome abnormalities in two out of the four resulting gametes.
True
True or False: Nondisjunction in meiosis I would put all the genetic material in Box 4 into only one of the four resulting gametes.
True
True or False: Nondisjunction in meiosis II would lead to chromosomal abnormalities in two out of four gametes.
False?
True or False: Recombination of genetic material within Box 1 will increase genetic variation in the gametes.
False: An affected father wouldn't be able to pass on the X allele to his direct son, only his daughter
True or False: The trait shown in this pedigree could be X-linked dominant.
False: The cross between an affected mother and an unaffected father could not result in an affected daughter.
True or False: The trait shown in this pedigree could be X-linked recessive.
True
True or False: The trait shown in this pedigree could be autosomal recessive.
D. c,e,a,d,b
Use the recombination frequencies listed below to map five SNP loci (a, b, c, d, e) onto a single chromosome: recombination frequency of a-b equals 17% recombination frequency of d-e equals 21% recombination frequency of c-e equals 9% recombination frequency of b-d equals 5% recombination frequency of a-d equals 12% recombination frequency of a-c equals 18% Based on the results above, in what order do these SNPs occur along the chromosome? A. a,b,c,d,e B. c,e,d,a,b C. a,c,e,d,b D. c,e,a,d,b E. a,e,c,d,b
E. 35 m.u.
Use the recombination frequencies listed below to map five SNP loci (a, b, c, d, e) onto a single chromosome: recombination frequency of a-b equals 17% recombination frequency of d-e equals 21% recombination frequency of c-e equals 9% recombination frequency of b-d equals 5% recombination frequency of a-d equals 12% recombination frequency of a-c equals 18% What is the distance, in map units, between SNPs b and c? A. 5 m.u. B. 12 m.u. C. 17 m.u. D. 21 m.u. E. 35 m.u.
E. 9%
Use the recombination frequencies listed below to map five SNP loci (a, b, c, d, e) onto a single chromosome: recombination frequency of a-b equals 17% recombination frequency of d-e equals 21% recombination frequency of c-e equals 9% recombination frequency of b-d equals 5% recombination frequency of a-d equals 12% recombination frequency of a-c equals 18% What recombination rate would you predict for SNPs a and e? A. 35% B. 30% C. 18% D. 12% E. 9%
B. 30%
Use the recombination frequencies listed below to map five SNP loci (a, b, c, d, e) onto a single chromosome: recombination frequency of a-b equals 17% recombination frequency of d-e equals 21% recombination frequency of c-e equals 9% recombination frequency of b-d equals 5% recombination frequency of a-d equals 12% recombination frequency of a-c equals 18% What recombination rate would you predict for c-d? A. 35% B. 30% C. 18% D. 12% E. 9%
D. Individual 4
Which individual indicates a recombination event between the marker allele and the dominant trait? A. Individual 1 B. Individual 2 C. Individual 3 D. Individual 4 E. Individual 5
