Pharmacology Ch 8 Bank

which of the following is the correct dosage for clotrimazole troche a. 5mg b. 10 mg c. 20 mg d. 25 mg

10 mg

HSV-1 lesions are self limiting and will resolve within _____ days.

10-14

The centers for Disease control defines AIDS as a CD4 count of a. > 200/µ L. b. <200/µ L. c. >2000/µ L. d. <100/µ L.

<200/µ L

The goal of HAART therapy is to reduce HIV RNA to: a. <50 copies/ML b. <100 copies/mL c. >1000 copies/mL d. .1500 copies/mL

<50 copies/mL

antifungal agent used for recurrant herpes labiallis

Acyclovir

which of the following antiretroviral drugs causes oral numbness a. amprevavir (agenerase) b. atazanavir (reyataz) c. nevirapine (viramune) d. delavirdine (rescriptor)

Amprevavir

Which of the following antiretroviral drugs can cause dental pain a. fosamprenavir b. atazanavir c. Indinavir d. Nelfinavir

Atazanavir

During an oral examination of a patient with a maxillary denture the hygienist notes that the palatal tissue is very red and shiny following the outline of the denture. How should the hygienist manage this problem? a. tell the patient everything is fine. b. the patient should remove the denture and clean it and a topical antifungal medication may be needed. c. the patient requires an antibiotic because it is a bacterial infection d. an antiviral agent is necessary because it is a herpetic infection

B the patient should remove the denture and clean it and a topical antifungal medication may be needed.

The HIV protease inhibitors are predominately metabolized by a. CYP1A2 b. CYP3A4 c. CYP2C9 d. CYP2D6

CYP3A4

Fungal infections are caused by bacteria, true or false

False

HIV is a DNA virus, true or false

False

HSV infection is curable, true or false

False

Herpes simplex virus infections only occur in healthy individuals, true or false

False

Infections caused by herpes simplex virus are transmitted sexually. t or f

False

tetracycline is an acceptable drug for the treatment of herpes infection, true or false

False

Which of the following antiretroviral drugs may cause numbness in the mouth? a. fosamprenavir b. ritonavir c. indinavir d. saquinavir

Fosamprenavir

Recurrent herpes simplex virus infection is caused by a. HSV-1 b. HSV-2 c. HIV d. bacteria

HSV-1

HAART refers to ____- active antiretroviral therapy

Highly

Which of the following drugs is a HIV protease inhibitor a. indinavir (Crixivan) b. nevirapine (Viramune) c. zalcitabine (ddc) Ziagen d. delavirdine (Rescriptor)

Indinavir

__________ are used int eh treatment of Hep C

Interferons

systemic antifungal agents are metabolized via a. kidneys b. lung c. P450 liver enzyme d. acetaminophen with codeine e. broad-spectrum antibiotics

P450 liver enzyme

Which of the following antiherpetic drugs is recommended for herpes labialis? a. ganciclovir b. famciclovir c. valacyclovir d. penciclovir

Penciclovir

which of the following drugs is contraindicated for treating herpes labialis? a. penicillin b. docosanol c. penciclovir d. acyclovir

Penicillin

Hep C is an infection of the liver caused by a single-stranded _______ virus

RNA

Which of the following condition may occur if aspirin is administered to children with viral infections? a. meningitis b. Reye's syndrome c. stroke d. hypertension

Reye's syndrome

Nystatin oral suspension is used to treat thrush, t or f

True

the brand name for didansoine (ddl) is _______

Videx

From the list provided, select the periodontal conditions that may occur in HIV infected individuals a. necrotizing ulcerative gingivitis b. necrotizing ulcerative periodontitis c. linear gingival erythema d. localized aggressive periodontitis

a, b, and c.

which of the following is the brand name of docosanol? a. zovirax b. abreva c. valtrex d. nystatin

abreva

which of the following medications is recommeded in nonimmunocompromised individuals with herpes labialis? a. acyclovir cream b. acyclovir tablets c. nystatin cream d. nystatin tablets

acyclovir cream

all of the following are treatment options for oropharyngeal candidiasis except one a. nystatin suspension b. nystatin vaginal tablets c. clotrimazole troches d. acyclovir tablets

acyclovir tablets

which of the following medications is recommended in immonocompromised individuals with herpes labialis a. acyclovir tablets b. acyclovir cream c. nystatin cream d. nystatin tablets

acyclovir tablets

which of the following is true about ketoconazole a. used in the treatment of oropharyngeal candidiasis b. can effect warfarin levels c. is available in tablets d. all of the above

all of the above

All of the following are regions where recurrent herpes lesions appear except one a. hard palate b. keratinized gingiva c. alveolar mucosa d. tongue

alveolar mucosa

all of the following are opportunistic infections except which one a. angular cheilitis b. herpes simplex virus c. Kaposi's sarcoma d. arthritis

angular cheilitis

___________ can be used in the treatment of herpes infections

antibiotics

All of the following are stimuli for the development of HSV-1 except which one? a. sunlight b. fever c. surgery d. apples

apples

antiviral drugs should be applied a. at the first symptom of a cold sore b. at the end of the itching phase c. when the ulcers become crusty d. when the ulcers disappear

at the first symptoms of a cold sore

what is the major ingredient in anbesol? a. lidocaine b. camphor c. benzocaine d. benzyl alcohol

benzocaine

Herpes simplex virus I causes oral herpes. There is cross-infection where both HSV-1 and HSV-2 are transmitted by intimate contact

both statements are true

which of the following pathogens is primarily implicated in oral fungal infections? a. candida albicans b. streptococcus mutans c. clostridium difficule d. actinobacillus actinomycetemcomitans

candida albicans

which of the following oral conditions is usually seen under a denture in a patient who does not regularly clean the denture and wears it without removing it at night? a. angular cheilosis b aphthous ulcer c. herpes d. candidaisis

candidaisis

Which of teh following drugs when taken concurrently with a HIG protease inhibitor may cause increased levels? a. ciarithromycin (Biaxen) b. acetominophen (tylenol) c. orange juice d. cocaine

ciarithromycin

which of the following drugs should not be taken together with ritonavir a. clarithromycin b. morphine c. acetaminophen d. aspirin

clarithromycin

another antifungal agent used for angular chelosis and chronic atrophic candidiasis (denture sore mouth)

clotrimazole

antifungal agent used for angular chelosis and chronic atrophic candidiasis (denture sore mouth)

clotrimazole

Which of the following agents is not recommended in patients with a high caries index a. clotrimazole troche b. nystatin cream c. nystatin vaginal d. fluconazole tablets

clotrimazole troche (contain sugar)

from the list provided, select the drugs which are used in the treatment of candida albicans infection. a. clotrimazole (Mycelex) b. acyclovir (Zovirax) c. ketoconazole (Nizoral) d. fluconazole (Diflucan)

clotrimazole, ketoconazole diflucan

another name for herpes labialis is __________ sore

cold

From the list provided select the drugs that can cause oral candidiasis. a. corticosteroid inhaler b. chlorhexidine mouthrinse c. listerine mouthrinse d. acetaminophen with codeine e. broad-spectrum antibiotics

corticosteroid inhaler and broad-spectrum antibiotics

which of the following drugs is a nucleoside reverse transcriptase inhibitor a. indinavir (crixivan) b. atazanavir (reyataz) c. nevirapine (viramune) d. didansoine (ddl) -- (videx)

didansoine (ddl) --(videx)

which of the following antiviral agents is available over-the-counter for treating herpes labialis a. valacyclovir b. docosanol c. penciclovir d. acyclovir

docosanol

which of the following antivirals is available OTC a. acyclovir b. famciclovir c. valacyclovir d. docosanol

docosanol (abreva)

which of the following drugs interacts with systemic flucanazole (diflulcan) a. erythromycin b. penicillin c. acetominophen d. ibuprophen

erythromycin

All HIV infected patients have periodontal disease, t or f

false

Antibiotics are useful in the treatment of primary herpes, true or false

false

Antiretroviral drugs do not cause any oral adverse effects, true or false

false

It is easier to diagnose primary herpes infection in the adult than in the infant. t or f

false

herpes lesions are usually not painful, true or false

false

recurrent herpes simplex virus infection occurs in individuals for the first time, true or false

false

topical antifungal therapy has ______ effects and lower cost to the patient than systemic agents

fewer

which of the following agents is best for severe oropharyngeal candidiasis when topical therapy is inadequate? a griseovulvin b. fluconazole c. clotrimazole d. nystatin

fluconazole

antifungal agent used for severe oropharyngeal candidiasis

fluconazole (diflucan)

Which of the following drugs is recommended for severe oropharyngeal candidiasis in AIDS patient a. nystatin oral suspension b. nystatin vaginal suppositories c. clotrimazole troche d. fluconazole tablets

fluconazole tablets

which of the following is teh cause of angular cheilitis a. viral b. bacterial c. fungal d. vitamin C deficiency

fungal

herpes virus type 2 primarily causes __________ disease

genital

Recurrent herpes simplex virus infection in the mouth is referred to as a. angular chelitis b. migratory glossitis c. herpes labialis d. aphthous ulcer

herpes labialis

increased incidence of oral fungal infections with more ________ patients

immunocomprimised

Reactivation of herpes virus is common in _______ patients

immunocompromised

A patient with HIV/AIDS presents to the dental clinic and is taking many drugs. His chief complaint isa metallic taste in the mouth. Which of the following antiretroviral drugs may cause the problem a. fosamprenavir b. atazanavir c. amprevavir d. indinavir

indinavir

which of the following antiretroviral drugs can cause a metallic taste in the mouth a. indinavir (crixivan) b. atazanavir (reyataz) c. nevirapine (viramune) d. delavirdine (rescriptor)

indinavir (crixivan)

Nystatin is available in the following dosage forms including cream, powder, ointment, oral suspension, vaginal suppositories, and __________

lozenges

Indinavir (Crixivan) causes a ________ taste in the mouth

metallic

dental clinicians are usually most concerned and are involved in the _______ mycoses of the mouth

mucocutaneous

hsv-1 lesions appear on the oral __________

mucosa

candida species is part of the ______ flora of an individual

normal

which of the following is the treatment of choice in the therapy of oral candidiasis a. nystatin suspension b. ketoconazole tablets c. fluconazole tablets d. miconazole ointment

nystatin suspension

topical therapy for oral candidiasis is with _______ oral suspension or _____ troches

nystatin, clotrimazole

In which of the following dosages is acyclovir prescribed for herpes labialis? a. 200 mg q 4h B. 300 mg q id c. ointment 5% q 3 h 3 7 days d. ointment 10% 6times/day 3 10 days

ointment 5% q 3 h 3 7 days

all of the following are factors involved in the development of superficial fungal infections of the oral mucosa except a. broad-spectrum antibiotics b. ill-fitting dentures c. immunocompromised patients d. open margin on a crown

open margin on a crown

The majority of HIV infected patients are taking medications for the disease as well as for _____ infections

opportunistic

which of the following products is an OTC topical anesthetic that can be applied to herpes lesions? a. orabase with hydrocortisone b. orabase with benzocaine c. bioflavonoids d. acidophilus

orabase with benzocaine

Herpes virus type 1 primarily causes ____________ disease

oropharyngeal

HEP C is transmitted primarly ____ through blood and blood products

parenterally

What of the following terms describes the first exposure to herpes virus? a. primary herpetic gingivostomatitis b. recurrent herpes simplex infection c. herpes labialis d. angular chelitis

primary herpetic gingivostomatitis

Skin _____ is a common adverse effect of antiretroviral drugs

rash

medications can only reduce the ___________ of herpes but not cure it

recurrence

Which of the following antiretroviral drugs may cause taste impairment a. enfuvirtide b. nelfinavir c. ritonavir d. saquinavir

ritonavir

HSV-1 is transmitted by contact with ____________

saliva

which of the following drugs should not be taken concurrently with didansoine a. codeine b. metronidazole c. tetracycline d. aspirin

tetracycline

Which of the following terms is used for acute pseudomembranous candidiasis a. esophagitis b. thrush c. vaginitis d. cryptococcosis

thrush

___________ antifungals are usually used in the treatment of fungal infections not involving the oropharyngeal area

topical

Antifungal drugs should be used about ____ days after oral lesions appear

two

herpes labialis is a herpes simples ___________viral infection

type 1

herpes labialis lesions appear as

vesivles or ulcers

which of the following diagnostic techniques is used for oral candidiasis? a. when the lesions are wiped with gauze the plaques do not come off b. when the lesions are wiped with gauze the plaques do come off c. remove some of the lesion and send to the lab. d. remove some of the lesion and apply iodine to it.

when the lesions are wiped with gauze the plaques do come off

Oral candidiasis clincially presents as creamy, _____ plaques on the tongue and buccal mucosa

white

Which of the following drugs may cause stomatitis a. zidovudine b. zalcitabine c. delvirdine d. efavirenz

zalcitabine