Psych 4035 Chapter 14

Electrical stimulation of the amygdala would likely result in

a strong fear response

An increased risk of suicide when first taking an antidepressant drug may be due to

activation of inhibitory 5-HT1A receptors.

The adrenal gland releases cortisol after the pituitary gland releases

adrenocorticotropic hormone.

Deciding not to go to a party because of a belief that those at the party will laugh about you or that you may embarrass yourself is an example of

agoraphobia

The benzodiazepine binding site is located on

alpha subunit of the GABAA receptor.

A quick decision on how to respond to a fear stimulus is made in the

amaydala

Increased activity in the _____________ is associated with fear and anxiety

amygdala

Which of the following brain regions might be targeted for modulation in a treatment to reduce fear and anxiety?

amygdala, thalamus

The first-line treatments for anxiety disorders are

antidepressants

If someone is afraid to a give a presentation because he thinks the audience will not like his ideas, this is an example of...

anxiety

The following indicate that barbiturates have abuse potential except

barbiturates reduce stress, thereby serving as negative reinforcers.

Which of the following are reasons for preferring benzodiazepines over barbiturates?

benzodiazepines have a larger therapeutic index, benzodiazepines produce therapeutic effects at doses that have fewer side effects

The first marketed benzodiazepine drug was

chlordiazepoxide.

High levels of cortisol can cause

damage to the hippocampus

Which of the following would be preferred for the treatment of OCD?

fluvoxamine

Accidental overdose with barbiturates may occur due to

forgetting taking the medication earlier.

Alarm is the first stage in

general adaptation syndrome

If a person who is known as someone who worries about everything and generally upset from these worries likely has...

generalized anxiety disorder

Sonya worries about her grades, her future job, losing family members, and nuclear war on a nearly daily basis

generalized anxiety disorder

A barbiturate that is only effective for 30 minutes would be classified as...

ultrashort-acting barbiturate

A drug that might counteract the effects of a barbiturate would likely

serve as an antagonist for GABAA receptors

Chester cannot register for any classes that involve presenting material in front of the class due to extreme fear of public speaking and his concern that he will be ridiculed by audience members

social anxiety disorder

Which of the following might be expected to reduce problems associated with chronic stress?

inhibitor of CRF, inhibitor of ACTH

If alcohol were consumed after taking a barbiturate

it would strengthen the barbiturate effects

Which of the following are reasons for high risk of overdose with barbiturates?

low therapeutic index, tolerance to anxiolytic but not respiratory depressive effects

All of the following disorders involving anxiety are at least partly mediated by amygdala except

obsessive compulsive disorder

Jerome excessively washes his hands (15-20 times per instance) to reduce stress related to concerns about germs

obsessive compulsive disorder

Buspirone is an anxiolytic drug that acts by

partial agonism of 5-HT1A receptors

Benzodiazepines act as ________________ for GABAA receptors.

positive modulators

After experiencing an assault, Christian reacts to loud noises with a high heart rate and blood pressure and rapid breathing.

post traumatic stress disorder

An immediate decline in being afraid after realizing that a loud noise you heard is not a threat is due to a signal produced by the

prefrontal cortex

An antagonist of 5-HT1A receptors would most likely do which of the following?

reduce the effectiveness of buspirone

During general adaptation syndrome, a sustained level of physiological arousal characterizes the __________ stage.

resistance

Chronic use of barbiturates produces tolerance for anxiolytic effects but not for their

respiratory depression effects