RENAL EXAM THEORY V Nursing

Acute glomerulonephritis

(AGN): immune disease after strept infection. Decreases GFR=excessive acculmulation of water and retention of sodium, onset appears after latent period of about 10 days. s/s: oliguria, edema, *hematuria "tea-colored"* mild HTN, lethargy, proteinuria, loss of appetite. Rx: none, spontaneous recovery, supportive-diet low in sodium, protein, K. Nursing: montor fluid, edema, rest periods. AGN is an inflammatory disease of both kidneys that usually affects children between the ages of 2 and 12. It is an inflammation of the glomeruli that typically follows a streptococcal infection of the skin or throat, or an autoimmune condition. Kidney symptoms usually begin two to three weeks after the initial infection. AGN is not contagious.

Oliguric phase of aki assessment findings

(oliguria may not occur in all patients) -duration of oliguria is 8-15 days; longer the duration, the less chance of recovery. -sudden decrease in urine output <400 mL/day -signs of excess fluid volume: (htn, edema, pleural effusion, dysrythmia, heart failure, pulmonary edema.) -signs of uremia (anorexia, nausea, vomiting, and pruritus) -signs of metabolic acidosis (Kussmaul's respirations). -neurologic changes (tingling of extremities, drowsiness progressing to disorientation, and then coma) -signs of pericarditis (friction rub, chest pain with inspiration, and low-grade fever)

nephrotic syndrome.

-A condition of increased glomerular permeability -results in massive protein loss -often linked genetriclaly or r/t immune/inflammatory process -caused by chronic glomerulonephritis, diabetes mellitus with glomerulosclerosis, amyloidosis, lupus, mutliple myeloma and renal vein thrombosis. -major manifestation is edema -hallmark is albuminuria exceedig 3/5g/day

homeostasis of water through the kidneys

-ADH is primarily responsible for the reabsorption of water by the kidneys -ADH is produced by the hypothalamus and secreted from the posterior lobe of the pituitary gland -secretion of ADH is stimulated by dehydration or high sodium intake and by a decrease in blood volume. -ADH makes the distal convoluted tubules and collecting duct permeable to water -water is drawn out of the tubules by osmosis and returns to the blood; concentrated urine remains in the tubule to be excreted -when ADH is lacking, the client develops diabetes insipidus

complications of dialysis

-ASHD -Disturbances of lipids worsened by dalysis -anemia and fatigue -gastric ulcers -renal osetodystrophy -sleep problems -hypotension -muscle cramps -dysrhthmias -dialysis equilibrium form cerebral fluid shift

Complications of dialysis

-ASHD -disturbances of lipids worsened by dialysis -anemia and fatigue -gastric ulcers -renal osteodystrophy -sleep problems -hypotension -muscle cramps -dysrhythmias -dialysis equilibrium form cerebral fluid shifts.

Homeostasis of acidity (pH)

-Blood pH is controlled by maintaining the concentration of buffer systems -carbonic acid and sodium bicarbonate form the most important buffers for neutralizing acids in the plasma. -the concentration of carbonic acid is controlled by thee respiratory system -the concentration of sodium bicarbonate is controlled by the kidneys. -normal arterial pH is 7.35-7.45, maintained by keeping the ratio of concentrations of sodium bicarbonate to carbon dioxide constant at 20:1 -strong acids are neutralized by sodium bicarbonate to produce carbonic acid and the sodium salts of the strong acid; this process quickly restores the ratio adn thus blood pH. -the carbonic acid dissociates into carbon dioxide and water; because the concentration of carbon dioxide is maintained at a constant level by the respiratory system, the excess carbonic acid is rapidly excreted. -Sodium combined with the strong acid is actively reabsorbed in the distal convoluted tubules in exchange for hydrogen or potassium ions. the strong acid is neutralized by ammonia and is excreted as ammonia or potassium salts.

determination of Blood Urea Nitrogen

-Bun levels indicate the extent of renal clearance of urea nitrogenous waste products -an elevation does not always mean that renal disease is present -Some factors that can elevate the BUN level include dehydration poor renal perfusion, intake of a high-protein diet, infection, stress, corticosteroid use, gastrointestinal GI bleeding, and factors that cause muscle breakdown

Lab profile of ARF

-Elevated BUN creatinine -Sodium retention but may be deceptive due to water retention -Potassium increased -phosphorus increased -calcium decreased -H&H decreased -Sp. Gravity decreased and fixed

Cardiovascular manifestations of Renal failure

-Every body system is affected -hypertension (RAAS), heart failure, pumonary edema, pericarditis, MI

Gerontologic Considerations

-GFR decreases following 40 years with a yearly decline of about 1 mL/min -renal reserve declines -multiple medications can result in toxic metabolites -diminished osmotic stimulation of thirst -incomplete emptying of bladder -urinary incontinence.

complications of glomerular nephritis

-Hypertensive encephalopathy -heat failure -Rapid decline in renal function can occur to ESRD

Neurological manifestations of renal failure

-LOC changes, confusion, seizures, agitation, neuropathies, RLS

Acute renal failure intrarenal actual parenchymal damage

-Prolonged renal ischemia form myoglobinuria (rhabdo, trauma, burns), hemglobinuria (transfusion reaction, hemolytic anemia) -nephrotoxic agents like amnioglycosides, radiopaque contrast, heavy metals, solvents, NSAIDs, ACEIs, acute glomerulonephritis.

Pharmacologic management of urinary incontinence

-TCAs -anticholinergics- sudafed, detrol ditropan -estrogen in women

Homeostasis of sodium

-When sodium increases, extra water is retained to preserve osmotic pressure -increase in sodium and water produces an increase in blood volume and BP -when BP increases, glomerular filtration increases, and extra water and sodium are lost; blood volume is reduced, returning the BP to normal. -reabsorption of sodium in the distal convoluted tubules is controlled by the renin-angiotensin system -Renin, an enzyme is released from the nephron when the BP or fluid concentration in the distal convoluted tubule is low -renin catalyzes the splitting of angiotensin I from angiotensinogen; angiotensin I converts to angiotensin II as blood flows through the lung. Angiotensin II, a potent Vocontrictor, stimulates the secretion of aldosterone. Aldosterone, stimulates the distal convoluted tubules to reabsorb sodium and secrete potassium -the additional sodium increases water reabsorption and increases blood volume and BP, returning the BP to normal; the stimulus for the secretion of renin then is removed.

indications for Dialysis (AEIOU)

-acidosis -electrolytes -ingestions -overload -uremia

treatment of urolithiasis

-analgesia -avoid nsaids if having lithotripsy (will affect platelets) -hydration -urine straining -lithotripsy (monitor ECG and sedate patient) -minimally invasive surgical procedures (MIS) such as stenting, nephrolithiotomy. -ABX

hematologic manifestations of renal failure

-anemia, thrombocytopenia

Golmerular Disease

-anitgen-antibody complexes form in blood and become trapped in glomerular capillaries -induce an inflammatory response -manifested by proteinuria, hematuria, decreased GFR and alteration in excretion of sodium -acute and chronic glomerulonephritis -nephrotic syndrome

pathophys of acute glomerulonephritis

-antigen-antibody complexes are produced in response to group A beta-hemolytic streptococcus infection -entrapment and collection of antigen-antibody complexes occurs in the glomerular capillary membranes -inflammatory damage results, impeding glomerular function -ummune complement may further damage the glomerular membrane

Access

-arteriovenous fistula (AVF) -graft -tunneled catheter

Post-op kidney transpant

-assess for s/s of rejection such as oliguria, edema, fever, increasing blood. -Monitor creatinine level, in those on cyclosporine, may be the only s/s -monitor WBC -monitor urinary output, may need hemodialysis temporarily (2-3 weeks may initially have ATN)

Access with CKD

-avoid PICC/midlines in CKD stage 4-5 -try to preserve access -try for feet or EJ -but if needed order a midline.

Nutritional therapy for ARF

-azotemia and uremia are directly related to the rate of protein breakdown. -dietary proteins are individualized to each patient. In a catabolic state and if insufficient intake, patient may lose up to 0.5-1 pounds daily. encourage high CHO. Protein needs for not dialysis patients need 0.6g/kg of body weight . -dialysis patient's need 1-1.5 g/kg protein -fluid restriction= urine volume pluse 500 mL

The nurse observes a client with kidney failure has increased rate and depth of breathing. Which laboratory parameter does the nurse suspect is associated with this client's condition? -Potassium 8 mEq/L -Hemoglobin 10 g/dL -Phosphorous 7 mg/dL -Bicarbonate 1 mEq/L

-bicarbonate 15 mEq/L an increased rate and depth of breathing is called kussmaul respiration and occurs due to metabolic acidosis in clients with kidney disease. The serum bicarbonate level decreases in metabolic acidosis. normal range of serum bicarbonate is 20-30.

Calciphylaxis

-calcifation of the small vessels of the dermis and subcutaneous tissues occurs. This leads to vessel thrombosis, tissue infarction and skin necrosis -1-4% of dialysis patients -risk factors include hyperparathyroidism, and elevated calcium-phosphate product (>70 mg/dl), DM, female sex, obesity, warfarin use, and protein C or S deficiency. -1 year survival after dx of caliphylaxis is about 50%. -very painfulviolaceous reticulated plaques that are well defined and deep. develop into deep non-healing ulcers that can become gangrenous. Sepsis is the most common cause of mortality.

Creatinine Clearance .

-calculated measure of glomerular filtration rate. Is best indicator of overall kidney function. -Based on 24 hour urine collection -midway will obtain serum creatinine. Serum creatinine levels vary with age, gender and body muscle mass. -calculate: (volume of urine X urine creatinine) divided by serume creatinine.

Dialysis Disequilibrium Syndrome

-caused by rapid decrease in fluid volume and blood urea nitrogen levels during HD -Change in urea levels can cause cerebral edema and increased ICP -Neurologic complications include: HA, vomiting, restlessness, decreased LOC, Seizures, coma or death -can be prevented by starting HD for short periods and low blood flows.

Dialysis Disequilibrium syndrome

-caused by rapid decrease in fluid volume and blood urea nitrogen levels during HD -Change in urea levels can cause cerebral edema and increased ICP -neurologic complicatoins include: HA, vomiting, restlessness, decreased LOC, seizures, coma or death. -can be prevented by starting HD for short periods and low blood flows.

Uremia

-collection of nitrogenous wastes normally excreted by the kidneys. S/s include: HA, seizures, coma, dry skin, rapid pulse, elevated BP, scanty urine, labored breathing.

Common Admissions

-complications of missed HD *SOB from fluid overload *HTN crisis *hyperkalemia -Line infections -access issues

determination of serum creatinine levels

-creatinine levels reflects the glomerular filtration rate -kidney disease is the only pathological condition that increases the serum creatinine level -serum creatinine level increases only when at least 50% of renal function is lost

Factors contributing to urinary incontinence in the elderly

-diuretics -CNS depressants which affect LOC -CVAs -Parkinson's -Depression and altered self-esteem -inability to ambulate safely -assistance products cost prohibitive for patient -UTI

Glomerulus

-each nephron contains tufts of capillaries which filter large plasma proteins and blood cells -Blood flows into the glomerular capillaries from the afferent arteriole and flows out of the glomerular capillaries into the efferent arteriole.

labs for oliguric phase of AKI

-elevated BUn and serum creatinine -decreased urine Sp. G. (prerenal causes), or normal (intrarenal causes) -deceased GFR and creatinine clearance -hypokalemia -normal or decreased serum sodium -Hypervolemia -hypoalcemia -hyperphosphatemia

diagnosis of urolithiasis

-evaluate for bladder obstruction -UA will reveal RBCs, odor, tubidity, WBCs -MRI, KUB, CT -Noncontrast helical CT has highest sensitivity -IV urography will show obstruction

Labs in ESRD

-get labs before or 4 hours after hemodialysis -only the h/h is accurate -floor RNs can't use HD lines -can ask to have cultures drawn at HD from the line.

What would cause increased creatinine levels

-gigantism -acromegaly -renal disease -rhabdomyolysis -congestive heart failure -dehydration -shock -hyperparathyroidism

clinical manifestations of acute glomerular nephritis

-hematuria -Edema -Azotemia-accumulation o nitrogenous wastes -Urine appearance may be cola colored -hypertension -hypoalbuminemia -hyperlipidemia -rising BUN and creatinine

Arteriovenous Fistula

-highest patency -lowest risk of infection -low risk of thrombus -maturation time 3-4 mo -steal syndrome (poor blood supply to the rest of the limb) -aneurysm formation

Risk factors for renal or urologic disorders

-htn -DM -Immobilization -Parkinson's disease -SLE -Gout -Sickle cell anemia, multiple myeloma -BPH -pregnancy -SCI

Tunneled Catheter

-immediate use -bridge to AVF/AVG -Poor flow (decreased HD efficiency) -high infection risk -venous stenosis -thrombosis

Homeostasis of potassium

-increase in the serum potassium level stimulate the secretion of aldosterone -Aldosterone stimulates the distal convoluted tubules to secrete potassium; this action returns the serum potassium concentration to normal.

renal medulla

-inner region, which contains the renal pyramids and renal tubules. -together, the renal cortex, pyramids, and medulla constitute the parenchyma.

Causes of acute renal failure

-intrarenal actual parenchymal damage -Prerenal 60-70% of cases -Postrenal

Nephrotic syndrome

-is not a specific glomerular disease -is a syndrome with a cluster of findings that include: Marked increase in protein in urine (especially albumin), Hypoalbuminemia, edema, high serum cholesterol and LDL.

what would cause decreased bun levels

-liver failure -overhydration -inadequate protein intake -pregnancy

Functions of kidneys

-maintain acid-base balance -excrete end products of body metabolism -control fluid and electrolyte balance -excrete bacterial toxins, water-soluble medications, and medication metabolites -Secrete renin to regulate the blood pressure and erythropoietin to stimulate the bone marrow to produce red blood cells -Synthesize vitamin D for calcium absorption and regulation of the parathyroid hormones

Management of ARF

-objectives: restore normal chemical balance and prevent complications until restoration of renal function. -identify and treat underlying cause -maintain fluid balance- wts, serial CVP readings, BP, strict I&O. -May give Mannitol, Lasix or Edecrin -May need temporary dialysis -if prerenal, fluid challenges and diuretics to enhance renal blood flow -Oliguric renal failure, POSSIBLY (not supported) low dose dopamine. Calcium channel blockers may be used to prevent influx of calcium into kidney cells, maintains cell integrity and increase GFR -Hyperkalemia- closely monitor electrolytes -Kayexalate/Sorbitol- May need flexiseal -IV dextrose, insulin and calcium may help shift K+ -Monitor ABGs and acid-base balance -monitor phosphate levels.

Diabetic neuropathy

-occurs in both types of DM -severity of diabetic renal disease is related to extent, duration and effects of atherosclerosis, htn, and neuropathy -microvascular complication of diabetes -first manifestation is persistent albuminuria -diabetic patients are always considered to be at risk for renal failure -avoid nephrotoxic agents and dehydration

Diabetic Nephropathy

-occurs in types 1 and 3 -Severity of diabetic renal disease is related to extent, duration and effects of atherosclerosis, htn and neuropathy.

kidney anatomy

-one kidney is attached to the left abdominal wall at the level of the last thoracic and first 3 lumbar vertebrae, the other is on the right -the kidneys are enclosed in the renal capsule

Prerenal AKI

-outside the kidney -caused by intravascular volume depletion such as with blood loss associated with trauma or surger, dehydration, decreased cardiac output (cardiogenic shock), decreased peripheral vascular resistance, decreased renovascular blood flow, and prerenal infection or obstruction.

Peritoneal Dialysis

-peritoneal membrane = partially permeable membrane -dextrose dialysate -diffusion and osmosis until equilibrium -3-10 dwells per night with 2-2.5 L per dwell.

key features of ARF

-prerenal-hypotension, tachycardia, decreased CO, decreased urinary output, lethargy -intrarenal and postrenal- oliguria or anuria, hypertension, tachycardia, SOB, orthopnea, n/v, generalized edema and weight gain. lethargy, confusion.

Chronic Renal Failure (end-stage renal disease)

-progressive, irreversible deterioration in renal function -Causation: #1 diabetes mellitus, hypertension, glomerulonephritis, pyelonephritis, polycystic kidney disease, vascular disorders

functions of the Kidney

-regulation of water excretion -regulation of electrolyte function -regulation of acid-base balance-retain HCO3-and excrete acid in Urine -regulation of blood pressure--RAAS -Regulation of RBC's -vitamin D synthesis -secretion of prostaglandin E and prostacyclin which cause vasodilation, important in maintain renal blood flow -Excretion of waste products-body's main excretory organ. urea, creatinine, phosphatase, uric acid and sulfates. Durg metabolites

Treatment of nephrotic syndrome

-renal biopsy to determine specific cuase -steroids -immunosuppressive agents -ACEIs can decrease proteinuria -Cholesterol lowering agents -Heparin to reduce coagulability -Limit sodium intake

what would cause decreased levels of creatinine clearance

-renal disease -congestive heart failure -obstruction within kidney -dehydration

Acute glomerulonephritis

-renal disease in which the glomeruli become inflamed -usually associated with a postinfectious state, commonly a streptococcal infection of the respiratory tract or, less commonly, a skin infection such as impetigo -95% of children and 70% of adults recover -elderly patients may progress to chronic renal failure

what causes increased BUN levels

-renal failure -congestive heart fialure -myocardial infarction -kidney disease -shock -dehydration -excessive protein intake -diabetes mellitus (DM) -GI bleed -urinary tract obstruction

hormones that influence renal function

-renin- raises BP -Bradykinins- increase blood flow and vascular permeability -erythropoietin -ADH -Aldosterone-promotes sodium reabsorption and potassium excretion -natriuretic hormones- released from the cardiac atria and brain.

Complications of peritoneal dialysis

-respiratory difficulties -hypotension -infection: peritonitis; see cloud or opaque dialysate outflow (effluent). fever, abdominal tenderness, pain malaise, N&V. -hypo-albuminemia -bowel perforation -bladder perforation -catheter may get clogged.

Dermal manifestations of renal failure

-severe pruritus, uremic frost (urea crystals)

A client is diagnosed as having invasive cancer of the bladder, and brachytherapy is scheduled. What should the nurse expect the client to demonstrate that indicates success of this therapy? -decrease in urine output -increase in pulse strength -shrinkage of the tumor on scanning -increase in the quantity of WBC

-shrinkage of the tumor on scanning Brachytherapy, in which isotope seeds are implanted in the tumor, interferes with cell multiplication, which should control the growth and metastasis of cancerous tumors.

Stages of of renal failure

-stage 1: kidney damage with normal or increased GFR (>90) -stage 2: mild reduction in GFR (60-89) -stage 3: moderate reduction in GFR (30-59) -stage 4: severe reduction in GFR (15-29) -stage 5: kidney failure (<15)

Bladder

-the bladder detrusor muscle, composed of smooth muscle, distends during bladder filing and contracts during bladder emptying -the ureterovesical sphincter prevents reflux of urine from the bladder to the ureter -the total bladder capacity is 1:; normal adult urine output is 1500 mL/day.

renal capsule vs renal cortex

-the kidneys are enclosed in the renal capsule -the renal cortex is the outer layer of the renal capsule, which contains blood-filtering mechanisms (glomeruli).

nephrons

-the nephrons are the functional units of the kideny -located within the parenchyma -composed of glomerulus and tubules -selectively secretes and reabsorbs ions and filtrates, including fluid, wastes, electrolytes, acids, and bases.

Creatinine (CR)

0.7-1.4 mg/dL indications- identify muscular disorders and renal disease -creatinine is a byproduct of creatine metabolism and it is excreted by the kidneys. Creatinine is created in proportion to muscle mass and usually stays stable.

Which intervention would be most beneficial in preventing a catheter-associated urinary tract infection in a postoperative client? 1. Pouring warm water over the perineum 2. Ensuring the patency of the catheter 3. Removing the catheter within 24 hours 4. Cleaning the catheter insertion site

3. removing the catheter within 24 hours. Infections can be prevented by removing the catheter within 24 hours, if the client does not need it.

Creatinine Clearance

85 to 125 mL/min used to determine: kidney damage in renal disease, glomerular function, effectiveness of treatment -Creatinine is a byproduct of creatine metabolism and is excreted in the kineys. Creatinine is created in proportion to muscle mass and usually stays stable. urine and blood levels are compared to determine creatinine clearance from the blood. any disease that affects the kidneys ability to clear waste products will increase blood creatinine levels and decrease creatinine clearance levels.

Angiotensin

A normal blood protein produced by the liver, angiotensin is converted to angiotensim I by renin (secreted by kidney when blood pressur falls). Angiotensin I si further onverted to angiotensim II by ACE (angiotensin converting enzyme). Angiotensin II is a powerful systemic vasocontrictor ans stimulator of aldosterone relase, both of which result in an increase in blood pressure.

Diagnostic tests used to measure kidney size of a client w/ kidney dysfunction? Select all that apply.a. cystoscopyb. cystographyc. radiographyd. cystourethrographye. computed tomography (CT)

A radiography and a computed tomography (CT) are diagnostic tests used to measure kidney size in clients with kidney dysfunction. A cystoscopy is used to identify abnormalities of the bladder wall in clients with kidney dysfunction. A cystography and a cystourethrography are used to examine the structure of the urethra and to detect backward flow of urine.

Medications in ESRD

ABX- renally dose, loading dose, then maintenance No lovenox dvt PPX, use heparin no morphine - hepatic metabolism but active metabolites. limit other opioids (dilaudid: hepatic metabolism but metabolites cause neuroexcitiation) constipation/GERD: avoid magnesium/phosphate containing agents

On assessment, the nurse notes that a client with acute kidney injury (AKI) has developed fine crackles in the lung bases bilaterally. what should the nurse do?

AKI is the sudden loss of kidney function caused by renal cell damage form ischemia or toxic substances. It occurs abruptly and can be reversible. AKI leads to hypoperfusion, cell death, and decompensation in renal function. With this disorder, the nurse should monitor for complications such as fluid overload, ascites, pulmonary edema and heart failure. If fine crackles in the lung bases develop bilaterally, the nurse should notify the health care provider because this could be a sign of one of these complications.

treatment for uric acid stone

allopurinol and alkalinizing the urine. sodium bicarbonate or potassium citrate is helpful

Tests reveal that a client has phosphatic renal calculi. The nurse teaches the client that the diet may include which food item?

apples- low in phosphate, fresh fruit is low in phosphorus. Chocolate contains more phosphate than apples. Rye bread contains more phosphate than apples. Cheese is made with milk, which contains phosphate and should be avoided.

Dialysis

based on principles of diffusion, osmosis, and ultrafiltration

bladder ultrasonography

bladder scan -noninvasive method for measuring the volume of urine in the bladder -may be performed to evaluate frequency, inability to urinate, or amount of residual urine.

steal syndrome

blood entering the limb is drawn into the fistula and returned to the general circulation without entering the limb's capillaries. this results in cold extremities of that limb, cramping pains, and if severe, tissue damage; vasculature that supplies the rest of the limb is poor.

medical management of Renal failure

calcium and phosphorus binders- Calcium carbonate, calcium acetate. -antihypertensives -antiseizures- valium or dilantin -erythropoietin -iron supplements -Diet - CHO and fat, vitamins, restrict protein.

24 hour urine collection

check with lab about specific instruction -instruct the client about the urine collection -at the start time, instruct the client to void and discard that sample. -collect ll urine for the prescribed time (24 hours) -keep the urine specimen on ice or refrigerated and check with the laboratory regarding adding a preservative to the specimen during collection. -at the end of the prescribed time, instruct the client to empty the bladder and add that urine to the collection container.

Which component of the client's nephron acts as a receptor site for the antidiuretic hormone and regulates water balance?

collecting ducts -The collecting ducts regulate water balance and act as a receptor site for antidiuretic hormone. The Bowman's capsule collects glomerular filtrate and funnels it into the tubule. The distal convoluted tubule acts as a site for additional water and electrolyte reabsorption

Which urodynamic study provides information on bladder capacity, bladder pressure, and voiding reflexes? 1-Radiography 2-Renal arteriography 3-Electromyography (EMG) 4-Cystometrography (CMG)

cystometrography -Cystometrography (CMG) is an urodynamic study that provides information on bladder capacity, bladder pressure, and voiding reflexes.

major manifestation of nephrotic syndrome

edema

A client has been diagnosed with anemia. Which decreased hormone level may be the cause?

erythropoietin -Erythropoietin stimulates the production of red blood cells (RBCs) in the bone marrow. Deficiency of erythropoietin causes a decrease in RBCs, thereby resulting in anemia. Bradykinin increases blood flow and vascular permeability. Prostaglandins regulate kidney perfusion. Activated vitamin D promotes the absorption of calcium in the gastrointestinal (GI) tract.

epo

erythropoietin; promotes growth of red blood cells

Creatinine Clearance nclex book

evaluates how well the kidneys remove creatinine from the blood, and is an estimate of GFR -best estimate of the GFR.

hypercalcemia

excessive calcium in the blood

osmosis

exess water is removed. goes form area of higher solute concentration (blood) to lower concentration (dialysate)

A client has a kidney transplant. The nurse should monitor for which assessment findings associated with rejection of the transplant? Select all that apply. -fever -oliguria -jaundice -polydipsia -weight gain

fever, oliguria, and weight gain. -Fever is a characteristic of the systemic inflammatory response to the antigen (transplanted kidney). Oliguria or anuria occurs when the transplanted kidney is rejected and fails to function. Weight gain can occur from fluid retention when the transplanted kidney fails to function or as a result of steroid therapy; this response must be assessed further.

The blood urea nitrogen (BUN)/creatinine ratio of a client is 3. Which condition does the nurse suspect in the client?

fluid volume excess -The normal range of the blood urea nitrogen (BUN)/creatinine ratio is from 6 to 25. A decrease in the BUN/creatinine ratio indicates fluid volume excess. An increase in the BUN/creatinine ratio indicates obstructive uropathy. A decrease in the levels of blood urea nitrogen (BUN) indicates severe hepatic damage. An increase in the levels of blood urea nitrogen (BUN) indicates gastrointestinal (GI) bleeding.

A client is diagnosed with condyloma acuminatum. Which finding in the client supports the diagnosis?

genital warts. -moist, fleshy projectionson the penis

nephrotic syndrome

group of clinical signs and symptoms caused by excessive protein loss in urine

24 hour collection

have patient void first and do not add to collection device. -then start time -follow agencies policy on cooling of urine -Post signs to ensure all urine is collected.

Types of Dialysis

hemodialysis (HD) Continuous Veno-venous hemofiltration (CVVH) Peritoneal dialysis

BUN/Creatinine Ratios

high ratios 20:1 typically indicate low flow to kidneys, i.e. dehydration or CHF. -Low ratios 10:1 can be seen with liver failure patients.

renin

hormone secreted by the kidney; it raises blood pressure by influencing vasoconstriction (narrowing of blood vessels)

Tx for upper UTI

hydration -antiemetics -two week course o abx such as bactrim, cipro, gentamycin w/ or w/o ampicillin, 3rd generation cephalosporin -pregnant women hospitalized for 2-3 days. f/u culture in two weeks

Thiazide treatment for

hypercalciuria stones

A nurse is caring for a client with a diagnosis of chronic kidney failure who has just been told by the primary healthcare provider that hemodialysis is necessary. Which clinical manifestation indicates the need for hemodialysis?

hyperkalemia -Protein breakdown liberates cellular potassium ions, leading to hyperkalemia, which can cause a cardiac dysrhythmia and standstill. The failure of the kidneys to maintain a balance of potassium is one of the main indications for dialysis.

Which test helps to identify fibroids, tumors, and fistulas while performing a reproductive tract examination?

hysterosalpingography -A hysterosalpingogram is an X-ray used to evaluate tubal anatomy and patency and used to identify uterine problems such as fibroids, tumors, and fistulas.

urine osmolality

indication of concentrating ability, changes seen early in disease processes

Urea nitrogen

indicator of renal function. 7-18 mg/dL. measures renal excretion of urea nitrogen, a byproduct of protein metabolism. Is not always elevated with kidney disease. Not best indicator of renal function.

glomerulonephritis

inflammation of the glomeruli within the kidney

Renal biopsy

insertion of needle into the kidney to obtain a sample of tissue for examination done percutaneously. assess- vitals, baseline coag, informed consent, post-procedure- monitor vital signs, especially hypotension and tachy. pressure biopsy site, monitor h/h. strict bed rest, encourage fluids,

stress incontinence

involuntary loss of urine w/ activities that increase intraabdominal pressure.

Formation of stones

involves 3 conditions 1. slow urine flow resulting in supersaturation of the urine with the particular element. 2. Damage to the lining of the urinary tract 3. Decreased inhibitor substances in the urine that would otherwise prevent supersaturation and crystal aggregation

describe the glomerulus

is the initial part of the nephron, which filters blood to make urine

renography

kidney scan -an IV injection of a radioisotope for visual imaging of renal blood flow, glomerular filtration, tubular function, and excretion. -pre-procedure- verify informed consent -post-procedure- encourage fluids, asses allergic reaction, wear gloves for excretion.

neurogenic bladder

lesions of ns leads to urinary incontinence -may be caused by MS, SCI, HNP, spinal tumor, spina bifida, diabetes -assess by checking residuals, I&O, UA, assessing sensory awareness.

BUN extra info

liver must function properly to produce urea nitrogen. BUN levels indicate the extent of renal clearance of this nitrogenous waste product. -may see elevation of BUN with bleeding into tissues or from rapid cell destruction from infection/steroids.

A nurse is caring for a client who had a nephrectomy because of cancer of the kidney. Which factor will influence the client's ability to deep breathe and cough postoperatively?

location of surgical incision

What would cause decreased creatinine levels

loss of muscle mass muscular dystrophy inadequate protein intake pregnancy liver disease

A nurse educates the client about the relationship between the kidneys and blood pressure. Which term should the nurse use to describe the part of the kidney that senses changes in blood pressure?

macula densa- the macula densa is a part of the distal convoluted tubule and consists of cells that sense changes in the volume and pressure of blood calices are cup-like structures, present at the end of each papilla that collect urine.

musculoskeletal clinical manifestations of renal failure

muscle cramps, renal osteodystrophy, bone pain, bone fractures.

GI manifestations of renal failure

n/v, anorexia, uremic fetor (ammonia odor to breath) constipation or diarrhea.

cause tubular secretion of sodium. release from cardiac atria and brain

natriuretic hormones

Damaged glomerular cap. membrane leads to loss of plasma protein (albumin), stimulates synthesis of lipoproteins leading to hyperlipidemia.

nephrotic syndrome

Adrenal Glands

one adrenal gland is on top of each kidney the adrenal glands influence BP and sodium and water retention

The nurse is educating student nurses about the anatomy and physiology of the kidneys. What term does the nurse explain is used for the tip of the pyramid of a kidney?

papilla Pyramids are components of renal medulla, and the tip of each pyramid is called a papilla. A calyx is a structure that collects the urine at the end of each pyramid

The client diagnosed with a fistula between the bowel and urinary bladder reports passing air and bubbles during urination. What does the nurse anticipate the client's condition to be?

pneumaturia -The occurrence of gas along with urination is called pneumaturia and could result from the formation of a fistula between the bowel and urinary bladder.

Which serum laboratory values in a client with urinary problems may indicate the risk of developing muscle weakness and cardiac arrhythmias? Calcium of 9.5 mg/dL (2.375 mmol/L) Potassium of 7.02 mEq/L (7.02 mmol/L) Bicarbonate of 22.8 mEq/L (22.8 mmol/L) Phosphorus of 4.1 mg/dL (1.3243 mmol/L)

potassium of 7.02 mEq/L (7.02 mmol/L) -The normal level of serum potassium is between 3.5-5.0 mEq/L (3.5 and 5.0 mmol/L). Elevated potassium levels greater than 6 mEq/L (mmol/L) can lead to muscle weakness and cardiac arrhythmias. The normal levels of serum phosphorus are between 2.4-4.4 mg/dL (0.78 and 1.42 mmol/L). The normal levels of serum calcium are usually between 8.6-10.2 mg/dL (2.15 and 2.55 mmol/L). The normal level of serum bicarbonate is between 22 and 26 mEq/L or mmol/L. These findings are not associated with the risk of developing muscle weakness and cardiac arrhythmias.

Urolithiasis

presence of calculi in urinary tract -cause pain as they pass

which hormone is crucial in maintaining the implanted egg

progesterone

what is the action of vasopressin?

reabsorbs water into the capillaries. -Vasopressin is also known as an antidiuretic hormone (ADH). It helps in the reabsorption of water into the capillaries. Aldosterone promotes sodium reabsorption. Natriuretic hormones promote tubular secretion of sodium. Erythropoietin stimulates bone marrow to make red blood cells (RBCs).

erythropoietin

released by the kidneys in response to poor blood flow to the kidneys; it stimulates the production of red blood cells.

diffusion

removal of toxins and wastes move form blood to dialysate

Which statement is true regarding the functions of kidney hormones?

renin raises blood pressure because of angiotensin and aldosterone secretion

kidney hormones

renin, bradykinin, and erythropoietin

describe juxtaglomerular cells

secret renin, renin is produced when sensing cells in the macula densa sense changes in blood volume and pressure

reflex incontinence

seen in SCI patients

functional incontinence

seen in alzheimer's

renal disease is the only common pathological condition that increases what serum level

serum creatinine. does not increase until at least 50% of renal function is lost

creatinine clearance

tests clearance of creatinine in one min. Relects GFR

cystoscopy/ biopsy of bladder

the bladder mucosa is examined for inflammation, calculi, or tumors by means of a cystoscope; a sample for biopsy can be obtained -pre-procedure- verify informed consent, withhold fluids and food with biopsy. -post-procedure - increase fluids, monitor I&O, encourage deep breathing to relieve bladder spasm, monitor for clots

To prepare for hemodialysis, a client with end-stage kidney disease is scheduled for surgery, specifically for the creation of an internal arteriovenous fistula in one arm and placement of an external arteriovenous shunt in the other arm. When considering care for these sites, which difference will the nurse consider?

the graft is more subject to hemorrhage, clotting, and infection that the fistula is -The external shunt may come apart with possible hemorrhage; clotting is a potential hazard. Frequent handling increases risk of infection. Blood pressure readings should not be obtained in the extremity that has a shunt or fistula because of the pressure exerted on the circulatory system during the procedure. IVs should not be infused in the extremity with the shunt or the fistula to avoid pressure from the tourniquet and to lessen the chance of phlebitis. The ends of the shunt cannula should be left exposed for rapid reconnection in the event of disruption.

Hemodialysis

the process by which waste products are filtered directly from the patient's blood

Acute Kidney Injury (AKI)

the rapid loss of kidney function from renal cell damage -occurs abruptly but can be reversible. -Leads to cell hyperperfusion, cell death, and decompensation of renal function. -prognosis depends on the cause and the condition of the client -near-normal or normal kidney function may resume gradually.

When assessing a client during peritoneal dialysis, a nurse observes that drainage of the dialysate from the peritoneal cavity has ceased before the required volume has returned. What should the nurse instruct the client to do? -Drink a glass of water -Turn from side to side -Deep breathe and cough -Rotate the catheter periodically

turn from side to side -Turning from side to side will change the position of the catheter, thereby freeing the drainage holes of the tubing, which may be obstructed.

Arteriovenous Graft

type of surgically created vascular access for dialysis by which a piece of biologic, semibiologic, or synthetic graft material connects the patient's artery to a vein -easier to create -Maturation time 3-6 weeks -Poor patency (often requires thrombectomy or angioplasty) -infection -aneurysms -steal syndrome

spastic neurogenic bladder

upper motor neuron lesions

metabolic changes in renal failure

urea and creatinine, sodium, potassium, acid-base, calcium and phosphorus

Tx of neurogenic bladder

urecholine, surgery, intermittent caths, S/P caths

Complications of nephrotic syndrome

-massive proteinuria -hypoalbunemia -Edema -Lipiduria -hyperlididemia -increased coaguation -renal insufficiency

etiology of urolithiasis

-metabolic factors such as hyperuricemia, hyperoxaluria, or hpercalcemia -High dietary calcium not contributive unless metabolic or renal tubular defects exists -immobilization -urinary stasis, dehydration and urinary retention may be causative

Role of the nurse in ARF

-monitor fluid and electrolyte balance -Reduce metabolic demands -Promote pulmonary function -prevent infection -provide skin care -provide support

Kidney transplantation

-more successful if done before dialysis -HLA and ABO compatibility -donor kidney placed in iliac fossa -patient must be free from infection -similar care for patient post-op as any surgery

what would cause increased levels of creatine kinase?

-muscle damage -rhabdomyolysis -muscular dystrophy -heart attack -exercise -kennedy's disease -stroke

Dialysis therapies indications

uremia persistent hyperkalemia uncompensated metabolic acidosis fluid volume excess uremic encephalopathy remove toxic substances

Acute renal failure Post renal

urinary obstruction by calculi, tumors, BPH, blood clots.

What instruction regarding sample collection should the nurse give a client who is ordered a clean-catch urine specimen?

urinate small amount, stop flow, fill half of cup.

A nurse is caring for a client after surgical creation of a conduit diversion (ileal conduit). Which information will the nurse consider when planning care for this client?

urine continuously drains from it

uremia

urine in the blood

Renal function tests

urine osmolality creatinine serum creatinine urea nitrogen

ultrafiltration

water moves from high pressure area to lower pressure. applied by negative pressure, more efficient than just osmosis

therapy for incontinence

weight loss in obese -fluid management -transvaginal or transrectal electrical -inflatable cuff -Vaginal cone retention exercises -Urinary catheterization -scheduled toileting -pelvic muscle exercises

overflow incontinence

when bladder is distended, will have small amount of incontinence

intravenous urography

x-ray, where a radiopaque dye is injected IV to visualized and identify abnormalities in the renal system. pre-procedure-- verify informed consent, assess allergies to iodine, seafood, and radiopaque dyes, positive preg test, asthma, cardiac disease and renal insufficiency.

Postrenal AKI

-Between the kidney and urethral meatus, such as bladder neck obstruction, bladder cancer, calculi, and postrenal infection.

Imaging with CKD

-avoid contrast -if you have to prep (volume expansion: isotonic IVFs (3 cc/kgx1h before & 1cc/kgx 6h after) alkalinization: sodium bicarbonate, acetylcysteine, radiology can give you the protocol)

kidney changes with ESRD

-nephrons hypertrohpy and work harder until 70-80% of renal function is lost. -Nephrons could only compensate by decreasing water reabsorption thus: --hyposthenuria- loss of urine concentrating ability occurs -polyuria- increase urine output -then isosthenuria-fixed osmolality -gradual decline in urinary output

Prostate gland

-the prostate gland surrounds the male urethra -the prostate gland contains a duct that opens into the prostatic portion of the urethra and secretes the alkaline portion of seminal fluid, which protects sperm.

aldosterone

"salt-retaining hormone" which promotes the retention of Na+ by the kidneys. na+ retention promotes water retention, which promotes a higher blood volume and pressure

pulmonary manifestations of renal failure

- crackles, kussmaul, pleuritic pain

nephrolithiasis

- formation of stones in the kidney

Imaging in ESRD

-CT with contrast is ok -MRI with gadolinium is Not

causes of AKI

-prerenal -intrarenal -posrenal

kidney Tubules

-the tubules include the PCT, the loop of henle, and the distal convoluted tubule (DCT) -The PCT receives filtrate form the glomerular capsule and reabsorbs water and electrolytes through active and passive transport. -The descending loop of henle passively reabsorbs water from the filtrate -the ascending loop of henle passively rabsorbs sodium and chloride from the filtrate and helps to maintain osmolality -The DCT actively and passively removes sodium and water -the filtered fluid is converted to urine in the tubules, and then the urine moves to the pelvis of the kidney -the urine flows form the pelvis of the kidneys through the ureters and empties into the bladder.

Bowman's capsule

-thin double-walled capsule that surrounds the glomerulus -fluid and particles from the blood such as electrolytes, glucose, amino acids, and metabolic waste (glomerular filtrate) are filtered through the glomerular membrane into a fluid-filled space in Bowman's capsule (bowman's space) and then enter the proximal convoluted tubule (PCT)

management of glomerular nephritis

-treat s/s such as elevated BP -Check GFR by 24h Urine for creatinine clearance -ANA -Treat streptococcal infection with antibiotics, preferably PCN -Corticosteroids -Immunosuppressants -Limit dietary protein, increase CHO -Restrict sodium -May progress to chronic glomerulonephritis, will treat as in CKD

Bladder cancer tx

-ureterostomy -conduits (to intestine and stoma) -Sigmoidostomies- divert urine to large intestine so no stoma -Ileal reservoir- surgically created pouch

acute renal failure Prerenal

-volume depletion as seen in hemorrhage, renal losses form diuretics, GI losses from vomiting, diarrhea -impaired cardiac output 2ndary to MI, heart failure, dysrhythmias, cardiogenic shock -Vasodilation from sepsis, anaphylaxis, antihypertensive meds.

GFR

-volume of fluid filtered from renal glomerular capillaries into Bowman's capsule per unit of time. -Generally expressed in ml/minute -Normal GFR generally is 125mL/minute

Upper urinary tract infections

-will have fever, chills, leukocytosis, bacteriruria, and pyuria. -CVA tenderness -US or CT to r/o any obstruction -Urine C&S

Oliguric phase of AKI intervention

-with early recognition the client may be treated with fluid challenges (IV bolus of 500 to 1000 mL over 1 hour) -restrict fluid intake; if hypertension is present, daily fluid allowances may be 400 to 1000mL pulse the measured urinary output. -administer meds, such as diuretics, as prescribed to increase renal blood flow and diuresis of retained fluid and electrolytes. 822

intrarenal AKI

-within the parenchyma of the kidney; caused by tubular necrosis, prolonged prerenal ischemia, intratenal infection or obstruction, and nephrotoxicity

Serum Creatinine

0.6-1.3 mg/dL ref range -creatinine is a specific indicator of renal function -increased levels of creatinine indicate a slowing of the glomerular filtration rate. -prior to draw, have Pt avoid excessive exercise for 8 hours and excessive red meat for 24 hours

phases of Acute Renal failure.

1. initiation occurs with the insult 2. Oliguria with urinary output less than 400 ml/24h. Rising potassium, BUN, CR. not responsive to fluid challenges. 3. Diuresis period- gradual increase in urinary output. Beginning recovery. Renal function gradually improves 4. Recovery- may take 3-12 months. May have permanent reduction in functioning of 1%-3%

GFR decrease how much with age

10% every decade normal GFR is 125 by age 65 a person will have 65 mL/min

serum sodium

135-145 ref range -major cation of extracellular fluid -maintains osmotic pressure & acid base balance -assists in transmission of nerve impulses -absorbed in the small iintestine and excreted in urine

Chronic kidney disease and GFR

Stage 1 - GFR 90-130 Stage 2 - GFR 60-90 Stage 3 - GFR 30-60 Stage 4 - GFR 15-30 Stage 5 ESRD - GFR <15

serum potassium

3.5-5.0 mEq/L ref range -major intracellular cation -regulates water balance, electrical conduction in muscle cells, and acid base balance -the body obtains potassium through diet -the kidneys preserve or excrete K. depending on cellular need -K levels are used to evaluate cardiac function, renal function, GI function, & need for IV therapy (clients with elevated WBC & PLT count may have false + K levels.

sequence of events in nephrotic syndrome

Damaged glomerular capillary membrane -loss of plasma proteins -hypoalbuminemia -Decreased oncotic pressure -generalized edema --> RAAS --> sodium retention --> edema

creatine kinase

55-170 U/L -monitors muscle damage -can diagnose acute myocardial infarction, ischemia, muscular dystrophy. -creatine kinase enzyme is found inthe heart and skeletal muscle and to a lesser extent the brain. When damage is done to these types of tissue CK is released into the blood. There are three isoenzymes, and depending on which one is elevated this lab value can help determine timing, location, extent of damage. the theee isoenzymes are CK-MB (cardiac), CK-MM (skeletal), CK-BB (Brain)

Blood Urea Nitrogen (BUN)

7-20 indications: liver problems, renal problems, hydration -status, tumor lysis. -evaluate effects on drugs. -monitor effectiveness of hemodialysis -Blood Urea nitrogen measures the amount of urea in the blood. When protein is broken down ammonia is formed. Ammonia is converted to urea in the liver and eventually excreted in the kidneys.

BUN

7-20 range -urea nitrogen is the nitrogen portion of urea, a substance formed in the liver through an enzymatic protein breakdown process -urea is normally freely filtered through the renal glomeruli, with a small amount reabsorbed in the tubules and the remainder excreted in teh urine -elevated levels indicate a slowing of glomeruli filtration rate

Promotes sodium reabsorption of water in the kidney and produces a concentrated urine

ADH

A healthcare provider schedules a paracentesis for a client with ascites. What should the nurse include in the client's teaching plan?1 Maintaining a supine position during the procedure2 Consuming a diet low in fat for three days before the procedure3 Emptying the bladder immediately before the procedure4 Staying on a liquid diet for 24 hours after the procedure

Ans: 3The bladder must be emptied immediately before the procedure to decrease the chance of puncture with the trocar used in a paracentesis. A paracentesis usually is performed with the client in the Fowler position to assist the flow of fluid by gravity. Eating a diet low in fat for three days before the procedure is not necessary for a paracentesis. Staying on a liquid diet is not necessary for a paracentesis.

Tx for UTI

Bactrim, macrodantin, cipro, levaquin. -fluids, avoid urinary irritants -hygeine -prevention

which hormone increases blood flow and vascular permeability

Bradykinnins

CVVH

Continuous venovenous hemofiltration -highly permeable membrane -fluid and solute removal via ultrafiltration -filtrate is dicarded -replacement fluid is infused similar to plasma (but no K, urea, Cr, PO4) -used in ICU, runs 12-24h, through double lumen catheter -less drastic fluids shifts.

hyperuricemia

Excess of uric acid in the blood

hyperoxaluria

Excess oxalate in urine

The nurse is educating a couple concerning the process of fertilization. The nurse explains to the couple that which component stimulates the release of estrogen and progesterone after fertilization?

HCG After fertilization, human chorionic gonadotropin (hCG) stimulates the corpus luteum to produce estrogen and progesterone. Inhibin is a hormone produced by the ovarian follicles;

A student nurse is caring for a client with chronic kidney failure who is to be treated with continuous ambulatory peritoneal dialysis (CAPD). Which statement by the student nurse indicates to the primary nurse that the student nurse understands the purpose of this therapy?

It uses the peritoneum as a semipermeable membrane to clear toxins by osmosis and diffusion. -Diffusion [1] [2] moves particles from an area of greater concentration to an area of lesser concentration; osmosis moves fluid from an area of lesser to an area of greater concentration of particles, thereby removing waste products into the dialysate, which is then drained from the abdomen.

KUB

Kidney, ureter, bladder x-ray -an x-ray of the urinary system and adjacent structures to detect urinary calculi

A nurse is notified that the latest potassium level for a client in acute kidney injury is 6.2 mEq (6.2 mmol/L). Which action should the nurse take first?

Take vital signs and notify the primary healthcare provider

phases of AKI

Oliguric diuretic recovery

Which hormone is released in response to low serum levels of calcium?

Parathyroid hormone -If serum calcium levels decline, the parathyroid gland releases parathyroid hormone to maintain calcium homeostasis

A nurse is teaching a birthing/prenatal class about breast-feeding. Which hormone stimulates the production of milk during lactation?

Prolactin

which hormone is secondary to angiotensin and aldosterone?

Renin

RAAS

Renin is released by kidneys in response to decreased blood volume; causes angiotensinogen to split & produce angiotensin I; lungs convert angiotensin I to angiotensin II; angiotensin II stimulates adrenal gland to release aldosterone & causes an increase in peripheral vasoconstriction

Acute Renal Failure

Reversible clinical syndrome whereby there is sudden and pronounced loss of kidney function -occurs over hours to days -Results in kidneys failure to excrete nitrogenous wastes

BUN/creatinine ratio

The BUN level is divided y the creatinine level to obtain the ratio. -when the BUN and serum creatinine levels increase at the same rate, the ratio of BUN to creatinine remains constant. -elevated serum creatinine and BUN levels suggest renal dysfunction -a decreased BUN/Creatinine ratio occurs with fluid volume deficit, obstructive uropathy, catabolic state, and high-protein diet -an increased ratio occurs with fluid volume excess.

Dialysis Rx

Time: 2-5 hours -bath -blood flow rate: 400-450 cc/min -dialysate flow rate: 500-800 cc/min -anticoagulant -additives (anemia (EPO, blood) (bone metabolism- vit D, calcitriol, etc) (meds- abx)

renin

a hormone released in response to decreased renal perfusion. this hormone is responsible for regulating blood pressure.

A client is admitted to the hospital with severe flank pain, nausea, and hematuria caused by a ureteral calculus. What should be the nurse's initial intervention? -strain all urine output -increase oral fluids -obtain urine specimen for culture -administer the prescribed analgesic

administer the prescribed analgesic. -Pain of renal colic may be excruciating; unless relief is obtained, the client will be unable to cooperate with other therapy.

hallmark sign of nephrotic syndrome?

albuminuria exceeding 3.5g/day

Promotes sodium reabsorption and potassium secretion in distal collecting tubules

aldosterone

which hormone influences kidney function?

aldosterone -Released from the adrenal cortex, aldosterone influences kidney function.

oxalate containing stones

allopurinol adn vitamin B6

ASHD

arteriosclerotic heart disease

A client arrives at a health clinic reporting hematuria, frequency, urgency, and pain on urination. Which diagnosis will the nurse most likely observe written in the client's medical record?

cystitisCystitis is an inflammation of the bladder that causes frequency and urgency of urination, pain on micturition, and hematuria. Chronic glomerulonephritis is a disease of the kidney that is associated with manifestations of systemic circulatory overload. Nephrotic syndrome is a condition of increased glomerular permeability characterized by severe proteinuria. Pyelonephritis is a diffuse, pyogenic infection of the pelvis and parenchyma of the kidney that causes flank pain, chills, fever, and weakness.

what would cause increased levels of creatinine clearance

diabetes mellitus exercise pregnancy high protein diets

what would cause decreased levels of creatine kinase?

early pregnancy and small stature

A nurse is caring for a client who is scheduled for cystoscopy. What should the nurse include in the client's postcystoscopy teaching plan? 1.Remain flat in bed for the first 24 hours 2.Increase fluid intake for three to four days postoperatively 3.Notify the nurse if there is any drainage on the dressing 4.Bear down when attempting to void during the first six hours

increase fluid intake for 3 to 4 days postoperatively -flushes the bladder internally and helps decrease the risk of infection and reduce the burning sensation upon urination. Remaining flat in bed for the first 24 hours is unnecessary after a cystoscopy. A cystoscopy is performed through the urethra; a dressing is not necessary. Bearing down increases pressure in the pelvic and perineal area and should be avoided.

Angiotensin II

increases blood pressure by stimulating kidneys to reabsorb more water and by releasing aldosterone

What are the functions of antidiuretic hormone (ADH)? Select all that apply. 1. Controlling calcium balance 2. Increasing arteriole constriction 3. Increasing tubular permeability to water 4. Stimulating the bone marrow to make red blood cells 5. Promoting the reabsorption of sodium in the distal convoluted tubule (DCT)

increasing arteriole constriction, and increasing tubular permeability to water. -Antidiuretic hormone (ADH), also known as vasopressin, is a hormone released from the posterior pituitary gland. ADH increases arteriole constriction and tubular permeability to water. Calcium balance is controlled by blood levels of calcitonin and the parathyroid hormone (PTH). Erythropoietin stimulates the bone marrow to make red blood cells. Aldosterone promotes the reabsorption of sodium in the distal convoluted tubule (DCT).

A nurse is caring for a client with a diagnosis of renal calculi secondary to hyperparathyroidism. Which type of diet should the nurse explore with the client when providing discharge information? 1 Low purine 2 Low calcium 3 High phosphorus 4 High alkaline ash

low calcium Calcium and phosphorus are components of these stones; foods high in calcium and phosphorus should be avoided. Low purine and high alkaline ash diets are indicated for clients with gout. Foods high in phosphorus must be avoided.

Treatment of calciphylaxis

low phosphorous diet, normalizing calcium and phosphate with non-calcium based phosphate binders and low-calcium dialysate. Sodium thiosulphate 25g VI over 30 minutes three treatments per weeks has been shown to improve lesions and should be continued for 2 months beyond the resolution of lesions.

flaccid neurogenic

lower motor neuron lesion. fills then have overflow incontinence

Which hormone elevations indicate Turner syndrome? Select all that apply.

lutropin, follitropin -Elevation of lutropin and follitropin indicates Turner syndrome. Elevation of prolactin indicates possible galactorrhea, pituitary tumor, disease of hypothalamus or pituitary gland,

Serum creatinine

measures effectiveness of renal function. 0.6 to 1.2 mg/dL

albumin levels in urine

men 2-20 women 2.8-28. higher levels indicate microalbuminuria. can also be determined by a 24 h specimen

Urge incontinence

unable to suppress signal from bladder to brain

The nurse providing postoperative care for a client who had kidney surgery reviews the client's urinalysis results. Which urinary finding should the nurse conclude needs to be reported to the primary healthcare provider?

presence of large proteins -The glomeruli are not permeable to large proteins such as albumin or red blood cells (RBCs), and it is abnormal if albumin or RBCs are identified in the urine;

The nurse is caring for a client in the postanesthesia care unit. The client had a suprapubic prostatectomy for cancer of the prostate and has a continuous bladder irrigation (CBI) in place. Which primary goal is the nurse trying to achieve with the CBI?

prevent the development of clots in the bladder.

Calcinosis cutis

refers to calcium deposition in the skin and is a subtype of calcinosis, a condition describing calcification in vessels and organs -painless flexural infiltrating plaques at periarticular sites. -size and number of plaques correlate with degree of hyperphosphatemia does not cause skin necrosis

Dialysate concentrations

sodium 135-155 potassium 0 -4 calcium 1.25 to 1.75 (2.5 to 3.5 meq/L) magnesium 0-0.75 (0-1.5 meq/L) chloride 87 to 120 bicarbonate 25-40 glucose 0 to 0.20

Dialysate Bath

solution that contains water and electrolytes that passes through the artificial kidney to remove excess fluids and wastes from the blood. concentrations of dialysate components used in hemodialysis

Stages of progression of type 1 diabetic renal disease

stage1- at time of diagnosis of diabetes. Kidney size and GFR are increase. Blood sugar control can reverse the changes. Stage 2- 2-3 years after dx. basement membrane changes result in loss of filtration surface area and scar formation. These changes are called glomerulosclerosis Stage 3, 7-15 years after dx. microalbuminuria is present. GFR may be normal or increased Stage 4, albuminuria is detectable by dipstick. GFR decreased. BP is increaed. Retinopathy is present. Stage 5, GFR decreases at an average rate of 10ml/min/year.

A male client has discharge from his penis. Gonorrhea is suspected. To obtain a specimen for a culture, the nurse should:

swab the drainage directly from the urethra to obtain a specimen