RPA 4: Immunity & Epidemiology (Lect. 11-13)
Which of the following provides artificially acquired passive immunity? 1. Receiving a toxoid shot 2. Receiving an antitoxin shot 3. Getting an infection with a virus 4. Babies getting antibodies from their mothers through the placenta 5. 1 & 2
not 1
Which cells produce cytokines that stimulate naive T-helper cells to become active? 1. B-cells 2. Phagocytic cells 3. T-helper cells 4. CTLs 5. 1 & 2 6. 1, 2 & 3 7. 1, 2, 3 & 4
not 4, 5, 6
Your neighbor's child has been diagnosed with an IgG deficiency. What can they do at normal levels? 1. Fix complement 2. Phagocytosis 3. Neutralize infections and toxins 4. Activate CTLs 5. 1 & 2 6. 1, 2 & 3 7. 1, 2, 3 & 4
not 6
Which antibody is used as an epitope-binding receptor on B-cells during clonal selection upon first exposure to the antigen? A. IgA B. IgD C. IgE D. IgG E. IgM
not B
During a primary immune response you will find IgG in the serum in A. A few hours B. 7-10 days C. 26 days D. 40 days E. Never
not C
Which antibody is the primary antibody used in our serum immune responses? A. IgA B. IgD C. IgE D. IgG E. IgM
not E, i think it's A
You inject a baby with pili protein that has been cloned and mass produced. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. whole cell killed F. attenuated G. recombinant DNA
D. recombinant
Which antibody is the first one made during a primary immune response? A. IgA B. IgD C. IgE D. IgG E. IgM
E. IgM
You want to know if your mom is having a systemic immune response to a gastroenteritis virus 2 days after what you think is her first infection. Which of the following types of ELISAs would your run? One that tests for A. IgA B. IgD C. IgE D. IgG E. IgM
E. IgM
Which of the following vaccine types will initiate an infection in a person getting vaccinated? A. toxoid B. antitoxin C. subunit D. recombinant E. attenuated F. recombinant DNA G. all of these will H. none of these, vaccines do not cause infections
E. attenuated
You inject a baby with a virus that has been passaged through tissue culture for multiple generations until it is no longer pathogenic. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. attenuated F. recombinant DNA
E. attenuated
You inject a baby with a virus that has been passaged through tissue culture for multiple generations until it is no longer pathogenic. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. whole cell killed F. attenuated G. recombinant DNA
F. attenuated
A baby getting antibody from its mom's breast milk induces artificially acquired passive immunity True or False
False
A toxoid shot induces artificially acquired passive immunity True or False
False
A toxoid shot induces naturally acquired passive immunity True or False
False
A viral vaccine induces artificially acquired passive immunity True or False
False
All microbes once infecting a host are equally likely to cause symptoms. True or False
False
An antiserum injection induces naturally acquired passive immunity True or False
False
Antibody binding kills microbes True or False
False
If you are infected with a microbe, you will have symptoms of that infection. True or False
False
Injection with a gamma globulin shot will result in the production of memory B-cells True or False
False
Injection with a gamma globulin shots will result in the production of memory T-cells True or False
False
Injection with an antiserum will result in the production of memory B-cells True or False
False
Injection with an antitoxin will result in the production of memory B-cells True or False
False
Injection with an antitoxin will result in the production of memory T-cells True or False
False
Most infections result in disease True or False
False
Neutralization is the activation of complement by antibody binding True or False
False
Only toxins can be neutralized by antibodies True or False
False
Only toxins can be opsonized by antibodies True or False
False
Opsonization is the activation of complement by antibody binding True or False
False
Opsonization is the inhibition of toxin binding to cellular receptors due to antibody binding True or False
False
How a host sleeps can have an effect on whether the host develops a disease during an infection. True or False
True
In order to work maximally, complement requires antibody to pop holes in microbial cell membranes True or False
True
Injection with a toxoid will result in the production of memory B-cells True or False
True
Injection with a toxoid will result in the production of memory T-cells True or False
True
Injection with a viral vaccine will result in the production of memory B-cells True or False
True
Injection with a viral vaccine will result in the production of memory T-cells True or False
True
Most infections do NOT result in symptoms True or False
True
Neutralization is the inhibition of microbe's ability to bind to cellular receptors due to antibody binding True or False
True
Neutralization is the inhibition of toxin binding to cellular receptors due to antibody binding True or False
True
Opsonization is phagocytic cell destruction of microbes due to antibody or complement binding True or False
True
Some pathogens almost always cause disease while others almost never do True or False
True
The host's psychological state can have an effect on whether the host develops a disease during an infection. True or False
True
The route of inoculation can have an effect on whether the host develops a disease during an infection. True or False
True
Which of the following provides artificially acquired active immunity? 1. Receiving a toxoid shot 2. Receiving an antitoxin shot 3. Getting an infection with a virus 4. Babies getting antibodies from their mothers through the placenta 5. 1 & 2
1. Receiving a toxoid shot
What can people with HIV do at normal levels? 1. Respond to microbes they have had a primary immune response to 2. Activate CTLs 3. Produce antibody 4. 1 & 2 5. 1, 2 & 3 6. 1, 2 3 & 4
1. Respond to microbes they have had a primary immune response to
Which of the following provides naturally acquired active immunity? 1. Receiving a toxoid shot 2. Receiving an antitoxin shot 3. Getting an infection with a virus 4. Babies getting antibodies from their mothers through the placenta 5. 1 & 2
3. Getting an infection with a virus
Your neighbor's child has been diagnosed with a IgE deficiency. What can't they do at normal levels? 1. Respond to bacterial infections 2. Respond to infections in the gut 3. Respond to parasite infections 4. Activate B-cells 5. 1 & 2 6. 1, 2 & 3 7. 1, 2, 3 & 4
3. Respond to parasite infections
Which of the following provides naturally acquired passive immunity? 1. Receiving a toxoid shot 2. Receiving an antitoxin shot 3. Getting an infection with a virus 4. Babies getting antibodies from their mothers through the placenta 5. 1 & 2
4. Babies getting antibodies from their mothers through the placenta
Your neighbors child has been diagnosed with a IgM deficiency. What can't they do at normal levels? 1. Produce antibodies at the very early stages of infection 2. Activate B-cells to become plasma cells 3. Respond to infections in the gut 4. Respond to parasite infections 5. 1 & 2 6. 1, 2 & 3 7. 1, 2, 3 & 4
7. 1, 2, 3 & 4
Without the cells that HIV kills, what other parts of the immune system can't function at normal levels? 1. Antibody production 2. CTL killing 3. Complement 4. Phagocytosis 5. Neutralization 6. 1 & 2 1, 2 & 3 7. 1, 2, 3 & 4 8. 1, 2, 3, 4 & 5
8. 1, 2, 3, 4 & 5
During a secondary immune response you will find IgG in A. A few hours B. 7-10 days C. 26 days D. 40 days E. never
A. A few hours
Which antibody would be found in breast milk? A. IgA B. IgD C. IgE D. IgG E. IgM
A. IgA
You want to know if your mom is having an intestinal immune response to a gastroenteritis virus, which causes vomiting. Which of the following types of ELISAs would your run? One that tests for A. IgA B. IgD C. IgE D. IgG E. IgM
A. IgA
You inject a baby with botulism toxin that has been heat inactivated. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. whole cell killed F. attenuated G. recombinant DNA
A. toxoid
Why is PCR superior to ELISA for diagnosis of infection in babies? A. ELISAs often give false negatives B. PCR is more sensitive and can detect the infection sooner C. ELISAs are not reliable in babies because they have their mom's antibodies D. ELISAs are not reliable in babies because they don't have functional immune systems yet E. PCR is more rapid and it is imperative to get babies treatment as quickly as possible.
C. ELISAs are not reliable in babies because they have their mom's antibodies
You want to know if your mom is having an immune response that will elicit histamine release against a worm infection. Which of the following types of ELISAs would your run? One that tests for A. IgA B. IgD C. IgE D. IgG E. IgM
C. IgE
You inject a baby with a capsule that has been removed from a bacterium. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. attenuated F. recombinant DNA
C. subunit
You inject a baby with pili that have been removed from a bacterium. This is an example of a ___________ vaccine A. toxoid B. antitoxin C. subunit D. recombinant E. whole cell killed F. attenuated G. recombinant DNA
C. subunit
You want to know if a baby still has vaccine neutralizing antibody that it received from its mom in utero. Which of the following types of ELISAs would your run? One that tests for A. IgA B. IgD C. IgE D. IgG E. IgM
D. IgG
You want to know if your mom is having a systemic immune response to a gastroenteritis virus, which causes vomiting. Which of the following types of ELISAs would your run? One that tests for A. IgA B. IgD C. IgE D. IgG E. IgM
D. IgG
A host's genetics can have an effect on whether the host develops a disease during an infection. True or False
True
Both microbes and toxins can be neutralized by antibody True or False
True
Getting a viral infection will induce naturally acquired active immunity True or False
True
How a host eats can have an effect on whether the host develops a disease during an infection. True or False
True
