Secretion of Bile by the liver; BIliary functions

600-1000 mL

About how much bile does the liver secrete on a daily basis

Concentrated boiled salts, cholesterol, lecithin and bilirubin

Absorption of water, NaCl and other electrolytes occur in the gallbladder resulting in

lecthin (phospholipids) and electrolytes

Amongst the most abundant substances secreted in the bile please name a couple other than bile salt, bilirubin and cholesterol

Gallbladder

Bile is made in the liver but where is it normally stored

1) detergent action on fat particles in food 2) help in the absorption of FA, monoglycerides, cholesterol and Micelles

Bile salts have 2 important actions in the intestinal tract

Bile acids and cholesterol

Bile secretion occurs in two stages; the first stage the initial secretion contains large amounts of

Bilirubin (end product of heme digestion) Cholesterol

Bile serves as a means of excretion of several important waste products from the blood

Colic acid or deoxycholic acid

Cholesterol is a precursor to the production of bile salts it is first converted into _________ before turning into bile

Sodium and bicarbonate

During the section stage of bile secretion watery solution of _________ is secreted by secretory epithelial cells

Enterohepatic circulation

How do we retain bile salts so they can be used in the future

LOSS OF LIPID SOLUBE VITAMANS A great deal of ingested fats would be lost

If bile salts where not present in the intestinal tract would would occur

Gallbladder for storage

If the sphincter of oddi is closed, the bile is diverted up through the they cystic duct to_________________

Hepatic duct and eventually the common bile duct

Name the passage way bile must travel to reach the duodenum

Acteylcholine — from the vagi and the enteric nervous system

The gallbladder is primarily stimulated by CCK but to a lesser extent what else

Female, forty, fertile and fat

What are 4 factors that play a role in cholesterol and gallstone formation

fat digestion

What is a main function of bile salts

Fatty food in the duodenum

What is a potent activator of CCK release and subsequent emptying of bile from the gallbladder

fat digestion and absorption

What is one of the important roles that bile plays

emptying of bladder

What is one of the main fucntions of CCK

CCK

What is the most potent stimulus for causing the gallbladder to contract

Intestines

Where is the greatest site for bile salts to be reabsorbed