Summary of Acidosis and Alkalosis

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Compensatory Mechanism for Respiratory Alkalosis

renal compensation; decreased excretion of hydrogen ions and decreased reabsorption of bicarbonate. *if compensation is complete, pH will be within normal limit but PCO₂ will be low*

Compensatory Mechanism for Respiratory Acidosis

renal compensation; increases excretion of hydrogen ions and increased reabsorption of bicarbonate. *if compensation is complete, pH of blood will be within normal limits, however the PCO₂ will be high*

Compensatory Mechanism for Metabolic Acidosis

respiratory compensation; hyperventilation increases the loss of carbon dioxide *if compensation is complete, pH will be within normal limits but the bicarbonate will be low*

Compensatory Mechanism for Respiratory Alkalosis

respiratory compensation; hypoventilation slows the loss of carbon dioxide *if compensation is complete, pH will be within normal limits but bicarbonate will be high*

Metabolic Acidosis

decreased bicarbonate below 22 mEq/L and decreased pH below 7.35 if there is no compensation

Respiratory Alkalosis

decreased partial pressure of carbon dioxide to below 35 mmHg and increased pH to above 7.45 if there is no compensation

Common Causes of Respiratory Alkalosis

hyperventilaton due to: oxygen deficiency pulmonary disease cerebrovascular accident (stroke) severe anxiety

Common Causes of Respiratory Acidosis

hypoventilation due to: emphysema pulmonary edema trauma to the respiratory center airway obstruction dysfunction of the muscles of respiration

Metabolic Alkalosis

increased bicarbonate above 26 mEq/L and increased pH above 7.45 if no compensation

Respiratory Acidosis

increased partial pressure of carbon dioxide to above 45 mmHg and decreased pH to below 7.35 if it isn't compensated

Common Causes for Metabolic Acidosis

loss of bicarbonate ions due to: diarrhea accumulation of acid (ketosis) renal dysfunction

Common Causes of Metabolic Alkalosis

Loss of acid due to: vomiting gastric suctioning use of certain diuretics excessive intake of alkaline drugs


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