Varicella Zoster Virus Infections (Smarty PANCE)

When is the varicella vaccine given?

At 12-15 months and 4-6 years of age. (Same as MMR schedule). People 13 years of age and older who have never had chickenpox or never received chickenpox vaccine should get two doses, at least 28 days apart

What is a disease caused by the reactivation of varicella infection that usually presents with a rash in a very specific dermatomal distribution?

Herpes zoster (shingles) is a disease caused by the reactivation of varicella that usually presents with a rash in a very specific dermatomal distribution.

What cranial nerve branch involvement by varicella zoster virus infection can cause herpes zoster ophthalmicus?

Cranial nerve V1 branch involvement by varicella zoster virus infection can cause herpes zoster ophthalmicus.

What name is given to the characteristic chickenpox vesicle surrounded by an erythematous halo?

Dewdrops on a rose petal

What is the most common complication of shingles (from varicella zoster virus)?

Most common complication of shingles (from varicella zoster virus) is postherpetic neuralgia.

One of the classic features of varicella (chickenpox) is that the rash can appear in _______________ all at the same time.

One of the classic features of chickenpox is that the rash can appear in various stages (red spots, blisters, and scabs) all at the same time.

Pain in affected dermatome how many days = postherpetic neuralgia

Pain in affected dermatome > 90 days (3 months) = postherpetic neuralgia

Recombinant zoster vaccine (RZV, Shingrix) is recommended to prevent shingles in adults at what age?

Recombinant zoster vaccine (RZV, Shingrix) is recommended to prevent shingles in adults 50 years and older. It is administered in two doses 2-6 months apart.

What is the route of transmission of the varicella zoster virus.

Respiratory secretions are the route of transmission of the varicella zoster virus.

What is a childhood hepatic encephalopathy associated with viral infection, especially varicella zoster virus and influenza B, that has been treated with aspirin.

Reye syndrome is a childhood hepatic encephalopathy associated with viral infection, especially varicella zoster virus and influenza B, that has been treated with aspirin.

The rash of varicella (chickenpox) often starts on the ____________ ?

The rash often starts on the face, chest, and back before spreading to the rest of the body, including the arms, legs, and even inside the mouth or other mucous membranes

Is the varicella vaccine live or killed?

The varicella vaccine used for routine immunization against varicella zoster virus is a live attenuated vaccine. Pregnant women should not get chickenpox vaccine. They should wait to get chickenpox vaccine until after they have given birth. Women should not get pregnant for 1 month after getting chickenpox vaccine.

What disease is caused by herpesvirus (HHV3) that presents with multiple crops of lesions in various stages, from vesicles to crusts?

Varicella (chicken pox) is a disease caused by HHV3 that presents with multiple crops of lesions in various stages from vesicles to crusts.

Varicella vaccine can be given to HIV patients who have a CD4+ cell count greater than what?

Varicella vaccine, which protects against varicella-zoster virus, is a live-attenuated vaccine that can be given to patients with HIV who have a CD4+ cell count greater than 200 cells/mm3.

Varicella zoster virus belongs to what family of viruses?

Varicella-zoster virus belongs to the human herpesvirus family of viruses (HHV-3)

Herpes zoster virus infection of facial nerve (CN VIII) otalgia, lesions on the ear, auditory canal and TM, facial palsy auditory symptoms

Zoster Oticus (Ramsay-Hunt Syndrome)

Shingles involving CN V, dendritic lesions on slit lamp exam if keratoconjunctivitis is present

Zoster ophthalmicus