20
If a tumor suppressor gene becomes mutated, which of the following is not true?
A "gain-of function" mutation has occurred.
What was the name of the first gene associated with breast cancer?
BRCA1
What do BRCA1 and p53 have in common?
Both are tumor suppressors.
Which of the following is not a characteristic of cancer cells that distinguishes it from normal cells? Cancer cells lack differentiation.
Cancer cells utilize mitosis to divide.
A carcinogen is not a mutagen.
False
If someone has no genetic predisposition to cancer then environmental exposure to carcinogens will not cause them to develop cancer.
False
If you only inherit one mutated copy of BRCA1 and the other copy is normal, you will not develop breast cancer.
False
Both heredity and environmental risk factors come into play in the development of cancer.
True
Which of the following factors can lead to cancer?
all of these can lead to cancer
Which of the following is not found in tobacco smoke?
asbestos
Which is responsible for more cancer deaths in women: breast, colon and rectum, pancreas, or ovary?
breast
Cancers of epithelial tissues are called
carcinomas
Proto-oncogenes
code for proteins that promote the cell cycle.
Which of the following is not a stage in carcinogenesis?
differentiation
A benign tumor is not dangerous because it cannot metastasize.
false
Cancer is a single disease that affects one in three Americans.
false
What type of cancer causes the most deaths in males?
lung and bronchus
Hodgkin lymphomas develop from
mutated B cells
What is the most common cancer found in males?
prostate
Which accounts for more cancer deaths in males: bladder, pancreas, esophagus, or prostate?
prostate
The ends of the chromosomes are "capped" with special repetitive DNA sequences called
telomeres
Which of the following is not a type of proto-oncogene?
the gene for p53
Which of the following is not a type of ionizing radiation?
ultraviolet radiation
Contact inhibition means that
when cells come in contact with a neighbor, they stop dividing.
How many Americans will deal with cancer in their lifetime?
1 in 3
