ABO and H blood group system study questions

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What ABO antibody is expected in this patient serum based on the following information? --- 0 anti-A and 0 anti-B

anti-A and anti-B (group O phenotype with A1 and B antibodies)

Which ABO discrepancy is the best explanation for the results shown in the following chart? --- 4+ anti-A, 0 anti-B; 2+ A1, 4+ B

subgroup of A

Which result is discrepant if the red cell typing shown in the following chart is correct? --- 0 anti-A, 4+ anti-B; 0 A1, 0 B

negative reaction group A1 cells

Which of the following situations may produce ABO discrepancies in the serum testing?

newborn patient with hypogammaglobulinemia cold alloantibody

What soluble antigen forms are detectable in saliva based on the following genotype: AB, HH, SeSe?

only H

What ABO phenotypes would be compatible if the patient required a transfusion of RBCs?

only group O

An individual has the genotype of AO, hh. What antigens would be NOT present on the red cells of this individual?

A only A and H A and O

Which of the following statements is true about ABO antibody production?

ABO antibodies are stimulated by bacteria and other environmental factors

What immunodominant sugar confers B blood group specificity?

D-galactose

Which lectin agglutinates A1 red cells?

Dolichos biflorus

What immunoglobulin class is primarily associated with ABO antibodies?

IgM

What immunodominant sugar determines the specificity of H antigens?

L-fuctose

Select the ABO phenotypes, in order from most frequent to least frequent, that occur in whites.

O, A, B, AB

What gene controls the presence of soluble H substance in saliva?

Se

According to Landsteiner's rule, if a patient has no ABO antibodies after serum testing, what ABO antigens are present on the patient's red cells?

both A and B

Given the following ABo typing results, what is a potential conclusion for these results? --- 4+ anti-A, 4+ anti-B; 1+ A1, 0 B

discrepant results: patient has A antigen on red cells with anti-A in serum (the patient should not have agglutination for anti-A)

What term describes using known sources of reagent antisera (known antibodies) to detect ABO antigens on patient's red cells?

forward grouping

What ABO phenotypes would be compatible if the patient required a transfusion of fresh frozen plasma?

group AB, O, A, or B

What is the ABO interpretation? --- 0 anti-A, 0 anti-B; 4+ A1, 4+ B

group O

What are the gene products of the A and B genes?

transferase enzymes


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