ASCP MT Chem

The expected glucose value of an ABNORMAL 2-hour post-glucose tolerance test is: markedly elevated glucose levels; above fasting levels markedly decreased fasting glucose levels within fasting glucose normal limits slightly below normal glucose levels

markedly elevated glucose levels; above fasting levels An abnormal glucose tolerance test would show that an individual is unable to process glucose properly, leaving very elevated levels in the blood. As with fasting or random blood glucose tests, a markedly abnormal oral glucose tolerance test is diagnostic of diabetes.

The accuracy of an immunoassay is its ability to discriminate between results that are true positives and results that are true negatives. Two parameters of test accuracy are specificity and sensitivity. Which of these statements apply to an immunoassay with high specificity, but low sensitivity? Accurately identifies the presence of disease Accurately identifies the absence of disease Has few false-positives Has few false-negatives

Accurately identifies the absence of disease Has few false-positives A test with high specificity accurately detects the absence of disease. The more specific a test is, the fewer false-positive results will occur. A test with high sensitivity accurately identifies the presence of disease. The more sensitive a test, the fewer false-negative results it produces. In the case stated in this question, the immunoassay has high specificity, so it has few false-positives and will accurately detect those individuals who do not have the disease or condition that is being tested for. However, the test has low sensitivity, so it may not identify all individuals who actually have the disease; it may produce many false-negative results.

A CYP2D6 ultrarapid metabolizer (UM) would require ___________ dose of a drug that is metabolized by CYP2D6 than a CYP2D6 extensive metabolizer (EM). a higher a lower the same

An ultrarapid metabolizer (UM) would require a higher dose of a drug than an EM (a person with normal enzyme activity) since the UM eliminates the drug more quickly.

Which of the following hormones inhibits gluconeogenesis, the formation of glucose from noncarbohydrate sources such as amino acids, glycerol, and fatty acids? Insulin Epinephrine Cortisol Glucagon

Gluconeogenesis is the formation of glucose from noncarbohydrates when carbohydrate intake is absent, a fasting state. The hormone cortisol along with glucagon and epinephrine all stimulate this metabolic pathway. Insulin; however, inhibits this pathway and is therefore the correct answer.