Bio unit 4 test

When the concentration of GAl is highest, the average height of the control seedlings is approximately

10cm

The diagram above illustrates feedback control as exerted by the hormone thyroxine. Following surgical removal of the thyroid gland, the level of TSH in the blood will increase. Which of the following best explains this increase?

A decrease in thyroxine levels means a loss of inhibition to the hypothalamus and anterior pituitary, leading to increased TSH secretion.

The mechanism of action of many common medications involves interfering with the normal pathways that cells use to respond to hormone signals. Which of the following best describes a drug interaction that directly interferes with a signal transduction pathway?

A medication enters the target cell and inhibits an enzyme that normally synthesizes a second messenger.

The diagram above represents a model of signal transduction pathways (I and II) in a cell that is targeted by two different hormones (H1 and H2). The components of the signal transduction pathways are identified in the figure legend. Each cellular molecule in both pathways can exist in an inactive or active form. When the components in pathway I are sequentially activated, the TAP molecules promote cell division. When the components in pathway II are sequentially activated, downstream signaling by the G protein is inhibited. Based on the model, which of the following mutations is most likely to result in a cell that will generate a cancerous tumor?

A mutation in the gene encoding G-PIP that results in a nonfunctional protein

In mammals, an increase in the concentration of sodium in the blood triggers the release of antidiuretic hormone (ADH) from the pituitary gland. As the concentration of sodium in the blood returns to previous levels, the release of ADH from the pituitary gland is reduced. Based on the information presented, which of the following describes the most likely role of ADH in maintaining blood osmolarity?

ADH promotes an increase in the movement of water into the bloodstream.

Damaged tissue releases chemicals that activate platelets and stimulate the formation of blood clots. Which of the following predictions about the activity of platelets best describes a positive feedback mechanism?

Activated platelets release chemicals that activate more platelets.

The endocrine system incorporates feedback mechanisms that maintain homeostasis. Which of the following demonstrates negative feedback by the endocrine system?

After a meal, blood glucose levels become elevated, stimulating beta cells of the pancreas to release insulin into the blood. Excess glucose is then converted to glycogen in the liver, reducing blood glucose levels.

Epinephrine is a protein hormone found in many animals. Epinephrine stimulates a signaling pathway that results in the breakdown of glycogen to glucose in the liver cells. Which of the following describes the initial steps in the process whereby epinephrine stimulates glycogen breakdown?

Epinephrine binds to a cell-surface receptor; the activated receptor stimulates production of the second messenger, cAMP

Melanocytes are skin cells that can become cancerous and develop into a cancer known as melanoma. Some cancerous melanocytes have developed resistance to the drugs currently used to treat melanoma. As a result, researchers are investigating the effects of a new compound (drug XX) on four different melanoma cell lines. Researchers analyzed cell survival in two cell lines (Figure 1) and oxygen consumption in the presence of drug XX in all four cell lines (Figure 2). Figure 3 shows the proposed mechanism by which drug XX affects cells. Figure 1. Percent survival of normal melanocytes and cancerous melanocyte (melanoma) lines 11 and 22 after treatment with different concentrations of drug XX Figure 2. Oxygen consumption per cell in four melanoma lines after treatment with either solvent alone or solvent containing drug XX. Error bars represent ±2SEx¯±2SEx¯. Figure 3. Pathway leading to cell survival, growth, and proliferation and the likely effect of drug XX Which of the following best describes the data in Figure 1 ?

At a concentration above 10 μM drug X reduces melanoma cell survival.

Ethylene gas is an organic molecule that serves many cell signaling roles in flowering plants. Which of the following best explains how a positive feedback mechanism involving ethylene works?

Cells of ripening fruit produce ethylene, which activates the ripening response in other fruit cells.

Which of the following best describes the role of mitosis in the cell cycle?

Distributing replicated chromosomes to daughter nuclei

Figure 1. The relative concentrations of both the cyclin and CDK components of MPF Maturation promoting factor, MPF, is a cyclin-CDK= complex that catalyzes the phosphorylation of other proteins to start mitosis. The activity level of MPF is dependent on the relative concentrations of the cyclin and CDK components of MPF(Figure 1). Based on Figure 1, which of the following describes the role of cyclin in the regulation of the cell cycle?

During M phase, the cyclin level peaks, resulting in an increased binding frequency with CDK.

Two types of cells, alpha and beta cells, produce signaling molecules that affect blood sugar levels in opposite ways (Figure 1). Epinephrine is a chemical, often released during periods of exercise, that ultimately causes an increase in blood sugar levels in the body. Based on Figure 1, which of the following best explains how exercise causes blood glucose levels to rise?

Epinephrine activates alpha cells, causing the release of glucagon, and inhibits beta cells, blocking the release of insulin.

Based on Figure 2, which of the following best supports the claim that drug X inhibits oxygen consumption?

Melanoma line 3 consumes statistically less oxygen per cell in the presence of drug X than it does in the presence of the solvent alone.

A researcher examining a root tip observes a plant cell with condensed sister chromatids, kinetochores with attached microtubules, and individual chromosomes that are aligned at the equatorial plate of the cell. Which of the following best describes what the next process will be in the cell?

Paired chromatids will separate, and the new daughter chromosomes will move toward opposite poles of the cell.

Based on the model of eukaryotic cell cycle regulation shown in the figure, which of the following best describes the effect of a drug that blocks the production of the mitotic cyclin?

The cell would be prevented from entering mitosis, and the cell would stop dividing.

The following questions refer to the data in Figures 1 through 4 below, which were collected during a study of the growth of plant seedlings. Which of the following is a correct conclusion that can be drawn based only on the data in Figure 4?

The greater the inhibition of GAl synthesis, the lower the plant height after 80 days.

Which of the following statements best describes how a growth factor stimulates cell division from outside a cell?

The growth factor binds to receptors on the cell surface, initiating a signal transduction pathway that activates specific target genes.

A researcher has identified a compound that reverses the effect of drug X. Based on Figure 3, which of the following best explains how the compound acts in the pathway to reverse the effects of drug X?

c(Compund is blocking complex b)

DNA replication occurs

during the S phase of the cell cycle