BIOS 484 Unit 1

In the mature central nervous system, glial stem cells with the properties of astrocytes can give rise to

astrocytes, oligodendrocytes, and sometimes neurons.

Which of Camillo Golgi's scientific contributions enabled Santiago Ramón y Cajal to propose the neuron doctrine?

Developing a silver staining method

Which cell produces myelin in the nerves of the peripheral nervous system?

Schwann cell

Which statement best describes most neurons?

They receive inputs on dendrites and output signals at synapses.

Scientists have a new tool shown below that allows them to image activity in neurons in various animals using GCaMP which is shown below. Which of the following best describes how this tool works.

Ca2+ bound CAM interacts with the RS20 domain, leading to full assembly of GFP and increased green fluorescence

Channelrhodpsin, shown below is another cool optogenetic tool. Which of the following does not apply to channelrhodpsin:

Channelrhodopsin was discovered as a naturally occurring protein in mice

Which statement best describes the function of a neuron with multiple, highly branched dendrites and one axon?

It can integrate convergent information from many neurons.

Hydra have several advantages for studying neuronal circuits over mice and flies. Which of the following is not one of them.

The CNS of this bilaterian found close the head, is less complex making it easier to study

Advantages to using hydra to study neuronal circuits

Their small size allows whole animals imaging. Stable genetic lines allow scientists to introduce optogenetic tools to study the neuronal network activity during behaviors. Hydra do not age so imaging experiments can be repeated multiple times in the same specimen. Hydra are transparent allowing easy imaging.