bloodbank chap 4

What is the approximate probability of finding a compatible unit of blood for a D-positive patient with antibodies to C, E, and K, if the frequency of C is 70%, E is 30%, and K is 10%?

2 out of 10 units

In a random population, 16% of the population is homozygous for a particular trait. What percentage of the same population is heterozygous for that particular trait?

48%

What is an advantage of Nucleic Acid Testing (NAT) for viral marker testing?

A small amount of DNA or RNA can be detected

What is the meaning of the term autosomal?

A trait that is not carried on the sex chromosomes

In a family study, all four siblings in the family had a different blood type: A, B, O, and AB. What is the most likely genotypes of the parents?

AO and BO

How are most blood group systems inherited?

Autosomal codominant

Which of the following clinical applications applies to molecular testing for blood group antigens? all

Confirm the D type of blood donors Identify fetus at risk for HDFN Predict the phenotype of a patient with autoimmune hemolytic anemia All of the above

Of the following markers used to test for paternity, which marker provides the most useful statistical value?

Human leukocyte antigen typing

When does crossing over occur?

Meiosis

The children of a group AB mother and a group B father could phenotype as all of the following except:

O.

When an individual is group A, which of the following genetic terms applies?

Phenotype

In the PCR reaction, what is the term for the short pieces of single-stranded DNA that are complementary and mark the sequence to be amplified?

Primers

How is RNA different from DNA? all

RNA usually exists as a single strand. The sugar ribose is substituted for deoxyribose. The base uracil exists only in RNA. All of the above are true.

If two traits occur higher in a population together than each occurs separately, they may be linked. What does this fact suggest?

The genes are close together on the same chromosome.

When using the Hardy-Weinberg equation to calculate genetic frequencies, which of the following must be TRUE? all

The population statistics must be large. Mutations cannot occur. Mating must be random. All of the above are true.

If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N-?

Weaker

A father carries the Xga blood group trait and passes it on to all of his daughters but to none of his sons. What type of inheritance pattern does this demonstrate?

X-linked dominant

A person whose red cells type as M+N+ with antisera would be:

a heterozygote.

The linked HLA genes on each chromosome are inherited as a:

haplotype.

In relationship testing, a "direct exclusion" is established when a genetic marker is:

present in the child but absent in both the mother and alleged father.

Mitosis results in ______________________ chromosomes as the original.

two cells with the same number of