BSC 215 HW bone tissue

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The major organic component of bone extracellular matrix is __________.

collagen

Small cavities that are located between lamellae and contain osteocytes are called __________.

lacunae

Which shape of bone contains a medullary cavity and epiphyseal lines?

long

Bone cells that are found in the endosteum and periosteum and build new bone matrix are called __________.

osteoblasts

Which type of cell is responsible for bone deposition?

osteoblasts

The large, multinucleated cells responsible for bone resorption are called __________.

osteoclasts

The type of bone that has irregularly arranged collagen bundles, abundant osteocytes, and little inorganic matrix, is classified as __________.

primary bone

If a bone is lacking collagen in its organic matrix, such as with the disease osteogenesis imperfecta, the bone would

be brittle and shatters easily.

If primary bone were not replaced by secondary bone,

bone would be less resistant to tensile and compressive forces.

Osteogenesis imperfecta is a congenital bone disease caused by a collagen deficiency. Which of the following would be a symptom of osteogenesis imperfecta?

brittle bones

Which of the following events does NOT happen during endochondral ossification?

Mesenchymal cells differentiate into osteoblasts.

Which of the following events happens during intramembranous ossification?

Mesenchymal cells differentiate into osteoblasts.

Which of the following gives bone its strength and ability to withstand compression and protect?

hydroxyapatite crystals

In certain diseases, osteoclast activity takes over osteoblast activity, which will cause the bone to

increase the breakdown of the ECM without it being rebuilt, leading to a weakening of the bone.

Compact bone forms concentric rings that make it extremely hard and strong to

resist stress and protect the inner spongy bone.

The type of bone that has fully formed lamellae with regularly arranged collagen bundles and a higher percentage of inorganic matrix is classified as __________.

secondary bone

The bony plates visible in this figure are called __________.

trabeculae

If osteoclasts failed to function properly during ossification,

weaker, less organized primary bone would remain.


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