Chapter 30 - Pituitary Drugs
3 forms of octreotide
IV, IM, subQ
which posterior pituitary drug treats hemophilia A?
desmopressin
drug form of cortisol
hydrocortisone
used to prevent or control polydipsia (excessive thirst), polyuria, and dehydration associated with diabetes insipidus. also useful in treating various types of bleeding, particularly GI hemorrhage. (2 drugs)
vasopressin, desmopressin
posterior pituitary medication mimics what hormone?
ADH
The nurse would question a prescription for somatropin in a patient with which condition? Dwarfism Acromegaly Growth failure Hypopituitarism
Acromegaly
octreotide pregnancy cat
B
The nurse is caring for a patient with diabetes insipidus (DI) who is receiving vasopressin. What therapeutic effect does the nurse anticipate with the use of this medication? Increase in thirst Improved skin turgor Decrease in urine output Normal serum albumin level
Decrease in urine output
A patient has developed diabetes insipidus after a head injury. Which medication would the nurse anticipate to be prescribed for the management of DI in this patient? Corticotrophin Octreotide Somatropin Desmopressin
Desmopressin
Which is a priority nursing diagnosis for a patient receiving desmopressin (DDAVP)? Risk for injury Acute pain Excess fluid volume Deficient knowledge regarding medication
Excess fluid volume
After administering somatropin to a patient, the nurse would assess for potential adverse effects of this medication by monitoring which laboratory test result? Glucose Platelets Potassium Magnesium
Glucose
When teaching a patient the adverse effects of desmopressin the nurse will instruct the patient to monitor for which potential side effects? (Select all that apply.) Headache Weight gain Hypotension Nasal irritation Hyperglycemia
Headache Weight gain Nasal irritation
_________ of vasopressin may lead to severe vasoconstriction and tissue necrosis
IV infiltration
The nurse admitting a patient with acromegaly anticipates administering which medication? Corticotropin Desmopressin Octreotide Somatropin
Octreotide (Octreotide suppresses growth hormone. Growth hormone is the cause of acromegaly and therefore is suppressed with medication.)
2 indications of octreotide
alleviating symptoms of carcinoid tumors, treating esophageal varices
use pituitary drugs with extreme caution in pts with acute or chronic illnesses such as (3)
asthma, migraines, epilepsy
pregnancy cat of vaspopressin
c
major drug interaction with octreotide? why?
ciprofloxacin because it prolongs qt interval
a pt is suspected of having adrenocortical insufficiency. Which drug will aid in the diagnosis of this condition?
cosyntropin
used in the diagnosis of adrenocortical insufficiency
cosyntropin
intended therapeutic effect of desmopressin in a pt w diabetes insipidus
decreased thirst
2 drugs with similar actions to naturally occurring anitdiuretic hormone
desmopressin, vasopressin
somatropin and somatrem mimic which hormone? octreotide inhibits it
growth hormone
2 common adverse effects of somatropin
headache, hyperglycemia, flulike symptoms
5 adverse effects of somatropin
headache, injection site reactions, muscle pain, hypoglycemia, hyperglycemia
what can octreotide cause in pts with type 2 diabetes or without diabetes?
hyperglycemia
4 contraindications of somatropin
hypersensitivity, children with closed growth plates, patients with tumors or acute illnesses
What can octreotide cause in pts with type 1 diabetes?
hypoglycemia (severe)
3 forms of vasopressin
nasal spray, IM, IV
1 drug that inhibits growth hormone
octreotide
a patient is experiencing severe diarrhea, flushing, and life threatening hypotension associated with carcinoid crisis. Which pituitary drug will the nurse administer?
octreotide
alleviates symptoms of carcinoid tumors such as flushing, diarrhea, and life threatening hypotension
octreotide
octreotide may enhance the toxic effects of drugs that do what?
prolong QT interval
octreotide should be used in caution in patients with what type of impairment?
renal
4 types of pts vasopressin should be used in caution with
seizures, asthma, cardiovascular disease, renal disease
do not ________ somatropin when administering
shake
a GH indicated for treatment of growth failure due to inadequate endoenous GH secretion or for pts with wasting due to HIV infection
somatropin
2 drugs that mimic growth hormone
somatropin, somatrem
somatropin is generally given ______, but some manufactured products can be given IM
subcutaneously
