cholinergic neurotransmitters and receptors

True or false: the effects of ACh are brief

True: ACh is quickly broken down by acetylcholinesterase

Process of ACh release

1. ACh is stored in synaptic vesicles 2. released into the synaptic cleft 3. binds to cholinergic receptors in the post synaptic membrane

Process of NE release

1. NE stored in synaptic vesicles 2. diffuses across the synaptic cleft 3. binds to adrenergic receptors on the postsynaptic cell membrane

True or False: adrenergic receptors can only bind to epinephrine

False: adrenergic receptors can bind to epinephrine and NE

True or False: Epinephrine is released as a neurotransmitter

False: hormone

Nicotinic receptor

cholinergic receptor, present in the plasma membrane of dendrites and cell bodies of both sympathetic and parasympathetic postganglionic neurons, chromaffin cells and the neuromuscular junction. nicotine binds here.

NE is released by the adrenal medullae. Is it a hormone or neurotransmitter?

hormone

What happens when ACh binds to nicotinic receptors?

it causes a depolarization and excitation of the postsynaptic cell.

What happens when ACh binds to muscarinic receptors?

it causes either depolarization or hyperpolarization depending on the postsynaptic cell.

NE is released by a sympathetic postganglionic neuron. Is it a hormone or neurotransmitter?

neurotransmitter

What do adrenergic neurons release?

norepinephrine (NE) or noradrenalin

muscarinic receptor

present in the plasma membranes of all effectors innervated by parasympathetic axons as well as most sweat glands. muscarine, fungal toxin produced by select mushrooms.

cholinergic neurons

release neurotransmitter acetylcholine: preganglionic neurons, sympathetic postganglionic neurons innervating sweat glands and all parasympathetic postganglion neurons.

true or false: most sypathetic postganglionic neurons are adrenergic

true