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A cell that can differentiate into almost every cell type of the body.

Pluripotent cell

A cell, such as a fertilized egg, that can give rise to all of the cell types in the adult organism.

Totipotent cell

In the microarray procedure, what molecule is labeled with a fluorescent tag?

cDNA

To use a microarray, mRNA from cells of interest are first converted to ________.

cDNA

The proteins ________ work together to cause the release of the transcription factor that is bound by the retinoblastoma protein.

cyclin and cyclin dependent kinase

The protein ________ checks for damaged DNA, thereby acting as a "quality control" for the cell.

p53

DNA microarrays contain ________.

single-stranded DNA

What are the common types of mutations that occur to convert proto-oncogenes to oncogenes?

- Missense Mutations - Gene Amplification - Chromosomal Translocation

A cell that can differentiate into several cell types but far fewer than an embryonic stem cell.

Multipotent cell

Zebrafish naturally have black and white stripes. Why are transgenic zebrafish fluorescent?

The zebrafish shown here are transgenic organisms resulting from a gene addition. These zebrafish received a gene from jellyfish or sea corals that encode a fluorescent protein, causing them to glow green, red, or yellow.

Mutated forms of the Rb protein....

do not bind to E2F thereby promoting uncontrolled cell division.

Which of the following are used to introduce cloned genes into cells for human gene therapy? a) liposomes b) retroviral vectors c) T-DNA vectors d) liposomes and retroviral vectors e) retroviral vectors and T-DNA vectors

liposomes and retroviral vectors

A _________ is a normal cellular gene that through a ____________ mutation becomes an oncogene.

proto-oncogene, gain-of-function

True/ False: DNA microarrays are used to study patterns of gene expression.

True

True/ False: DNA microarrays may be used to study how a cell responds to specific environmental conditions.

True

True/ False: The chromatin immunoprecipitation method can determine whether proteins bind to a particular region of DNA.

True


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