Drugs Used to Treat Neurodegenerative Disorders (Parkinsons )

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The nurse is teaching a patient with Parkinson's disease about levodopa. Which statement by the nurse is accurate regarding drug administration?

"Take this medication with food or antacids to reduce GI upset."

What is the pharmacologic action of entacapone, a potent catechol O methyl transferase (COMT) inhibitor?

Reduces the destruction of dopamine in peripheral tissues

Dopamine agonists have been linked with which adverse effects in patients with Parkinson's disease?

Sudden sleep events

Which cholinergic symptoms of Parkinson's disease are reduced with anticholinergic drugs?

Tremors and drooling

A patient taking rasagiline is assessed by the nurse to have a lasting significant increase in blood pressure. When reviewing the patient's current list of medications, the nurse decides to hold the next dose of:

ciprofloxacin.

The nurse is providing education to a patient recently placed on selegiline disintegrating tablets. Which statement by the patient indicates a need for further teaching?

"I will place the tablet on my tongue before breakfast."

Which vitamin will reduce the therapeutic effects of levodopa?

B6

When a patient taking a monoamine oxidase B inhibitor receives his dietary tray, the nurse knows to remove the:

Cheese

The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago. The patient has a history of coronary artery disease and takes an antihypertensive and aspirin. Which information would support the need for a reduction in medication dosage by the healthcare provider?

Dizziness

What is the rationale for administering levodopa instead of dopamine for treatment of Parkinson's disease?

Dopamine does not cross the blood-brain barrier when administered orally.

The nurse is providing information to a patient recently prescribed entacapone. Which statement is correct?

Dosage must be adjusted according to the patient's response

Which adverse effects associated with levodopa therapy would support the nursing diagnosis risk for injury?

Orthostatic hypotension


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