Emami TD 5/5
LUNG 1/3: 2/3: 3/3: Result:
4500cGy (45Gy) 3000cGy (30Gy) 1750cGy (17.5Gy) Pneumonitis, Firbrosis
The most widely used tolerance dose tables are based on the dose that will result in a ___% complication rate in ___ years (_____ __/__)if the whole organ (__/__) is irradiated
5%, 5, (TD 5/5), (3/3)
KIDNEY 1/3: 2/3: 3/3: Result:
5000cGy (50Gy) 3000cGy (30Gy) 2300cGy (23Gy) Nephritis, Nephrosclerosis
LIVER 1/3: 2/3: 3/3: Result:
5000cGy (50Gy) 3500cGy (35Gy) 3000cGy (30Gy) Liver failure, ascites
SMALL INTESTINE 1/3: 2/3: 3/3: Result:
5000cGy (50Gy) N/A 4000cGy (40Gy) Ulceration, obstruction, perforation, fistula
RIB CAGE 1/3: 2/3: 3/3: Result:
5000cGy (50Gy) N/A N/A Pathologic fracture
EAR MID/EXTERNAL 1/3: 2/3: 3/3: Result:
5500cGy (55Gy) 5500cGy (55Gy) 5500cGy (55Gy) Chronic serous otitis, Deafness
COLON 1/3: 2/3: 3/3: Result:
5500cGy (55Gy) N/A 4500cGy (45Gy) Ulceration, obstruction, perforation/ulceration/fistula
SPINAL CORD 1/3: 2/3: 3/3: Result:
5cm^2 5000cGy (50Gy) 10cm^2 5000cGy (50Gy) 20cm^2 4700cGy (47Gy) Myelitis, Necrosis, Transection
HEART 1/3: 2/3: 3/3: Result:
6000cGy (60Gy) 4500cGy (45Gy) 4000cGy (40Gy) Pericarditis, Pancarditis
BRAIN 1/3: 2/3: 3/3: Result:
6000cGy (60Gy) 5000cGy (50Gy) 4500cGy (45Gy) Necrosis, Infarction
BRAIN STEM 1/3: 2/3: 3/3: Result:
6000cGy (60Gy) 5300cGy (53Gy) 5000cGy (50Gy) Necrosis, Infarction
STOMACH 1/3: 2/3: 3/3: Result:
6000cGy (60Gy) 5500cGy (55Gy) 5000cGy (50Gy) Ulceration, perforation
ESOPHAGUS 1/3: 2/3: 3/3: Result:
6000cGy (60Gy) 5800cGy (58Gy) 5500cGy (55Gy) Stricture, perforation, ulceration
BRACHIAL PLEXUS 1/3: 2/3: 3/3: Result:
6200cGy (62Gy) 6100cGy (61Gy) 6000cGy (60) Clinically apparent nerve damage
T-M JOINT MANDIBLE 1/3: 2/3: 3/3: Result:
6500cGy (65Gy) 6000cGy (60Gy) 6000cGy(60Gy) Marked limitation of joint function
LARYNX 1/3: 2/3: 3/3: Result:
7900cGy (79Gy) 7000cGy (70Gy) 7000cGy (70Gy) Cartilage necrosis
PAROTID 1/3: 2/3: 3/3: Result:
N/A 3200cGy (32Gy) 3200cGy (32Gy) Xerostomia
LARYNX 1/3: 2/3: 3/3: Result:
N/A 4500cGy (45Gy) 4500cGy (45Gy) Laryngeal edema
BLADDER 1/3: 2/3: 3/3: Result:
N/A 8000cGy (80Gy) 6500cGy (65Gy) Ulceration, contracture
CARTILAGE (CHILD) 1/3: 2/3: 3/3: Result:
N/A N/A 1000cGy (10Gy) Arrested growth
BONE (CHILD) 1/3: 2/3: 3/3: Result:
N/A N/A 10cm^2 2000cGy (20Gy) Arrested growth
BONE (ADULT) 1/3: 2/3: 3/3: Result:
N/A N/A 10cm^2 6000cGy (60Gy) Fracture, necrosis
OVARIES 1/3: 2/3: 3/3: Result:
N/A N/A 200-300cGy (2-3Gy) Permanent sterilization
MUSCLE (CHILD) 1/3: 2/3: 3/3: Result:
N/A N/A 2000-3000cGy (20-30Gy) No development
FETUS 1/3: 2/3: 3/3: Result:
N/A N/A 200cGy (2Gy) Death
LYMPH NODES 1/3: 2/3: 3/3: Result:
N/A N/A 4500cGy (45Gy) Atrophy
PITUITARY GLAND 1/3: 2/3: 3/3: Result:
N/A N/A 4500cGy (45Gy) Hypopituitarism
THYROID GLAND 1/3: 2/3: 3/3: Result:
N/A N/A 4500cGy (45Gy) Hypothyroidism
TESTES 1/3: 2/3: 3/3: Result:
N/A N/A 500-1500cGy (5-15Gy) Permanent sterilization
SALIVARY GLAND 1/3: 2/3: 3/3: Result:
N/A N/A 5000cGy (50Gy) Xerostomia
FEMORAL HEAD 1/3: 2/3: 3/3: Result:
N/A N/A 5200cGy (52Gy) Necrosis
CARTILAGE (ADULT) 1/3: 2/3: 3/3: Result:
N/A N/A 6000cGy (60Gy) Necrosis
ORAL MUCOSA 1/3: 2/3: 3/3: Result:
N/A N/A 6000cGy (60Gy) Ulceration, Fibrosis
VAGINA 1/3: 2/3: 3/3: Result:
N/A N/A 9000cGy (90Gy) Ulceration, fistula
BREAST 1/3: 2/3: 3/3: Result:
N/A N/A >5000cGy (50Gy) Atrophy, fibrosis, necrosis
ADRENAL GLAND 1/3: 2/3: 3/3: Result:
N/A N/A >6000cGy (60Gy) Hypoadrenalism
EYE LENS 1/3 & 2/3: 3/3: Result:
No partial volume 250-500cGy (2.5-5Gy) Cataracts
EYE RETINA 1/3 & 2/3: 3/3: Result:
No partial volume 4500cGy (45Gy) Blindness
OPTIC CHIASMA 1/3 & 2/3: 3/3: Result:
No partial volume 5000cGy (50Gy) Blindess
OPTIC NERVE 1/3 & 2/3: 3/3: Result:
No partial volume 5000cGy (50Gy) Blindess
CAUDA EQUINA 1/3 & 2/3: 3/3: Result:
No volume effect 6000cGy (60Gy) Clinically apparent nerve damage
RECTUM 1/3 & 2/3: 3/3: Result: P______, N_____, F____, S_____, U______, S______
No volume effect 6000cGy (60Gy) Proctitis, necrosis, fistula, stenosis, ulceration, stricture
TD5/5 ______ as the volume _____ TD5/5 ______ as the volume _____
increases, decreases decreases, increases
Doses higher than those listed in the "3/3" column are likely to cause ______ ______ or even _____
severe damage, death
SKIN 1/3: 2/3: 3/3: Result:
10cm^2 7000cGy (70Gy) 10cm^2 6000cGy (60Gy) 10cm^2 5500cGy (55Gy) Necrosis, Ulceration, Fibrosis
BONE MARROW 1/3: 2/3: 3/3: Result:
2000cGy (20Gy) N/A 200cGy (2Gy) Hypoplasia
EAR MID/EXTERNAL 1/3: 2/3: 3/3: Result:
3000cGy (30Gy) 3000cGy (30Gy) 3000cGy (30Gy) Acute serous otitis
