Exam 1- Immunology

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types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells

B cells

Humoral immunity is mediated by antibodies from____ and is involved in the elimination of____ pathogens. Cell mediated immunity is mediated by____ and is involved in the elimination of____ pathogens

B lymphocytes; Extracellular; T lymphocytes; Intracellular

_____________ is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells

CD4+

What is the transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?

CD8 +

What type of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?

Dendritic

Which of the following is NOT a major feature (characteristic) of the adaptive immune system? A. Specificity B. Diversity C. Memory D. Improvement E. Speed

E. Speed

What stage of an adaptive immune response involves proliferation of cells with matching receptors?

activation phase

T cells are made in the____ and complete their differentiation in the____.

bone marrow; thyroid

What stage of an adaptive immune response involves recognition of antigen?

cognitive phase

What stage of an adaptive immune response involves eventual elimination of antigen

effector phase

What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?'

effector phase

T/F: In a resting lymphocyte, B cells and T cells can be distinguished from each other via a simple blood smear.

false

What is the function of eosinophils?

kill parasites

_________ is the type of antigen presenting cells (APCs) is specialized for degradation and presentation of particulate antigens to T cells?

macrophages

An individual is bitten by a dog with rabies and begins to develop antibodies againstthe rabies. These antibodies are harvested and transferred to unimmunized individuals toconfer protection more rapidly for these individuals. This is an example of:

passive immunity

What is the function of neutrophils?

phagocytosis and bacteriocidal mechanisms

What is the function of tissue mast cells?

phagocytosis and bacteriocidal mechanisms, antigen presentation

__________ produce large amounts of antibodies (Igs) and differentiate upon stimulation from CD4+ cells

plasma cells (B cells)

Antigen presenting cells (APCs) include macrophages and dendritic cells, which arefound in lymphoid tissues and the____. These are critical in the uptake and presentationof antigen to T cells.

skin


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