GIT QB
all of the following statements about bile pigments are true except
estrogen
about the cephalic phase of gastric secretion, all of the followings are true exept
excessive amount of bile salts, aspirin or ethanol
the intestinal brush border help digestion by the following except
facilitating movements of intestinal content
all of the following statements about pancreatic secretion are true except
failure of both pancreatic and biliary secretions is needed before steatorrhea develops
Liver functions include all of the followings except
formation of essential amino acids
The following statements about gastric secretion are correct except
gastric secretion is associated with increased H+ concentration in venous blood coming from stomach
about the GIP, all the following are true except
its release is stimulated by presence of excess fat
all of the followings are correct about gastrin except
its secretion is increased by secretin
all of the following statements concerning pancreatic secretions are true except
its secretion is primarily under rural control
concerning HCL secretion all the following are true except
its stimulated by gastrin, acetylcholine, histamine and NE
Which of the following is the major factor that protects the duodenal mucosa from the damage by gastric acid
pancreatic bicarbonate secretions
The secretion of the intrinsic factor occurs in
parietal cells of the stomach
intestinal proteolysis is caused by the following except
pepsin
all of the following statements are untrue except
peptic ulcers tend to heal by removal of the pyloric antrum
Distension of the stomach
results in an increase in the volume of the stomach with a little rise in the intragastric pressure
Which of the following substances is released from the duodenal mucosa in response to acidic gastric juice
secretin
trypsinogen in pancreatic juice is activated by
secretin
emptying of all bladder is stimulated by the following except
sympathetic stimulation
which of the following statement is wrong
the cephalic phase of gastric secretion involves no release of gastrin
a likely reason why a to and fro motion, such as the encountered during airplane flights or in an automobile ride over a bumpy road, tends to cause nausea and vomiting, is because during such motions
the cerebellum is strongly inhibited
which of the following statements are wrong
the enterogastric reflex is of value in facilitating carbohydrates digestion
The following statements about pancreatic secretion are false except
the hormone which stimulates enzyme rich secretion also causes contraction of gall bladder
The gastric peristalsis
the intrinsic factors is secreted by the parietal cells of the gastric mucosa
Which of the following statement is true
the stomach lacks villous membranes
the GIT hormone are characterized by all of the following except
their effects are abolished by cutting the nervous connections of GIT
about pepsins
their optimum pH action is 1.6-3.2
The following statement about bile salts are correct except
they are Na and K salts of bile acids conjugated with glucornic acid
the following statements about bile salts are true except
they are actively absorbed from duodenum
all of the following are correct statements about liver cells except
they are the only site of synthesis of plasma globulins
Chemotrypsinogen in pancreatic juice is activated by
trypsin
The secretion of gastrin by th pyloric antrum ceases
when the gastric mucosa contents have a pH of about 2.0
The secretion of gastric cease
when the pH of the gastric content is decreased below 2
Under the normal conditions, the bulk of gastric secretions are produces
while the food stays in the stomach
secretin is released by
S cells in the duodenal mucosa
a major part of the gall bladder contraction are due to
a hormone synthesized by duodenal mucosa
The chyme entering the small intestine causes a release of secretin which results in
a pancreatic secretion whose pH is just right for action of the pancreatic enzymes that are eventually released
The would predispose the patient to which of the following
anaemia
the secretin hormone
increases the pancreatic secretion of water and HCO3
it is known that secretin
is a small polypeptide synthesized by the intestinal mucosa
The cephalic phase of gastric secretion
is controlled by the vagi nerves
Gastric emptying
is inhibited by excessive acidity in the duodenum
Secretin
is released as a result of contact of acid chyme to the duodenal mucosa
The chemoreceptor trigger zone
is responsible for the vomitting produced by emetic drugs
the so-called chemoreceptor trigger zone
is sensitive to the action of morphine
Pepsin, secreted by the gastric mucosa
is synthesized within the chief cells
Which of the following substances is released from the duodenal mucosa in response to acidic gastric juice
it begins only when food is tasted and accounts for most of the gastric secretion
about the gastric motility, all the following is true except
it increases by over dissension of the stomach
about cholecystokinin-pancreozymin all the following are true except
it inhibits both gastric and intestinal motility
Concerning the gastrin, all of the following are true except
it is released only during gastric phase of gastric secretion and increase the secretion of only th oxyntic cells
Concerning the gastrin hormone
it is structurally similar to CCK
the gastric juice has all the following characteristics except
its antibacterial action is produced by its mucous content
the passage of gastric contents to the duodenum may cause
-copious secretion of pancreatic juice rich in bicarbonate -decreased gastric motility -contraction of the gall baldder -release of pancreozymin
....
-depends on the basis of electric rhythm -originiates at the mid point of the greater curvature and increases in intensity as it sweeps towards the pylorus -is associated with a strong contraction of the antrum and the end of each wave
The normally innervated stomach
-is stimulated to secrete gastric juice when foo dis chewed, even if its not swallowed -cant secrete HCL when its H1 histamine receptors are blocked - the denervated stomach can secrete gastric juice after a meal is ingested -empites more quickly than the denervated stomach
a 45- year old man is found to have a condition in which th parietal cells of his stomach have been destroyed by an autoimmune mechanism. This condition is often associated with which of the following
-pernicious anaemia
The main function of the cardiac sphincter of the stomach is to
-present the reflux of the gastric content to the esophagus -secretin
The lower esophageal sphincter
-prevents reflux of the gastric content into the esophagus -relaxes in response to the peristaltic waves passing down the esophagus -it is abnormally contracted in achalasia -is tonically contracted by high doses of gastrin hormone
vagotomy prevents increased gastric secretion in response to
-sight and smell of food -injection of insulin -emotional disturbances
VIP causes
-stimulation of the intestinal cells to secrete water and electrolytes -inhibition of gastric secretion
The rate of gastric emptying is delayed by
-the enterogastric reflex -GIP
The volume of pancreatic secretion per day is about
1.5 L
the following are true statements about absorption from small intestine except
100 mld
pH of pancreatic secretion is activated by
8
The salivary secretion
A and B are correct
The GIT is controlled by
A,B&C
Oxyntic or parietal cells secrete
HCL
About the GIT hormones affecting gastric function
GIP an dVIP inhibit gastric secretion
HCL secretion includes all of the following processes except
H is exchanged for K from the extracellular fluid
The followings are true statements about absorption from small intestine except
Vit. B12 is absorbed by diffusion
About some GIT hormones
a) gastrin is released as a result of stomach distension and vagal stimulation b) secretin stimulates the pancreatic acing cells to secrete enzymes
Pancreatic secretion is inhibited by all of the followings except
acid in the duodenum
loss of pancreatic secretion produces the following except
alkalosis
-esophageal peristalsis
all are correct
stimulation of gastrointestinal secretion include
all are correct
Gastric HCL secretion
all of the above
Mastication is important because
all of the above
The enterogastric reflex can be elected by which of the following
all of the above
The major factor that stimulates the release of secretin into the blood stream is
an acid pH of the chyme entering the duodenum
Absorption of fat soluble vitamins require the following
bile
pancreatic lipase is activated by
bile salts
acid secretion in ulcer disease can be reduced by which of the following
blockage of histamine H2 receptors
man is unable to digest dietary
cellulose
its believed that in the parietal cells of the gastric mucosa, an active transport system is responsible for the transmembrane passage of
chloride
acidification of the duodenum will
decrease gastric emptying
Inhibition of the myenteric plexus leads to which of the following
decreased gut motility
Vitamin B12 absorption
depends on presence of intrinsic factor
the salivary amylase
digest mainly cooked starch
Gastric peristalsis
ejects all the contents of the antrum into the duodenum
a pyloric obstruction in an infant which results in a prolonged bout of sever vomitting is likely to cause a primary
enterokinase
A 42- year old salesman presents with the chief complaint of intermittent midepigastric pain that is relieved by antacids or eating. gastric analysis reveals that basal and maximal acid output exceed normal values. the gastric hyper secretion can be explained by an increase in the plasma concentration of which of the following
gastrin
Lactase enzyme splits lactose into
glucose and galactose
the major site of absorption of Bit B 12 is
ileum
Under normal condition the gastric secretion is
increased by distention of the stomach
the following stimulate pancreatic secretion rich in enzymes and poor in HCO3 except
nucleotidase
Gastric secretion is inhibited by all the following except
presence of excess protein digestive products in the stomach
it is known that gastin
reaches the secretory cells of the fundus of the stomach through the blood and not through the lumen
Cholecystokinin
release is stimulated by protein hydrolysates in the lumen of the small intestine
HCL secretion in the stomach
require presence of carbonic anhydrase enzyme
hydrochloric acid secretion
requires the dissociation of water with subsequent exchange of the hydrogen ion for potassium ion
mucous presents on the surface of the mucosa of the stomach, small and large intestine is
resistant to enzymes secreted into the lumen of the gastrointestinal tract
stimulation of sub mucosal plexus resulting in an increase in which of the following
secretion of the gut
