Immune System PME
delavirdine
HIV-1 infection
paclitaxel
Kaposi's sarcoma
A client is about to start taking mercaptopurine to treat acute lymphocytic leukemia. You should instruct the client to watch for and report which of the following indications of an adverse effect of this drug? a. bruising b. paresthesias c. blurred vision d. tinnitus
a
A nurse is caring for a client who has a new prescription for delavirdine therapy to treat HIV-1. The nurse should instruct the client to report which of the following adverse reactions to this drug? a. rash b. insomnia c. rhinitis d. alopecia
a
A nurse is caring for a client who is prescribed zidovudine. Which of the following laboratory values should the nurse report to the provider? a. hemoglobin 7.1 g/dL b. RBC count 5.2/mm3 c. neutrophil 57% d. triglycerides 125 mg/dL
a
A nurse is teaching a client who has a new diagnosis of breast cancer about the drug tamoxifen. The nurse should tell the client that which of the following conditions is a contraindication for taking tamoxifen? a. DVT b. COPD c. DM d. alcohol use disorder
a
A nurse is teaching the guardian of a 4-month-old infant about recommended immunizations for the infant. Which of the following immunizations should the nurse include? a. Haemophilus influenzae type B vaccine (Hib) b. varicella vaccine c. meningococcal conjugate vaccine (MCV4) d. tetanus-diphtheria-acelluar pertussis vaccine (Tdap)
a
A client is about to start taking ritonavir to treat HIV-1 infection. Which of the following instructions should you include when talking with the client about taking this drug? (select all that apply) a. expect periodic blood glucose testing b. take it on an empty stomach c. watch for and report jaundice d. increase weight bearing activity e. expect periodic cholesterol testing
a, c, d, e
You should monitor this client for which of the following indications of an adverse rxn to cyclophosphamide? a. gynecomastia b. dilated pupils c. bradycardia d. fever
d
natural passive immunity
- antibodies - directly transfers antibodies to fetus through placenta - directly transfers antibodies to newborn through breast milk
artificial passive immunity
- antitoxin or immunoglobulin - directly injected antibodies or immunoglobulins - after exposure to a communicable disease, confers temporary defense against that disease until body's defenses mobilize - confers temporary defense against communicable disease in immunocompromised clients - example: immunoglobulin: hepatitis in clients not previously vaccinated
carmustine
GI adenocarcinoma
A nurse is caring for a client who has a new prescription for cisplatin to treat testicular cancer. The nurse should instruct the client to report which of the following adverse effects? (select all that apply) a. paresthesia b. sore throat c. flank pain d. tinnitus e. conjunctivitis
a, b, c, d
You should give the client which of the following instructions about chemotherapy with doxorubicin? (select all that apply) a. report vaginal itching b. expect red-tinged tears c. use effective contraception d. expect regrowth after hair loss e. increase intake of calcium and vit D
a, b, c, d
enfuvirtide
advanced or resistant HIV disease
A nurse should recognize that enfuvirtide can be prescribed to clients who have which of the following conditions? a. advanced prostate cancer b. primary brain tumors c. advanced HIV d. metastatic ovarian cancer
c
You are assessing a client who is receiving imatinib to treat chronic myeloid leukemia. Which of the following findings might indicate an adverse reaction to this drug? a. bradycardia b. dry mouth c. constricted pupils d. crackles at lung bases
d
tamoxifen
estrogen-receptor-positive breast cancer
flutamide
prostate cancer
A nurse is preparing to administer the measles, mumps, and rubella (MMR) vaccine to a child. The nurse should recognize that the MMR vaccine provides which of the following types of immunity? a. artificial active immunity b. active c. passive d. artificial passive immunity
a
A nurse is teaching a client who has a new prescription for imatinib to treat chronic myeloid leukemia. Which of the following instructions should the nurse include? (select all that apply) a. clean fruits and veggies thoroughly b. increase calcium intake c. weigh yourself daily d. perform hand hygiene frequently e. avoid grapefruit and grapefruit juice
a, c, d, e
While administering trastuzumab IV to a client who has breast cancer, you should ensure that you have which of the following drugs available to treat an adverse reaction to this drug? a. protamine b. epinephrine c. glucagon (GlucaGen) d. atropine
b
cyclophosphamide
multiple myeloma
A nurse is caring for a client who is receiving vincristine to treat lung cancer. The nurse should monitor the client and recognize which of the following manifestations as an indication that the client is experiencing an adverse effect of the drug? a. weak hand grasp b. constricted pupils c. bradycardia d. crackles
a
cytarabine
acute myelocytic leukemia
A nurse is caring for a client who has a new prescription for ritonavir and zidovudine therapy to treat HIV-1. The nurse should inform the client that zidovudine is prescribed with ritonavir for which of the following reasons? a. to prevent an infusion reaction b. to increase platelet production c. to protect healthy cells from the toxic effects of ritonavir d. to prevent drug resistance
d
natural active immunity
- active infection - client's body produces antibodies against active infection - confers limited or lifelong protection against reinfection
You should instruct a client who is taking tamoxifen to treat breast cancer to watch for and report which of the following serious adverse effects of this drug? a. abnormal menstrual bleeding b. muscle pain and weakness c. yellowing of skin and eyes d. peripheral edema
a
During IV administration of doxorubicin, the infusion site becomes swollen, red, and painful. Which of the following actions should you take? a. slow the infusion rate b. apply pressure to the site c. stop the IV infusion d. apply ice and continue the infusion
c
A nurse is considering drug therapy options for a client who has metastatic breast cancer that is positive for human epidermal growth factor receptor 2 (HER2). Which of the following drugs should the nurse expect the provider to prescribe? a. trastuzumab b. imatinib c. leuprolide d. flutamide
a
A nurse is instructing a client how to self-administer enfuvirtide. Which of the following instructions should the nurse include? a. "allow the vial to sit until the solution is completely clear and without particulates" b. "after reconstituting with sterile water, vigorously shake the vial to mix the solution" c. "use the medication immediately upon removing from the refrigerator" d. "use the same location for 5 injections before rotating to a new site"
a
A nurse is teaching a client about immunizations. Which of the following information should the nurse include about the teaching? a. "you should receive a tetanus booster every 10 years" b. "you should not receive the influenza immunization if you have a common cold" c. "you do not have to receive the shingles vaccine if you have received 2 doses of the varicella virus vaccine" d. "as long as you don't have risk factors, you will start receiving the pneumococcal vaccine when you are 50 years old"
a
A nurse is teaching a client about maraviroc. Which of the following instructions should the nurse include? a. "it is important to report any noticeable rash immediately as it might indicate an issue with your liver" b. "make sure you take this medication without any other medications first thing in the morning" c. "you might experience flu-like symptoms for which you can take any OTC medication" d. "the side effects of this medication are minimal, so you can continue to work and drive as normal"
a
A nurse is teaching a client about recommended immunizations. Which of the following immunizations should the nurse recommend the client receive starting at 50 years of age? a. herpes zoster vaccine b. human papillomavirus vaccine (HPV) c. pneumococcal vaccine d. Haemophilus influenzae type B vaccine (Hib)
a
A nurse is teaching a guardian of a child about the recommended age range to receive the human papillomavirus (HPV) vaccine. Which of the following age ranges should the nurse include? a. 11-12 years old b. 7-9 years old c. 13-15 years old d. 15-17 years old
a
You are caring for a client who is pregnant and is HIV-positive. Which of the following drugs helps prevent the transfer of HIV to the fetus? a. anaztrozole b. zidovudine c. tamoxifen d. trastuzumab
b
A client is about to start therapy with topotecan to treat metastatic ovarian cancer. To minimize neutropenia, an adverse effect of topotecan, you should administer filgrastim at which of the following times? a. 24 hours before the topotecan infusion b. at the same time as the topotecan infusion c. 24 hours after the topotecan infusion d. 1 hour before the topotecan infusion
c
A nurse is caring for a client who has a new prescription for topotecan therapy to treat resistant, small-cell lung cancer. The nurse should advise the client against taking which of the following types of over-the-counter drugs while receiving the therapy? a. folic acid b. St. John's wort c. ibuprofen d. aluminum hydroxide
c
You are administering cyclophosphamide and mesna to a client. Mesna, a chemoprotective agent, helps prevent which adverse rxns to cyclophosphamide? a. retinopathy b. seizure activity c. hemorrhagic cystitis d. cardiotoxicity
c
A nurse is caring for a client who has a new prescription for intrathecal cytarabine therapy to treat meningeal leukemia. The nurse should inform the client that they will also receive which of the following drugs to reduce the risk of neurotoxicity? a. diphenhydramine b. leucovorin c. folic acid d. dexamethasone
d
A nurse is assessing a client following trastuzumab infusion to treat metastatic breast cancer. Which of the following should the nurse recognize as an indication that the client is experiencing an adverse reaction to the drug? (select all that apply) a. wheezing b. dysrhythmias c. hypotension d. fever e. ascites
a, b, c, d
You are about to administer cisplatin to a client who has ovarian cancer. Before beginning the infusion, you should take which of the following actions? (select all that apply) a. infuse 1-2 L of IV fluid b. check the client's peripheral pulses c. administer an antiemetic d. evaluate the client's hearing e. determine the client's weight
a, c, d, e
A nurse should recognize that maraviroc is used in the treatment of which of the following conditions? a. DM b. meningeal infection c. pancreatitis d. chemokine receptor 5 (CCR5)-tropic HIV-1
d
A nurse should recognize that raltegravir is used to treat clients who have which of the following conditions? a. hairy cell leukemia b. thyroid cancer c. Kaposi's sarcoma d. resistant HIV
d
A nurse is preparing a client who has a new prescription for maraviroc therapy. The nurse should instruct the client to report which of the following adverse effects? (select all that apply) a. paresthesia b. cough c. tinnitus d. jaundice e. fever
a, b, d, e
When talking with the client about chemotherapy with doxorubicin, you explain the need for periodic diagnostic tests. The result of which of the following diagnostic tests or procedures requires monitoring? a. lumbar puncture b. IV pyelogram c. bone density scan d. ECG
d
artificial active immunity
vaccine or toxoid - stimulates antigen-antibody response - confers temporary or lifelong immunity to certain communicable disease example: - MMR vaccine: lasts lifetime after initial series of immunizations - tetanus toxoid: tetanus; lasts 10 years - hep B vaccine: after a series of immunizations, lasts at least 5-7 years
A nurse is teaching a client who has a new prescription for mercaptopurine to treat leukemia. Which of the following instructions should the nurse include? (select all that apply) a. use contraception if pregnancy is a risk b. perform oral hygiene frequently c. avoid activities that require mental alertness d. perform hand hygiene frequently e. avoid activities that can cause injury
a, b, d, e
A nurse is preparing to administer enfuvirtide to a client. Which of the following actions should the nurse plan to perform? (select all that apply) a. administer the drug subcutaneously b. discard the unused portion c. roll the vial gently to reconstitute the solution d. inject the solution at room temp e. expect a cloudy solution
a, c, d
A nurse is preparing to administer paclitaxel IV to a client who has ovarian cancer. Which of the following actions should the nurse take? (select all that apply) a. give the patient an antihistamine b. infuse the drug over 1 hr c. administer the drug through non-PVC tubing d. use an in-line filter e. add heparin to the paclitaxel solution
a, c, d
