Immunology Exam 3 Quiz Questions

What is the most common way to test a patient for an HIV infection? A: Test for anti-HIV antibodies B: Count CD4+ T-cells C: Look for HIV infected macrophages under microscope D: Check patient for swollen lymph nodes

A: Test for anti-HIV antibodies

A primary immune response against influenza virus produces antibodies that bind to _____. A: hemagglutinin and neuraminidase B: variable surface glycoproteins C: EBNA-1 D: protein toxins E: gp41 and gp120.

A: hemagglutinin and neuraminidase

Epstein±Barr virus-infected cells are poor targets for CD8 T-cell killing because _____. A: the virus inhibits MHC class I expression B: the virus escapes from the phagosome into the cytosol C: infected cells do not express any viral proteins during latency X D: the proteasome cannot generate viral peptides for presentation by MHC class I molecules

A: the virus inhibits MHC class I expression

The mode of evolution responsible for the production of recombinant influenza viruses composed of a genome derived from two different influenza variants is called _____. A: gene conversion B: antigenic shift C: latency D: immune evasion E: antigenic drift.

B: antigenic shift

If given information from several labs, which of the following would be most closely associated with the patient's risk of getting an opportunistic infection? A: HIV viral load in plasma B: Total white blood cell count C: CD4+ T-cell count D: Anti-HIV antibody level in plasma

C: CD4+ T-cell count

Genes encoding _____ rearrange in trypanosomes permitting replication and survival of the pathogen until the host produces an antibody response against the altered gene product. A: pilin B: flagellin C: variable surface glycoproteins (VSGs) D: hemagglutinin

C: variable surface glycoproteins (VSGs)

The serotypes of Streptococcus pneumoniae differ in their _____. A: superantigen products B: ability to fix complement C: rates of gene conversion D: capsular polysaccharides E: variable surface glycoproteins

D: capsular polysaccharides

Which of the following is a strategy used by the syphilis bacterium Treponema pallidum to avoid immune detection? A: commandeering the macrophage phagocytic pathway to allow survival within the phagosome B: escape from the phagosome to permit infection within the cytoplasm C: creation of a microenvironment within infected cells that promotes treponeme survival D: coating with human proteins E: genetic conversion to produce different variable surface proteins during the course of an infection

D: coating with human proteins

An epidemic affects _____, whereas a pandemic affects _____. A: susceptible individuals; immune individuals B: immune individuals; susceptible individuals C: global populations; local populations D: local populations; global populations.

D: local populations; global populations.

_____ is a strategy used by herpesviruses where replication and the generation of virus-derived peptides are avoided in order to hide from the immune response. A: latency B: antigenic shift C: antigenic drift D: seroconversion E: gene conversion.

A. latency